1. What vitamin will decrease The use of pyridoxine or Vitamin B6 can be administered for
peripheral neuropathy? patients who are on isoniazid therapy for tuberculosis
Some antiviral drugs that are effective in treating herpes
including acyclovir (first discovered and also available in
generic form), valacyclovir (also available in generic
form), famcyclovir, and pencyclovir. 10% of Valacyclovir is
2. What lab values should be metabolized by the liver, while 90% is metabolized by the
assessed when administering kidney. Thus, Blood Urea Nitrogen (BUN) and creatinine
valacyclovir? levels should be assessed prior to administering
Valacyclovir. Food slows down the absorption, but
overall, it does not affect the absorption of valcyclovir.
Valacyclovir should be taken with a full glass of water and
the patient should increase the water intake.
Oseltamivit, marketed under the trade name Tamiflu, is an
antiviral medication used to treat influenza A and influenza B
3. When should oseltamivir and to prevent flu after exposure. The medications taken
phosphate be prescribed? orally. The CDC recommends use of oseltamivir for
people who have complications or are at high risk for
complications who percent within 48 hours of the first
, symptoms infection.
Rifampin is an antibiotic used to treat a number of bacterial
infections. This includes tuberculosis, leprosy, and legionella
among others. It often is used with other antibiotics. It is also
used to prevent haemophilus influenzae type b and
meningococcal disease in those who have been exposed,
such as people who live in close quarters like soldiers and
4. For what is rifampin prescribed? college students. Before treating someone for a long period
of time testing the liver function and blood counts are
recommended. It is available by mouth and IV. It is also part
of the recommended treatment of active tuberculosis during
pregnancy, even though its safety and pregnancy is not
known. Rifampin is of the erythromycin group of
antibiotics and works. by stopping production of
bacterial RNA
, The adverse effects of Isoniazid that is an antibiotic used a
first line agent for the prevention and treatment of
tuberculosis include; Peripheral neuropathy which is involved
in patients taking isoniazid and it occurs in about 2% of
patients taking 5 mg/kg/d, and the prevalence is higher for
patients taking higher doses, up to about 44% for patients
taking 16 mg/kg/d. The symptoms of peripheral neuropathy
include symmetrical numbness and tingling in the
extremities. The patients who are predisposed to this
adverse reaction include people who are malnourished,
slow acetylators, pregnant women, older adults, diabetics,
and patients with chronic liver disease, including alcoholics.
Peripheral neuropathy with the use of isonazid can be
5. What are the adverse effects
prevented with the use of Pyridoxine (Vitamin B6) and is
of isoniazid (INH)?
recommended for patients in the at-risk groups. The
recommended prophylactic doses range from 10 to 50 mg
daily, while the treatment of established neuropathy requires
50 to 200 mg daily.
Other adverse effects include; elevated serum
transaminases (AST/ALT; liver enzymes) observed in 10% to
20% of patients taking isoniazid occurring usually in the first
3 months of therapy that is asymptomatic, and will return to
normal with continued isoniazid therapy. However, in a small
portion of patients (0.4%), this condition may progress to
hepatic failure or necrosis, and progressive liver damage
that increases with age and the risk is increased by
concurrent alcohol use, and increased 4-fold with concurrent
rifampin administration. In addition, some adverse reactions