1|Page
Comprehensive PN Adult Medical-Surgical Content
Mastery Series (CMS) Exam 2025 – Study Guide, Practice
Questions, and Rationales for PN Students
Prepare for the PN Adult Medical-Surgical CMS Exam 2025 with study guides, ATI-style
practice questions, rationales, and key concepts for LPN/LVN success.
Get ready for the Comprehensive PN Adult Medical-Surgical Content Mastery Series
(CMS) Exam 2025 with this all-in-one nursing study guide. Review essential topics in adult
medical-surgical nursing, including cardiovascular, respiratory, endocrine, renal,
musculoskeletal, and neurological systems. Includes ATI-style CMS exam practice questions,
rationales, and evidence-based study tips to improve your performance and boost your CMS
and predictor scores. Perfect for PN, LPN, and LVN students preparing for ATI CMS exams or
NCLEX-PN readiness assessments.
• PN adult medical-surgical CMS exam 2025
• comprehensive PN CMS exam study guide
• ATI PN medical-surgical CMS exam questions and answers
• PN CMS exam ATI practice test pdf
TEST
A nurse is prioritizing care for four clients following a change-of-shift report. Which of the following
clients should the nurse attend to first?
a) A client who has diverticulitis and a
temperature of 38.3C (100.9F)
,2|Page
b) A client who has a prescription for a sputum
specimen to be obtained before breakfast
c) A client who sustained a head injury 2 days
ago and has a decreased level of
consciousness
d) A client who has Alzheimer's disease and
requires assistance to the bathroom - ANSWER-C. A client who sustained a head injury 2 days ago and
has a decreased level of consciousness.
Rationale:
The decrease level of consciousness needs immediate action and monitoring. This could lead to deficit
level of brain functioning that may lead to shock thus needing intensive care. Having a febrile client as
what option 1 presents also needs attention however fever is also included in the symptoms of
infected/inflamed diverticula. Though significant but the value given is manageable range.
A nurse is reinforcing teaching about immunizations with an older adult client. Which of the following
instructions should the nurse include?
a) "You should receive the live, attenuated influenza vaccine every other year."
b) "You should receive the hepatitis A vaccine
every 10 years."
c) "You should receive the human
papillomavirus vaccine."
d) "You should receive one dose of the pneumococcal vaccine." - ANSWER-D. "You should receive one
dose of the pneumococcal vaccine."
Rationale:
,3|Page
One dose Pneumococcal vaccine is given to elderly 65 yrs old above. Influenza vaccine is given annually
to this age group. HPV is given to women in reproductive age.
TEST
A nurse is monitoring a client who is receiving a transfusion of packed RBCs. Which of the following
findings should the nurse identify as an indication that the client should receive diphenhydramine?
a) Pulmonary congestion
b) Urticaria
c) Vomiting
d) Jugular vein distention - ANSWER-B. Urticaria
Rationale:
Acute hypersensitivity reaction following blood transfusion includes symptoms of localized pruritus and
urticaria unrelated to infusion site. Diphenhydramine is an antihistamine use to treat hypersensitivity or
allergic reaction.
TEST
A nurse is caring for a client who is expecting a generalized tonic-clonic seizure. Which of the following
actions should the nurse take?
a) Apply restraints to the client.
b) Insert a tongue blade into the client's mouth.
c) Administer an IV bolus of lorazepam.
d) Place the client in the prone position. - ANSWER-c) Administer an IV bolus of lorazepam
Rationale:
Administering an IV bolus of lorazepam is the appropriate action for a patient who is expecting a
generalized tonic-clonic seizure, as it can help prevent or reduce the severity of the seizure.
, 4|Page
A nurse in a long-term care unit is assisting in the care of a client who has Alzheimer's disease. Which of
the following actions should the nurse take?
A. Alternate the client's daily routine
B. Keep the lights dimmed.
C. Raise the four side rails on the client's bed.
D. Participate in reminiscence therapy with the client. - ANSWER-D. Participate in reminiscence therapy
with the client.
TEST
A nurse is reinforcing teaching with a client who is taking oxybutynin. The nurse should tell the client
that the medication will have which of the following effects?
a) Relaxes the muscles of the bladder
b) Increases venous return to the heart
c) Relaxes the muscles of the colon
d) Increases tissue perfusion in the lungs - ANSWER-A. Relaxes the muscles of the bladder.
Rationale:
Oxybutynin relaxes the bladder muscles to decrease the urge of constant urination.
Option B does not increase or promote venous return.
Option C the bladder is the target organ not the colon.
Option D not associated with increased blood flow and perfusion to lungs.
TEST
Comprehensive PN Adult Medical-Surgical Content
Mastery Series (CMS) Exam 2025 – Study Guide, Practice
Questions, and Rationales for PN Students
Prepare for the PN Adult Medical-Surgical CMS Exam 2025 with study guides, ATI-style
practice questions, rationales, and key concepts for LPN/LVN success.
Get ready for the Comprehensive PN Adult Medical-Surgical Content Mastery Series
(CMS) Exam 2025 with this all-in-one nursing study guide. Review essential topics in adult
medical-surgical nursing, including cardiovascular, respiratory, endocrine, renal,
musculoskeletal, and neurological systems. Includes ATI-style CMS exam practice questions,
rationales, and evidence-based study tips to improve your performance and boost your CMS
and predictor scores. Perfect for PN, LPN, and LVN students preparing for ATI CMS exams or
NCLEX-PN readiness assessments.
• PN adult medical-surgical CMS exam 2025
• comprehensive PN CMS exam study guide
• ATI PN medical-surgical CMS exam questions and answers
• PN CMS exam ATI practice test pdf
TEST
A nurse is prioritizing care for four clients following a change-of-shift report. Which of the following
clients should the nurse attend to first?
a) A client who has diverticulitis and a
temperature of 38.3C (100.9F)
,2|Page
b) A client who has a prescription for a sputum
specimen to be obtained before breakfast
c) A client who sustained a head injury 2 days
ago and has a decreased level of
consciousness
d) A client who has Alzheimer's disease and
requires assistance to the bathroom - ANSWER-C. A client who sustained a head injury 2 days ago and
has a decreased level of consciousness.
Rationale:
The decrease level of consciousness needs immediate action and monitoring. This could lead to deficit
level of brain functioning that may lead to shock thus needing intensive care. Having a febrile client as
what option 1 presents also needs attention however fever is also included in the symptoms of
infected/inflamed diverticula. Though significant but the value given is manageable range.
A nurse is reinforcing teaching about immunizations with an older adult client. Which of the following
instructions should the nurse include?
a) "You should receive the live, attenuated influenza vaccine every other year."
b) "You should receive the hepatitis A vaccine
every 10 years."
c) "You should receive the human
papillomavirus vaccine."
d) "You should receive one dose of the pneumococcal vaccine." - ANSWER-D. "You should receive one
dose of the pneumococcal vaccine."
Rationale:
,3|Page
One dose Pneumococcal vaccine is given to elderly 65 yrs old above. Influenza vaccine is given annually
to this age group. HPV is given to women in reproductive age.
TEST
A nurse is monitoring a client who is receiving a transfusion of packed RBCs. Which of the following
findings should the nurse identify as an indication that the client should receive diphenhydramine?
a) Pulmonary congestion
b) Urticaria
c) Vomiting
d) Jugular vein distention - ANSWER-B. Urticaria
Rationale:
Acute hypersensitivity reaction following blood transfusion includes symptoms of localized pruritus and
urticaria unrelated to infusion site. Diphenhydramine is an antihistamine use to treat hypersensitivity or
allergic reaction.
TEST
A nurse is caring for a client who is expecting a generalized tonic-clonic seizure. Which of the following
actions should the nurse take?
a) Apply restraints to the client.
b) Insert a tongue blade into the client's mouth.
c) Administer an IV bolus of lorazepam.
d) Place the client in the prone position. - ANSWER-c) Administer an IV bolus of lorazepam
Rationale:
Administering an IV bolus of lorazepam is the appropriate action for a patient who is expecting a
generalized tonic-clonic seizure, as it can help prevent or reduce the severity of the seizure.
, 4|Page
A nurse in a long-term care unit is assisting in the care of a client who has Alzheimer's disease. Which of
the following actions should the nurse take?
A. Alternate the client's daily routine
B. Keep the lights dimmed.
C. Raise the four side rails on the client's bed.
D. Participate in reminiscence therapy with the client. - ANSWER-D. Participate in reminiscence therapy
with the client.
TEST
A nurse is reinforcing teaching with a client who is taking oxybutynin. The nurse should tell the client
that the medication will have which of the following effects?
a) Relaxes the muscles of the bladder
b) Increases venous return to the heart
c) Relaxes the muscles of the colon
d) Increases tissue perfusion in the lungs - ANSWER-A. Relaxes the muscles of the bladder.
Rationale:
Oxybutynin relaxes the bladder muscles to decrease the urge of constant urination.
Option B does not increase or promote venous return.
Option C the bladder is the target organ not the colon.
Option D not associated with increased blood flow and perfusion to lungs.
TEST
