PHARMACOLOGY Remediation (ADME; 12) EXAM UPDATED
ACTUAL EXAM COMPLETE QUESTIONS WITH DETAILED
VERIFIED ANSWERS (100% CORRECT ANSWERS)
/ALREADY GRADED A+
Define drug absorption.
Ans: Movement of drug into bloodstream after administration
Qiz Name some factors that affect drug absorption.
Ans: Dosage form
Route of administration
Qiz What is the difference between parenteral and enteral administration?
Ans: Parenteral does not involve GI tract, enteral does.
Qiz Describe intravenous administration.
,Ans: Parenteral
Used for rapid response
Bioavailibility = 100%
Not affected by diet
Drug administered IV cannot be "recalled"
Qiz Define intraarterial administration.
Ans: Parenteral
delivers drug directly to an artery that leads to target tissue
Qiz Define intrathecal administration.
Ans: Parenteral
used for drugs that need to be delivered to the brain
may be given as a lumbar puncture
Qiz Define intramuscular administration.
Ans: Parenteral
Injected into muscle
Absorption depends on volume injected/drug characteristics
Longer durations of administration
injection depot created
, Qiz Define subcutaneous administration.
Ans: Parenteral
injected into fatty tissue
application of heat/cold can affect absorption
Qiz Define oral administration.
Ans: Enteral
"swallowing pills"; most common ROA
subject to 1st pass metabolism
limited oral bioavailability
slow onset of action
Can irritate GI or be affected by diet
Qiz Define bioavailabilty.
Ans: The fraction of an administered dose that reaches systemic circulation.
Qiz Why is there a difference between the administered dose and that which reaches systemic
circulation?
Ans: 1st pass metabolism by the liver
ACTUAL EXAM COMPLETE QUESTIONS WITH DETAILED
VERIFIED ANSWERS (100% CORRECT ANSWERS)
/ALREADY GRADED A+
Define drug absorption.
Ans: Movement of drug into bloodstream after administration
Qiz Name some factors that affect drug absorption.
Ans: Dosage form
Route of administration
Qiz What is the difference between parenteral and enteral administration?
Ans: Parenteral does not involve GI tract, enteral does.
Qiz Describe intravenous administration.
,Ans: Parenteral
Used for rapid response
Bioavailibility = 100%
Not affected by diet
Drug administered IV cannot be "recalled"
Qiz Define intraarterial administration.
Ans: Parenteral
delivers drug directly to an artery that leads to target tissue
Qiz Define intrathecal administration.
Ans: Parenteral
used for drugs that need to be delivered to the brain
may be given as a lumbar puncture
Qiz Define intramuscular administration.
Ans: Parenteral
Injected into muscle
Absorption depends on volume injected/drug characteristics
Longer durations of administration
injection depot created
, Qiz Define subcutaneous administration.
Ans: Parenteral
injected into fatty tissue
application of heat/cold can affect absorption
Qiz Define oral administration.
Ans: Enteral
"swallowing pills"; most common ROA
subject to 1st pass metabolism
limited oral bioavailability
slow onset of action
Can irritate GI or be affected by diet
Qiz Define bioavailabilty.
Ans: The fraction of an administered dose that reaches systemic circulation.
Qiz Why is there a difference between the administered dose and that which reaches systemic
circulation?
Ans: 1st pass metabolism by the liver
