NR546 FINAL EXAM STUDY GUIDE FOR NURSING QUESTIONS WITH CORRECT VERIFIED ANSWERS | 100% PASS (A+ CERTIFIED)

NR546 FINAL EXAM STUDY GUIDE FOR NURSING QUESTIONS WITH CORRECT VERIFIED ANSWERS | 100% PASS (A+ CERTIFIED) Monoamine Hypothesis of Depression Correct Answer Depression caused by monoamine neurotransmission deficiency. Monoamine Receptor Hypothesis Correct Answer Abnormal receptors for monoamines may cause depression. Bipolar Disorder Treatment Correct Answer Combine antidepressants with mood stabilizers. SNRI Monitoring Correct Answer Check blood pressure before and during treatment. SSRIs and Suicide Risk Correct Answer Increased risk in children and under 25. Escitalopram Correct Answer SSRI with least CYP interactions. Fluoxetine Half-Life Correct Answer Longest half-life, 1-2 weeks. Paroxetine Risks Correct Answer Contraindicated in pregnancy, causes congenital defects. Sertraline Safety Correct Answer Safe for nursing and breastfeeding. Bupropion Correct Answer Lowest risk of sexual side effects among antidepressants. Serotonin Syndrome Correct Answer Caused by combining serotonergic drugs. MAOIs Correct Answer Inhibit enzyme deactivating dopamine, norepinephrine, serotonin. MAOI Black Box Warning Correct Answer Suicidal ideation risk in young adults. L-Methylfolate Correct Answer Necessary for monoamine synthesis; often deficient. Citalopram Dosage in Older Adults Correct Answer Should be given at half dose. Antidepressants and Older Adults Correct Answer May respond less robustly after age 65. FDA Antidepressant Warning Correct Answer Labeling includes risk of mood switch to mania. Lithium Carbonate Dosage Correct Answer Starting dose reduced by 50% in renal impairment. Infant Irritability Monitoring Correct Answer Important when prescribing SNRIs during breastfeeding. Tricyclic Antidepressants (TCAs) Correct Answer Avoid with other CNS depressants. Lurasidone Administration Correct Answer Take with at least 350 calories for absorption. Mood Stabilizers Monitoring Correct Answer Requires baseline and routine laboratory checks. Antidepressants and Suicide Risk Correct Answer Increase risk of death by suicide in youth. Adjunctive Treatment Correct Answer L-Methylfolate may help alongside antidepressants. Antidepressant Treatment Duration Correct Answer Start for 4-8 weeks at lowest dose. Discontinuation Syndrome Correct Answer More likely with paroxetine after stopping. Lithium levels Correct Answer Increased by NSAIDs and ACE inhibitors; decreased by caffeine. Teratogenic medications Correct Answer Drugs harmful to fetus; contraindicated in pregnancy. Lurasidone Correct Answer Used in pregnancy without teratogenic effects.