ETX 10 EXAM 2 QUESTIONS AND ANSWERS ALREADY PASSED
What are some extrinsic vulnerabilities of exposure that children experience relative to adults?
You can pick more than one - Answers -children crawl
-children put items in their mouth
what are some intrinsic susceptibilities to toxicity that children experience relative to adults?
You can pick more than one - Answers -children breathe more for their size
-children eat more for their size
-children have more a permeable blood-brain barrier
-children have more permeable skin
What drug was used to prevent morning sickness resulted in children born with missing thumbs?
- Answers Thalidomide
Preventing the ability of cereblon protein to bind thalidomide to prevent limb deformation is an
example of which of Hill's causal considerations? - Answers Experiment/Reversibility
Exposure to harmful substances at what stage of pregnancy is most likely to cause major
morphological abnormalities? - Answers When the embryo is 3 weeks old
Diethylstilbestrol (DES) is a synthetic estrogen that was used to prevent miscarriage and other
pre-term births until 1971 in the United States. Which groups of people experienced increased
risk of harm to their reproductive tissues as a result of DES? - Answers -The women who took
DES when pregnant
-The daughters of the women who took DES when pregnant
-The sons of the women who took DES when pregnant
-The grandsons of the women who took DES when pregnant
Which of the following are examples of how mutations to DNA can occur? You can choose
,more than one. - Answers -Exposure to radiation from the sun
-Exposure to radiation from a tanning bed
-Exposure to benzo[a]pyrene from cigarette smoke
-Exposure to benzo[a]pyrene from soot
-Mutations just happen
What is cancer? Pick the two best options. - Answers -Abnormal cells dividing without control
-Abnormal cells invading other tissues
Which of the following are hallmarks of Cancer? You can choose more than one. - Answers -
Sustaining proliferative signaling
- Resisting cell death
- Evading growth suppressors
- Inducing aberrant angiogenesis
- Activating invasion and metastasis
Why is the phenomenon of blood vessels going into a mass of abnormal cells 'beneficial' from
the perspective of a cancer? You can choose more than one. - Answers -Blood vessels provide
food/nutrients to the tumor cell mass
-Blood vessels provide oxygen to the tumor cell mass
-Blood vessels provide a route for tumor cell metastasis
How does benzo[a]pyrene cause lung cancer? Choose the best option. - Answers
Benzo[a]pyrene metabolite binds and mutates DNA.
, You are an oncologist, a doctor that treats people with cancer. You work in a clinic that treats
people who get sick on the job, presumably related to their occupations. Mr. Xin comes to see
you and after some careful investigations you discover Mr. Xin has lung cancer. You ask him if
about his life history with the hopes of revealing a cause of his lung cancer. Choose the best
question(s) to ask Mr. Xin based on what you know about lung cancer risk factors. - Answers -
Have you ever smoked or otherwise used tobacco?
-Have you worked on remodeling older homes?
-Have you worked in the basements of homes?
-Have you worked in the chimneys of homes?
How does DES cause breast cancer? Choose the best option. - Answers DES activates Estrogen
Receptor and causes cell proliferation
Not all carcinogens are mutagens. - Answers true
The United States Environmental Protection Agency threshold for an acceptable level of cancer
risk over a lifetime is: - Answers 1 in 10,000
Which company is the single biggest contributor to hot spots of toxic air pollution in the USA? -
Answers The Dow Chemical Company
Why is the ProPublica analysis of excess cancer risk at https://projects.propublica.org/toxmap/
(Links to an external site.) likely underestimating cancer risk? - Answers Because some sources
of carcinogens were excluded
Which of the following are properties of ethylene oxide? You can choose more than one. -
Answers -Difficult to detect
-Sterilizes materials that are difficult to sterilize
-Causes cancer in multiple mammalian species
Identify the best explanation for why the stretch of 80 or so miles from New Orleans to the
Baton Rouge area of Louisiana is called Cancer Alley? - Answers Most of the census tracts with
the highest cancer risk in the country are located in Cancer Alley.
Organic chemical production has risen dramatically due to the production of... - Answers
plastics
What are some extrinsic vulnerabilities of exposure that children experience relative to adults?
You can pick more than one - Answers -children crawl
-children put items in their mouth
what are some intrinsic susceptibilities to toxicity that children experience relative to adults?
You can pick more than one - Answers -children breathe more for their size
-children eat more for their size
-children have more a permeable blood-brain barrier
-children have more permeable skin
What drug was used to prevent morning sickness resulted in children born with missing thumbs?
- Answers Thalidomide
Preventing the ability of cereblon protein to bind thalidomide to prevent limb deformation is an
example of which of Hill's causal considerations? - Answers Experiment/Reversibility
Exposure to harmful substances at what stage of pregnancy is most likely to cause major
morphological abnormalities? - Answers When the embryo is 3 weeks old
Diethylstilbestrol (DES) is a synthetic estrogen that was used to prevent miscarriage and other
pre-term births until 1971 in the United States. Which groups of people experienced increased
risk of harm to their reproductive tissues as a result of DES? - Answers -The women who took
DES when pregnant
-The daughters of the women who took DES when pregnant
-The sons of the women who took DES when pregnant
-The grandsons of the women who took DES when pregnant
Which of the following are examples of how mutations to DNA can occur? You can choose
,more than one. - Answers -Exposure to radiation from the sun
-Exposure to radiation from a tanning bed
-Exposure to benzo[a]pyrene from cigarette smoke
-Exposure to benzo[a]pyrene from soot
-Mutations just happen
What is cancer? Pick the two best options. - Answers -Abnormal cells dividing without control
-Abnormal cells invading other tissues
Which of the following are hallmarks of Cancer? You can choose more than one. - Answers -
Sustaining proliferative signaling
- Resisting cell death
- Evading growth suppressors
- Inducing aberrant angiogenesis
- Activating invasion and metastasis
Why is the phenomenon of blood vessels going into a mass of abnormal cells 'beneficial' from
the perspective of a cancer? You can choose more than one. - Answers -Blood vessels provide
food/nutrients to the tumor cell mass
-Blood vessels provide oxygen to the tumor cell mass
-Blood vessels provide a route for tumor cell metastasis
How does benzo[a]pyrene cause lung cancer? Choose the best option. - Answers
Benzo[a]pyrene metabolite binds and mutates DNA.
, You are an oncologist, a doctor that treats people with cancer. You work in a clinic that treats
people who get sick on the job, presumably related to their occupations. Mr. Xin comes to see
you and after some careful investigations you discover Mr. Xin has lung cancer. You ask him if
about his life history with the hopes of revealing a cause of his lung cancer. Choose the best
question(s) to ask Mr. Xin based on what you know about lung cancer risk factors. - Answers -
Have you ever smoked or otherwise used tobacco?
-Have you worked on remodeling older homes?
-Have you worked in the basements of homes?
-Have you worked in the chimneys of homes?
How does DES cause breast cancer? Choose the best option. - Answers DES activates Estrogen
Receptor and causes cell proliferation
Not all carcinogens are mutagens. - Answers true
The United States Environmental Protection Agency threshold for an acceptable level of cancer
risk over a lifetime is: - Answers 1 in 10,000
Which company is the single biggest contributor to hot spots of toxic air pollution in the USA? -
Answers The Dow Chemical Company
Why is the ProPublica analysis of excess cancer risk at https://projects.propublica.org/toxmap/
(Links to an external site.) likely underestimating cancer risk? - Answers Because some sources
of carcinogens were excluded
Which of the following are properties of ethylene oxide? You can choose more than one. -
Answers -Difficult to detect
-Sterilizes materials that are difficult to sterilize
-Causes cancer in multiple mammalian species
Identify the best explanation for why the stretch of 80 or so miles from New Orleans to the
Baton Rouge area of Louisiana is called Cancer Alley? - Answers Most of the census tracts with
the highest cancer risk in the country are located in Cancer Alley.
Organic chemical production has risen dramatically due to the production of... - Answers
plastics
