MLS Hematology Exam Practice Questions & Study Guide | ASCP Certification Prep

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MLS HEMATOLOGY EXAM /HEMATOLOGY MLS

ACTUAL EXAM 400 QUESTIONS AND CORRECT

DETAILED ANSWERS WITH RATIONALES (VERIFIED

ANSWERS) |ALREADY GRADED A+

What is the first type of cell produced by the developing

embryo? .....ANSWER.....Erythrocyte

What percentage of tissue located in the bone marrow cavities

of adults is fat? .....ANSWER.....50%

Which of the following is not characteristic of pluripotent

hematopoietic stem cells? .....ANSWER.....Express the stem marker

CD13

In an adult, what are the two best areas for obtaining active

bone marrow by aspiration? .....ANSWER.....Posterior iliac crest,

sternum

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What is the normal ratio of myeloid to erythroid precursors in

bone marrow (M:E ratio)? .....ANSWER.....4:1

Which of the following does not accurately describe

hematopoietic growth factors? .....ANSWER.....Action of majority

is lineage restricted

In the third month of gestation, what is the primary site of

hematopoiesis? .....ANSWER.....Liver

The mechanism that relays information about tissue oxygen levels

to erythropoietin-producing sites is located in the:

.....ANSWER.....Kidney

Antigen-independent lymphopoiesis occurs in primary lymphoid

tissue located in the: .....ANSWER.....Thymus and bone marrow

Programmed cell death is called: .....ANSWER.....Apoptosis

In what area of the bone marrow does hematopoiesis take

place? .....ANSWER.....Cords

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Bone marrow cellularity refers to the ration of:

.....ANSWER.....Hematopoietic tissue to adipose tissue

Interleukins and colony stimulating factors are cytokines

produced by: .....ANSWER.....Monocytes and T lymphocytes

What is the approximate total blood volume in an adult?

.....ANSWER.....6 L

The myeloid progenitor cell can produce cells committed to:

.....ANSWER.....Granulocytic, erythrocytic, monocytic, or

megakaryocytic lineages

The largest hematopoietic cells in normal bone marrow are:

.....ANSWER.....Megakaryocytes

When evaluating a bone marrow aspirate smear, which finding is

considered abnormal? .....ANSWER.....The presence of 10%

myeloblasts on the cell differential count

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As most blood cell lines mature, which of the following is

characteristic? .....ANSWER.....Nucleus to cytoplasm ratio (N:C)

decreases

Which of the following describes thrombopoietin (TPO)?

.....ANSWER.....Hormone produced by the liver that stimulates

megakaryopoiesis

When the hepatic phase of fetal life is reactivated in an adult,

hematopoiesis can be termed: .....ANSWER.....Myeloid

metaplasia or extramedullary

What is the average life span of a normal red blood cell?

.....ANSWER.....120 days

The Na+-K+ cation pump is an important mechanism in keeping

the red blood cell intact. Its function is to maintain a high level of:

.....ANSWER.....Intracellular K+

Which of the following depicts the structure of the hemoglobin

molecule? .....ANSWER.....Four heme groups, four globin chains