PEBC Evaluating Exam 2025: 2 Versions, 150 Questions & Verified Answer Explanations

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PEBC EVALUATING 2025 NEWEST EXAM 2 VERSIONS

WITH 150 QUESTIONS WITH DETAILED VERIFIED

ANSWERS (100% CORRECT) /ALREADY GRADED A+



Time it takes for amount of drug to fall to half of its value,

constant in first order kinetics (majority of drugs)

.....ANSWER.....Half-life (T1/2)

Inducers of Cytochrome P450 (CYP450) (4)

.....ANSWER.....Barbiturates

Phenytoin

Carbamazepine

Rifampin

Inhibitors of CYP450 .....ANSWER.....Cimetidine

Ketoconazole

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Erythromycin

Isoniazid

Grapefruit

Their MOA utilizes intracellular receptors: .....ANSWER.....Thyroid

and steroid hormones

This compound's MOA utilizes transmembrane receptors:

.....ANSWER.....Insulin

Antidote used for organophosphate/anticholinesterase

.....ANSWER.....Atropine, pralidoxime (2-PAM)

Antidote used for acetaminophen (APAP) toxicity

.....ANSWER.....N-acetylcysteine

Antidote used for heparin toxicity .....ANSWER.....Protamine

Sulfate

Antidote used for warfarin toxicity .....ANSWER.....Vitamin K and

Fresh frozen plasma (FFP)

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Antidote for tissue plasminogen activator (t-PA), streptokinase

.....ANSWER.....Aminocaproic acid

Antidote used for opioid toxicity .....ANSWER.....Naloxone (IV),

naltrexone (PO)

Antidote used for benzodiazepine toxicity

.....ANSWER.....Flumazenil

Interaction with this drug requires dose reduction of 6-MP(6-

mercaptopurine) .....ANSWER.....Allopurinol

May protect against doxorubicin cardio-toxicity by chelating iron

.....ANSWER.....Dexrazoxane

Blows DNA (breaks DNA strands), limiting SE is pulmonary

fibrosis .....ANSWER.....Bleomycin

Binds tubulin and prevents the disassembly of microtubules during

the M phase of the cell cycle inducing mitotic arrest

.....ANSWER.....Paclitaxel (taxol)

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Anti-estrogen used for estrogen receptor + breast cancer

.....ANSWER.....Tamoxifen

Anti-emetics used in association with anti-cancer drugs that are

5-HT3 (serotonin receptor subtype ) antagonist

.....ANSWER.....Odansetron

Granisetron

Dolasetron

Palonosetron

Hormone inhibiting prolactin release .....ANSWER.....Dopamine

ACTH analog used for diagnosis of patients with corticosteroid

abnormality .....ANSWER.....Cosyntropin

Synthetic analog of ADH hormone used for diabetes insipidus

and nocturnal enuresis .....ANSWER.....Desmopressin (DDAVP)

Most widely used thyroid drugs such as Synthroid and Levoxyl

contain .....ANSWER.....L-thyroxine (T4)