BOC Clinical Chemistry Review – Accurate
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Terms in this set (223)
FBS normal range 70-105mg/dl
Impaired fasting blood 100-125 mg/dl
glucose
Diabetic Ketoacidosis is glucosuria, ketones, dehydration, Kussmauls breathing
characterized by
HgB A1C normal value 2.2% -4.8%
HgB A1C good diabetic <6%
control
HgB A1C fair diabetic 6-8%
control
monitor glucose levels over a a 4-8 week period; useful
HgB A1C utilization
for assessing diet and medication compliance
shortened RBC lifespan of <120 days, hemolytic anemia,
HgB A1C affected by
hemoglobinopathies
Fructosamine special monitor 2-3 week glucose, rapid assessment diet
considerations changes
Fructosamine interference high levels of Vitamin C, hyperthyroidism
Pathways of glucose Embden-Meyerhof, Hexose Monophosphate Sunt,
metabolism Glycogenesis
Microalbuminuria use detects early signs of kidney malfunction
Causes elevated glucose Diabetes Mellitus, Cushings, Steroid use, Stress,
measurements Pheochromocytoma
Causes decreased glucose Insulin overdose, Addisons, sepsis
measurements
Osmolality measures total dissolved solutes in blood or urine
, Renal disease, Urinary obstruction,
Elevated BUN causes
dehydration,shock,infection,DM
Creatinine normal levels .6 - 1.2 mg/dl
BUN normal levels 10-20mg/dl
low GFR, poor perfusion of kidney,
pre-renal azotemia
dehydration,shock,CHF, fever,stress, severe burns
diminished GFR, associated with acute or chronic
renal azotemia
glomerulonephritis, polycystic kidney
Post renal azotemia result of obstruction, stones, enlarged prostate
Creatinine compared to Directly proportional to renal function and more
BUN reliable as single index of renal function
Creatinine clearance 107-139 ml/min
normal value
creatinine specimen 24 hour urine collection
GFR application or use best overall indicator of kidney function, normal >60
Uric acid normals less than 10mg/dl
Elevated Uric acid Gout, turnover of malignant cells, renal stones
pathologic findings
Total protein normal values normal 6.4-8.3 g/dl
hypoproteinemia etiology increased loss, decreased formation or intake
Elevated Total protein hemoconcentration, malignant tumor, multiple myeloma
causes
Decreased total protein nephrotic syndrome, severe liver disease, malabsortion
causes severe burns, diarrhea
Albumin Normal values 3.5 - 5.0 g/dl
Multiple myeloma also monoclonal gammopathy
known as
Multiple myeloma etiology malignant proliferation of plasma cells
Multiple myeloma lab increased ESR,RBC rouleaux, bence jones protein, M
findings spike in SPEP
Elevations in Troponin, total creatine kinase, CKMB
Cardiac markers
isoenzyme, and Myoglobin
Solutions For Every Question
Save
Terms in this set (223)
FBS normal range 70-105mg/dl
Impaired fasting blood 100-125 mg/dl
glucose
Diabetic Ketoacidosis is glucosuria, ketones, dehydration, Kussmauls breathing
characterized by
HgB A1C normal value 2.2% -4.8%
HgB A1C good diabetic <6%
control
HgB A1C fair diabetic 6-8%
control
monitor glucose levels over a a 4-8 week period; useful
HgB A1C utilization
for assessing diet and medication compliance
shortened RBC lifespan of <120 days, hemolytic anemia,
HgB A1C affected by
hemoglobinopathies
Fructosamine special monitor 2-3 week glucose, rapid assessment diet
considerations changes
Fructosamine interference high levels of Vitamin C, hyperthyroidism
Pathways of glucose Embden-Meyerhof, Hexose Monophosphate Sunt,
metabolism Glycogenesis
Microalbuminuria use detects early signs of kidney malfunction
Causes elevated glucose Diabetes Mellitus, Cushings, Steroid use, Stress,
measurements Pheochromocytoma
Causes decreased glucose Insulin overdose, Addisons, sepsis
measurements
Osmolality measures total dissolved solutes in blood or urine
, Renal disease, Urinary obstruction,
Elevated BUN causes
dehydration,shock,infection,DM
Creatinine normal levels .6 - 1.2 mg/dl
BUN normal levels 10-20mg/dl
low GFR, poor perfusion of kidney,
pre-renal azotemia
dehydration,shock,CHF, fever,stress, severe burns
diminished GFR, associated with acute or chronic
renal azotemia
glomerulonephritis, polycystic kidney
Post renal azotemia result of obstruction, stones, enlarged prostate
Creatinine compared to Directly proportional to renal function and more
BUN reliable as single index of renal function
Creatinine clearance 107-139 ml/min
normal value
creatinine specimen 24 hour urine collection
GFR application or use best overall indicator of kidney function, normal >60
Uric acid normals less than 10mg/dl
Elevated Uric acid Gout, turnover of malignant cells, renal stones
pathologic findings
Total protein normal values normal 6.4-8.3 g/dl
hypoproteinemia etiology increased loss, decreased formation or intake
Elevated Total protein hemoconcentration, malignant tumor, multiple myeloma
causes
Decreased total protein nephrotic syndrome, severe liver disease, malabsortion
causes severe burns, diarrhea
Albumin Normal values 3.5 - 5.0 g/dl
Multiple myeloma also monoclonal gammopathy
known as
Multiple myeloma etiology malignant proliferation of plasma cells
Multiple myeloma lab increased ESR,RBC rouleaux, bence jones protein, M
findings spike in SPEP
Elevations in Troponin, total creatine kinase, CKMB
Cardiac markers
isoenzyme, and Myoglobin
