ERYTHROPOIESIS AND FACTORS REGULATING ERYTHROPOIESIS – 100 MCQs
1. What is erythropoiesis?
A. Formation of white blood cells
B. Formation of red blood cells
C. Formation of platelets
D. Formation of plasma
Answer: B. Formation of red blood cells
2. Where does erythropoiesis occur in adults?
A. Liver
B. Spleen
C. Bone marrow
D. Kidney
Answer: C. Bone marrow
3. In the fetus, the main site of erythropoiesis is:
A. Bone marrow
B. Liver
C. Kidney
D. Lungs
Answer: B. Liver
4. What is the first cell stage in erythropoiesis?
A. Reticulocyte
B. Proerythroblast
C. Hemocytoblast
D. Normoblast
Answer: C. Hemocytoblast
5. Which hormone controls erythropoiesis?
A. Insulin
B. Thyroxine
C. Erythropoietin
D. Cortisol
Answer: C. Erythropoietin
6. Erythropoietin is mainly secreted by:
A. Liver
B. Kidney
C. Spleen
D. Bone marrow
Answer: B. Kidney
, 7. Which factor primarily stimulates erythropoietin secretion?
A. High CO₂ level
B. High oxygen level
C. Low oxygen level (Hypoxia)
D. High pH
Answer: C. Low oxygen level (Hypoxia)
8. The lifespan of a human RBC is approximately:
A. 60 days
B. 90 days
C. 120 days
D. 150 days
Answer: C. 120 days
9. Which nutrient is essential for hemoglobin synthesis?
A. Calcium
B. Iron
C. Potassium
D. Sodium
Answer: B. Iron
10. Which vitamin is required for DNA synthesis during erythropoiesis?
A. Vitamin A
B. Vitamin B12
C. Vitamin D
D. Vitamin K
Answer: B. Vitamin B12
11. Folic acid is required for:
A. Protein synthesis
B. RBC maturation
C. Nerve conduction
D. Lipid metabolism
Answer: B. RBC maturation
12. The immature RBC released into blood is called:
A. Normoblast
B. Reticulocyte
C. Myeloblast
D. Megakaryocyte
, Answer: B. Reticulocyte
13. The nucleus of an RBC is lost during:
A. Proerythroblast stage
B. Early normoblast stage
C. Late normoblast stage
D. Reticulocyte stage
Answer: C. Late normoblast stage
14. The pigment responsible for red color of blood is:
A. Melanin
B. Bilirubin
C. Hemoglobin
D. Myoglobin
Answer: C. Hemoglobin
15. Which organ is known as the “graveyard of RBCs”?
A. Liver
B. Kidney
C. Spleen
D. Bone marrow
Answer: C. Spleen
16. The lifespan of RBCs in the bloodstream is:
A. 90 days
B. 100 days
C. 120 days
D. 200 days
Answer: C. 120 days
17. The precursor cell of all blood cells is:
A. Myeloid cell
B. Hemocytoblast
C. Reticulocyte
D. Normoblast
Answer: B. Hemocytoblast
18. What type of feedback controls erythropoietin release?
A. Positive feedback
1. What is erythropoiesis?
A. Formation of white blood cells
B. Formation of red blood cells
C. Formation of platelets
D. Formation of plasma
Answer: B. Formation of red blood cells
2. Where does erythropoiesis occur in adults?
A. Liver
B. Spleen
C. Bone marrow
D. Kidney
Answer: C. Bone marrow
3. In the fetus, the main site of erythropoiesis is:
A. Bone marrow
B. Liver
C. Kidney
D. Lungs
Answer: B. Liver
4. What is the first cell stage in erythropoiesis?
A. Reticulocyte
B. Proerythroblast
C. Hemocytoblast
D. Normoblast
Answer: C. Hemocytoblast
5. Which hormone controls erythropoiesis?
A. Insulin
B. Thyroxine
C. Erythropoietin
D. Cortisol
Answer: C. Erythropoietin
6. Erythropoietin is mainly secreted by:
A. Liver
B. Kidney
C. Spleen
D. Bone marrow
Answer: B. Kidney
, 7. Which factor primarily stimulates erythropoietin secretion?
A. High CO₂ level
B. High oxygen level
C. Low oxygen level (Hypoxia)
D. High pH
Answer: C. Low oxygen level (Hypoxia)
8. The lifespan of a human RBC is approximately:
A. 60 days
B. 90 days
C. 120 days
D. 150 days
Answer: C. 120 days
9. Which nutrient is essential for hemoglobin synthesis?
A. Calcium
B. Iron
C. Potassium
D. Sodium
Answer: B. Iron
10. Which vitamin is required for DNA synthesis during erythropoiesis?
A. Vitamin A
B. Vitamin B12
C. Vitamin D
D. Vitamin K
Answer: B. Vitamin B12
11. Folic acid is required for:
A. Protein synthesis
B. RBC maturation
C. Nerve conduction
D. Lipid metabolism
Answer: B. RBC maturation
12. The immature RBC released into blood is called:
A. Normoblast
B. Reticulocyte
C. Myeloblast
D. Megakaryocyte
, Answer: B. Reticulocyte
13. The nucleus of an RBC is lost during:
A. Proerythroblast stage
B. Early normoblast stage
C. Late normoblast stage
D. Reticulocyte stage
Answer: C. Late normoblast stage
14. The pigment responsible for red color of blood is:
A. Melanin
B. Bilirubin
C. Hemoglobin
D. Myoglobin
Answer: C. Hemoglobin
15. Which organ is known as the “graveyard of RBCs”?
A. Liver
B. Kidney
C. Spleen
D. Bone marrow
Answer: C. Spleen
16. The lifespan of RBCs in the bloodstream is:
A. 90 days
B. 100 days
C. 120 days
D. 200 days
Answer: C. 120 days
17. The precursor cell of all blood cells is:
A. Myeloid cell
B. Hemocytoblast
C. Reticulocyte
D. Normoblast
Answer: B. Hemocytoblast
18. What type of feedback controls erythropoietin release?
A. Positive feedback
