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ATI Pharmacology Content Mastery Series Exam
2025/2026 Questions With 100% Detailed Answers
A nurse is caring for a client who has hyponatremia and is
receiving an infusion of a prescribed hypertonic solution.
Which of the following findings should indicate to the nurse
that the treatment is effective?
a. Absent Chvostek's sign
b. Improved cognition
c. Decreased vomiting
d. Cardiac arrhythmias absent - ANSWER-b. Improved
cognition
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A nurse is teaching a client who has a new prescription for
a nitroglycerin transdermal patch. Which of the following
instructions should the nurse include?
a. "Discontinue the patch if you experience a headache."
b. "Apply a new patch if you have chest pain."
c. "Cover the patch with dry gauze when taking a shower."
d. "Remove the patch prior to going to bed." - ANSWER-d.
"Remove the patch prior to going to bed."
A nurse is reviewing he laboratory results of a client who
has a prescription for sodium polystyrene sulfonate
(Kayexalate) every 6 hr. which of the following should the
nurse report to the provider?
a. Creatinine 0.72 mg/dL
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b. Sodium 138 mEq/L
c. Magnesium 2 mEq/L
d. Potassium 5.2 mEq/L - ANSWER-d. Potassium 5.2
mEq/L - Hyperkalemia (serum potassium level greater
than 5.0 mEq/L) increases the client risk for fatal cardiac
dysrhythmias. Kayexalate is used to decrease the serum
potassium level so the PN should monitor the client's
serum potassium level
A nurse is caring for a client who has tuberculosis and is
taking isoniazid and rifampin. Which of the following
outcomes indicates that the client is adhering to the
medication regimen?
a. The client has a negative sputum culture
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b. The client tests negative for HIV
c. The client has a positive purified protein derivative test
d. The client's liver function test results are within the
expected reference range - ANSWER-a. The client has a
negative sputum culture
A client is caring for a client who develops an anaphylactic
reaction to IV administration. After assessing the client's
respiratory status and stopping the medication infusion.
Which of the following actions should the nurse take next?
a. Replace the infusion with 0.9% sodium chloride
b. Give diphenhydramine IM
c. Elevate the client's legs and feet
ATI Pharmacology Content Mastery Series Exam
2025/2026 Questions With 100% Detailed Answers
A nurse is caring for a client who has hyponatremia and is
receiving an infusion of a prescribed hypertonic solution.
Which of the following findings should indicate to the nurse
that the treatment is effective?
a. Absent Chvostek's sign
b. Improved cognition
c. Decreased vomiting
d. Cardiac arrhythmias absent - ANSWER-b. Improved
cognition
,2|Page
A nurse is teaching a client who has a new prescription for
a nitroglycerin transdermal patch. Which of the following
instructions should the nurse include?
a. "Discontinue the patch if you experience a headache."
b. "Apply a new patch if you have chest pain."
c. "Cover the patch with dry gauze when taking a shower."
d. "Remove the patch prior to going to bed." - ANSWER-d.
"Remove the patch prior to going to bed."
A nurse is reviewing he laboratory results of a client who
has a prescription for sodium polystyrene sulfonate
(Kayexalate) every 6 hr. which of the following should the
nurse report to the provider?
a. Creatinine 0.72 mg/dL
,3|Page
b. Sodium 138 mEq/L
c. Magnesium 2 mEq/L
d. Potassium 5.2 mEq/L - ANSWER-d. Potassium 5.2
mEq/L - Hyperkalemia (serum potassium level greater
than 5.0 mEq/L) increases the client risk for fatal cardiac
dysrhythmias. Kayexalate is used to decrease the serum
potassium level so the PN should monitor the client's
serum potassium level
A nurse is caring for a client who has tuberculosis and is
taking isoniazid and rifampin. Which of the following
outcomes indicates that the client is adhering to the
medication regimen?
a. The client has a negative sputum culture
, 4|Page
b. The client tests negative for HIV
c. The client has a positive purified protein derivative test
d. The client's liver function test results are within the
expected reference range - ANSWER-a. The client has a
negative sputum culture
A client is caring for a client who develops an anaphylactic
reaction to IV administration. After assessing the client's
respiratory status and stopping the medication infusion.
Which of the following actions should the nurse take next?
a. Replace the infusion with 0.9% sodium chloride
b. Give diphenhydramine IM
c. Elevate the client's legs and feet
