CEIL INJURY ANO ADAPTATIOy
SYeversible
ypertroghy Cel grougs in size.
typerplasia - cell dividee cooo.
Metaplasia - changel veploce _physical or funcignal daacterictict
Atoghy cells becamesmalley
Defincion PiNR Yet everything dongathd
Mechanisn,Ratuu. Mucleic aid mesenchyme
CLEAR-> fat T¢ 7spindle
Exoumple
Qutcome
Hypertrophy- : incveaso in side af cel nesu ting iníncraasaiM size cf
offested aGan
ell types- musde styiatzd
smooth.
Mechantsrmsof hyperhapha
nucdeay activty CDNAmANA’ protein prodiuctionl
stimulu
needed foY î mescle bulk
> Phystotagie Hypecheophy
functianal demand i mscle masseXeYC0Sse
i) pregna0y uterine myemetrium Hyperhraphy
(4 Hyperplasia)
incyeasud uorklod - canda munde
Pve load Affey load
Left ventricle
end diadolic vel. k Tetal periherat rAistance
Aovic vegugAaion TPA ie. Hy¡ertenaim
(Heat tt siae)
vol- overlood presse overlsod.
, PRESS URE ovERLOA D
VOLUME NERLOAD
concenhie candioc hypertreph
A0 Apical|
eccertyic
Hyperbrophy
Key mechanism grouth factors
Agorísts
teg. 1GFD
Mechanikal stretch hormone, cngijenslry
Meihanical
dntaxina)
Piak Sgnal traiduction pathuay?
Q-Pydtoup ane anerion kaetors CGRTA4 ,NÍHT, ME
(Poth Hyp
t prodution
‘ synheia
enbryonic14etal gehe o7 cortracile
prettro 4actni
(eg. ArNF, candisc -achn)
4mthanica!
much pertoYmance perfornanee
candiac- -isofor m- B-isolorrm efficiert, Febus
etal heaud musdle attfäeny> adult hecut mscle
Long term (amplication wc0- ondiac kailuy Cif untreatad)
Risk o! neonlasto NIL Cno tetu div. no cancer)
SYeversible
ypertroghy Cel grougs in size.
typerplasia - cell dividee cooo.
Metaplasia - changel veploce _physical or funcignal daacterictict
Atoghy cells becamesmalley
Defincion PiNR Yet everything dongathd
Mechanisn,Ratuu. Mucleic aid mesenchyme
CLEAR-> fat T¢ 7spindle
Exoumple
Qutcome
Hypertrophy- : incveaso in side af cel nesu ting iníncraasaiM size cf
offested aGan
ell types- musde styiatzd
smooth.
Mechantsrmsof hyperhapha
nucdeay activty CDNAmANA’ protein prodiuctionl
stimulu
needed foY î mescle bulk
> Phystotagie Hypecheophy
functianal demand i mscle masseXeYC0Sse
i) pregna0y uterine myemetrium Hyperhraphy
(4 Hyperplasia)
incyeasud uorklod - canda munde
Pve load Affey load
Left ventricle
end diadolic vel. k Tetal periherat rAistance
Aovic vegugAaion TPA ie. Hy¡ertenaim
(Heat tt siae)
vol- overlood presse overlsod.
, PRESS URE ovERLOA D
VOLUME NERLOAD
concenhie candioc hypertreph
A0 Apical|
eccertyic
Hyperbrophy
Key mechanism grouth factors
Agorísts
teg. 1GFD
Mechanikal stretch hormone, cngijenslry
Meihanical
dntaxina)
Piak Sgnal traiduction pathuay?
Q-Pydtoup ane anerion kaetors CGRTA4 ,NÍHT, ME
(Poth Hyp
t prodution
‘ synheia
enbryonic14etal gehe o7 cortracile
prettro 4actni
(eg. ArNF, candisc -achn)
4mthanica!
much pertoYmance perfornanee
candiac- -isofor m- B-isolorrm efficiert, Febus
etal heaud musdle attfäeny> adult hecut mscle
Long term (amplication wc0- ondiac kailuy Cif untreatad)
Risk o! neonlasto NIL Cno tetu div. no cancer)
