Based on the data in figure 21.2, is programmed cell death (apoptosis) required for
normal mouse brain development? - answer Yes
How do various cells in an embryo become "committed" to a particular cell fate? -
answer gradually, regulated by cell signaling and cascades of transcription factors
Which is the characteristic of a determined cell? - answerit is locked into one potential
cell fate
Cell determination is more "rigid" in which group of organisms? - answer animals
What does the experiment in figure 21.13 show about cell fate determination
(commitment)? - answerthe expression of a single gene can alter cell fate
How does the "MyoD" protein work? - answerit is a transcription factor that binds the
enhancers of several muscle-specific genes
What is the concept of "de-differentiation"? - answerit is the idea of reversing
differentiation of cells, to change differentiated cells so that they have more cell fate
potential