NSG 533 ADV PHARM MODULE 1
UPDATED EXAM WITH VERIFIED
SOLUTIONS.
Which drug class is most effective in treating erosive lesions:? -
correct answer -PPIs
Name 4 H2RAs: - correct answer -Cimetidine (Tagamet)
Famotidine (Pepcid)
Ranitidine (Zantac)
Nizatidine (Axid)
What is the action of H2RAs? - correct answer -Decrease acid
secretion by blocking histamine 2-receptors in gastric parietal
cells
Name 4 benefits of H2RAs - correct answer -1. Relieve GERD
symptoms
2. Can be administered prophylactically
3. More effective at controlling chronic GERD symptoms than
ANTACIDS
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4. Intermittent & routine dosing possible based on degree of
symptom control needed.
Name 2 drawbacks of H2RAs - correct answer -1. Less effective
in controlling chronic GERD symptoms than PPIs
2. Renal elimination may require dose adjustment in kidney
dysfunction patients
What are the side effects associated with H2RAs? - correct
answer -H/A, nausea (Cimetidine), weak inhibitor, common drug
interactions, gynecomastia, & Vit B-12 deficiency which affects
patients' tolerance
Name the benefits of Antacids - correct answer -1. Useful for
intermittent treatment of GERD symptoms
2. Immediate symptom relief
3. Usually well-tolerated
What are the drawbacks of Antacids? - correct answer -1.
Requires frequent dosing
2. Aluminum or Magnesium containing antacids may result in
electrolyte imbalances esp. in pts. w/renal impairment