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COMSAE 2025 Practice Test: 200 Actual Questions & Detailed Answers | COMLEX-USA Prep

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Ace your COMLEX-USA Level 1 with our COMSAE 2025 practice exam. This PDF features 200 actual exam-style questions, complete with correct and detailed explanations to solidify your understanding. Identify your weak areas, build test-taking confidence, and maximize your score with this essential osteopathic medical student resource.

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COMSAE Exam Newest 2025 Actual Exam
200 Questions And Correct Detailed Answers
(verified Answers) ||Already Graded
A+||Brand New Version!!


Mandibular fracture, nerve that carries the pain sensation
is the - . . ANSWER ✔ ✔inferior alveolar N. Lingual N.
branches off earlier and provides sensation to anterior 2/3
of tongue and floor of mouth.


Patient is retching, vomiting small amount of blood,
history of AUD. Nonpentrating mucosal tear of the
posterior wall superior to the gastroesophageal junction
that continues to the esophageal wall compromises - . .
ANSWER ✔ ✔vagal trunk (runs posterior to the
esophagus). Mallory-Weiss syndrome.


PMH of calcium disorder which he ran out of
supplements. BP is 110/70 and taking BP elicits carpal
spasm. PT is short, stocky and shortened medial digits
(Albright Hereditary Osteodystrophy). Phosphate and
cAMP don't respond to IV PTH. The cause is decreased - . .
ANSWER ✔ ✔Galphas mediated signaling.
Pseudohypoparathyroidism type 1a (PHP1A).

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Fever, dry cough, GI upset with COPD. Patchy opacities.
Gram neg bacilli. They acquired the bacteria via - . .
ANSWER ✔ ✔inhalation if environmental aerosols
(usually HVAC person). Legionella pneumophila.


Sudden loss of consciousness that lasted for less than 1
minute. No tongue biting or urinary incontinence. Most
likely cause - . . ANSWER ✔ ✔idioventricular rhythm.
sudden drop in cerebral perfusion due pacemaker failure.


50 yr old man presents for annual visit. FMH lung and
bladder cancer. Drinks alcohol. PMH hemorrhoids.
Screening for him - . . ANSWER ✔ ✔colonoscopy. Should
be done starting at 45yrs old for everyone.


Low grade lumbosacral achiness for as long as he can
remember. Narrow lucency down the middle of the L5
spinous process present. Patent sacroiliac joints.
Congenital abnormality - . . ANSWER ✔ ✔spina bifida
occulta.

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68 yr old woman with T2DM, HTN, hyperlipidemia.
Menopause at 52. DXA scan -2.1. Add calcium, vitamin D
and what med - . . ANSWER ✔ ✔alendronate to prevent
osteoporosis (Inhibits osteoclast activity, reducing bone
resorption - bisphosphonate)


What is the Pearson correlation value for this data set? - . .
ANSWER ✔ ✔correlation close to 0.00.


78 yr old presents to office with 1 week history of lower
abdominal pain and urinary hesitancy with interrupted
flow. Enlarge, firm, tender prostate. PSA is normal. Gram
pos, catalase neg coccus. Etiological agent - . . ANSWER ✔
✔Enterococcus faecalis .


75 yr old pruritic vulvar lesion which she first noticed 1
week. White, flaky, slightly roughened lesion with focal
areas of ecchymoses from scratching. Thinning of the
squamous epithelium. Hypocellular collagenous tissue. Dx
- . . ANSWER ✔ ✔lichen sclerosus et atrophicus.


37 yr old man presents with pruritus and bullae that are
localized to sun exposed areas of the skin. Urine sample is

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reddish brown in appearance and pink under fluorescent
light. Elevated glucose, alanine aminotransferase,
aspartate aminotransferase. What would be elevated - . .
ANSWER ✔ ✔uroporphyrinogen III. Porphyria cutanea
tarda (PCT).


Weakness and numbness in his right upper extremity
following a shoulder injury. Reveals anesthesia along the
lateral aspect of the arm and forearm, including the
thumb. Biceps ad brachioradialis reflex are 0/4 on the
right and 2/4 on the left. Which additional muscle is
diminished - . . ANSWER ✔ ✔abduction of the humerus.
Axillary n. C5-C6 (from the brachial plexus).


62 yr old is slurring words, talking a lot but not making
sense. Arthroscopic knee surgery 2 weeks ago w/ upper
respiratory tract recently. PMH is on psych drug. Mental
status deteriorates and develops seizure. Low NA, Psych
drug acts by - . . ANSWER ✔ ✔inhibiting serotonin
reuptake. Patient presents with serotonin syndrome due to
SSRI.


7yr old has lethargy, daytime somnolence, nighttime
snoring, increased respiratory infections. DX - . . ANSWER

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