University Of Alabama Nur 529 Exam 3
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What percentage of erythropoietin is produced by the
kidney? - . . ANSWER ✔ ✔Approximately 90%
What percentage of erythropoietin is produced by the liver
and other organs? - . . ANSWER ✔ ✔Approximately 10%
How does kidney dysfunction affect red blood cell
development? - . . ANSWER ✔ ✔It impacts RBC
development and availability.
What deficiencies may contribute to anemia in chronic
kidney disease (CKD)? - . . ANSWER ✔ ✔Vitamin B12,
iron, and folate deficiencies.
What is the hemoglobin level that defines chronic anemia
in adult males? - . . ANSWER ✔ ✔Less than 13.0 g/dL
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What is the hemoglobin level that defines chronic anemia
in adult females? - . . ANSWER ✔ ✔Less than 12 g/dL
What is the most profound hematologic alteration that
accompanies chronic kidney disease (CKD)? - . . ANSWER
✔ ✔Chronic anemia
What is the association between GFR decline and
hematocrit in advanced CKD in African Americans? - . .
ANSWER ✔ ✔Research shows an association between
GFR decline and the decline in hematocrit.
What do NKF guidelines recommend for individuals with a
GFR less than 60 mL/min/1.73 m2? - . . ANSWER ✔
✔They should be evaluated for anemia.
What measures are included in the assessment for anemia
in CKD? - . . ANSWER ✔ ✔Measures of hemoglobin,
hematocrit, and iron stores.
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What are some factors contributing to anemia in CKD? - . .
ANSWER ✔ ✔Chronic blood loss, hemolysis, bone
marrow suppression, and decreased red cell production.
Why is erythropoietin production usually insufficient in
kidney failure? - . . ANSWER ✔ ✔It is insufficient to
stimulate adequate red blood cell production by the bone
marrow.
What are some causes of iron deficiency in people with
CKD? - . . ANSWER ✔ ✔Anorexia, dietary restrictions,
and blood loss during dialysis.
What is the major metabolic function of colonic
microorganisms? - . . ANSWER ✔ ✔The fermentation of
undigestible dietary residue and endogenous mucus.
What is a major source of energy in the colon? - . .
ANSWER ✔ ✔Fermentation of nondigestible
carbohydrates, including resistant starches, cellulose,
pectins, and unabsorbed sugars.
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What role do colonic microorganisms play in vitamin
synthesis? - . . ANSWER ✔ ✔They synthesize vitamin K.
Why do newborn infants not synthesize adequate amounts
of vitamin K initially? - . . ANSWER ✔ ✔Because the
normal colonic bacterial flora has not yet become
established.
What protective role does the resident gut flora provide? - .
. ANSWER ✔ ✔It provides a crucial line of resistance to
colonization by exogenous microbes.
What can disrupt the microbial balance in the gut? - . .
ANSWER ✔ ✔The administration of broad-spectrum
antibiotics.
What is the role of probiotics? - . . ANSWER ✔ ✔They are
live microorganisms that can modify the composition of
enteric flora when ingested.
What are some commonly used probiotics? - . . ANSWER
✔ ✔Lactobacilli, bifidobacteria, and nonpathogenic
Escherichia coli.