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Pediatric COMAT Exam Guide: Study Tips, Content Outline & High-Yield Review

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A comprehensive guide to preparing for the Pediatric COMAT clinical exam. This PDF covers the core content outline, key diagnoses, study strategies, and high-yield topics to help osteopathic medical students succeed.

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Pediatric Comat Exam Newest 2025/2026 With
Complete 150 Questions And Correct Answers
|Already Graded A+||Brand New Version!|



___ mental retardation, autistic-like behavior, abnormal
facies (long face, large ears). More common in males
and when present in females usually milder. X-linked
dominant with variable penetrance. -
...ANSWER...✔✔*Fragile X* -> CGG repeat FMR1
region X chromosome
- Mitral valve prolapse
- Macroorchidism


Pt has HTN, hypokalemia, hypernatremia, metabolic
alkalosis with LOW aldosterone ___ diagnosis. -
...ANSWER...✔✔*Liddle syndrome*
- AD incidental finding HTN child
- Genetic mutation epithelial sodium channel (ENaC) in
the distal tubule
- Tx: Amiloride


__ syndrome AR presents in childhood and hypokalemia
and metabolic alkalosis due to primary defect in sodium
chloride (Na/K/Cl-) reabsorption in medullary thick

,2|Page


ascending limb of loop of Henle. -
...ANSWER...✔✔*Bartter syndrome*
- low to normal blood pressure
- hypercalciuria


___ is a disorder of children that causes inability to
absorb sufficient zinc. It causes impaired would healing
and erythematous pustular dermatitis. -
...ANSWER...✔✔*Acrodermatitis Enteropathica*


___ result in an absent Moro reflex on the affected side,
along with spasm of the SCM in a LGA baby. -
...ANSWER...✔✔*Clavicle fracture*
- child unable to move the IL arm, crepitus or bony
irregularities are present
- tx: immobilization pinning child's sleeve to their chest
- most fractures heal w/in 7-10 days w/o long-term
complications


First line tx neonatal hypoglycemia as complication
diabetic pregnancy. - ...ANSWER...✔✔5% or 10%
dextrose drip for several days until hyperinsulinemia
resolves

,3|Page


Signs: hypotonia, jitteriness, lethargy, poor feeding,
seizures


Tx grade III spondylolisthesis 50-75% slippage. -
...ANSWER...✔✔Tx medically *custom orthotic bracing
for 6-8 weeks*
- gentle indirect manipulation applied to surrounding
structures
- avoid direct techniques + manipulation lumbar spine


__ and __ nerves are important in sucking and feeding
for the newborn infant. Cranial SD can affect baby's
ability to breastfeed. -
...ANSWER...✔✔*Glossopharyngeal n*. (jugular
foramen compression)
- taste posterior 2/3 tongue, swallowing, salivation,
chemo + baro carotid sinus + body


*Hypoglossal n.* (hypoglossal canal)


CSF finding mildly elevated protein, normal glucose,
and elevated mononuclear cells consistent with __
meningitis. - ...ANSWER...✔✔*VIRAL*
- HSV (nonspecific symptoms)

, 4|Page


- Prompt tx acyclovir since infection can lead to severe
neuro damage + death


3 year old male has frequent episodes sinusitis and
pneumonia, dilated tortuous vessels in the conjunctiva,
ataxia. - ...ANSWER...✔✔*Ataxia-telangiectasia*
- ataxia, telangiectasia (skin + eyes), recurrent
sinopulmonary infections
- *undetectable IgA w/ elevated IgM* + normal IgG


___ present first 24 hours of life with failure to pass
meconium. Dx is made by ___. -
...ANSWER...✔✔*Hirschsprung's disease*
- *rectal biopsy* shows absence of ganglion cells
- sample 2 cm above dentate line to avoid sampling
normal transition from ganglionated bowel to the
absence of ganglia in internal sphincter


Infants with ___ become symptomatic soon after birth
with excessive secretions, respiratory distress, and
inability to feed. Passage of a catheter into the stomach
may be difficult and CXR will reveal catheter curled in
the upper esophageal pouch. -
...ANSWER...✔✔*Tracheoesophageal fistula +
esophageal atresia*

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