Maryville Pharm Exam 4 | STUDY GUIDE
Terms in this set (163)
management/maintenance of COPD (chronic bronchitis and
Tiotriopium use
emphysema); NOT for acute exacerbations
Non-selective muscarinic receptor antagonist; or anti-
Tiotropium mech of action muscarinic/anticholinergic. Acts mainly on M3 receptors
located on the smooth muscle cells and submucosal cells
Spiriva Tiotropium brand name
Singulair Montelukast brand name
Skin rash
Mood changes: of anxiety, aggression, depression, and or
suicidal thoughts can occur
Tremors
Headache
Montelukast adverse effects GI: stomach pain, heartburn, upset
stomach, N/D Sore throat, stuffy
nose, cough, hoarseness Tooth
pain
Tiredness
Montelukast drug interactions Phenobarbital and rifampin
, Not for asthma attacks; not for exercise induced bronchoconstriction.
Call prescriber for mood/behavior changes: anxiety,
depression, thoughts of suicide/self-harm
Montelukast patient teaching May take several weeks to take
full effect Follow label
directions
Notify prescriber re any deterioration in asthma sx
Take twice a day, every day for
Inhaled corticosteroid pt
prevention of asthma Rinse mouth after
teaching
use to prevent thrush
Long-acting Beta agonist African Americans have increased incidence of death with this
contraindicated for category of meds
, Ipratropium Prescribed for bronchospasm with use of propranolol
Relaxes bronchial smooth muscle by action on the beta 2
Mech of action for albuterol
receptors with little effect on heart rate, causing dilation
of airways
Extremely potent vasoconstrictive and anti-
inflammatory activity Increase peak flow
readings.
Decrease airway hyperresponsiveness
Inhibits the immunoglobulin E (IgE) and mas cell-mediated
Mech of action of inhaled migration of inflammatory cells into the bronchial tissue
corticosteroids (late-phase allergic reaction).
Exact mechanism of action on bronchoconstriction and
production of smooth muscle relaxation and nasal
mucosa is unknown.
Intranasal applied topically in the nasal tissue exert anti-
inflammatory effects Allergic rhinitis and asthma - the
primary action is anti-inflammatory.
Drug of choice for acute treatment of asthma sx
and exacerbations Relax bronchospasms (tight
Short-acting Beta agonist use band)
Doesn't control inflammation
Shouldn't be needed more than 2x/week
Prevents the effects of ACh by competitively blocking its
Inhaled
binding to muscarinic receptors in the CNS, peripheral
anti-muscarinics/anticholiner
ganglia and at neuroeffector sites on the smooth muscle,
gics MOA
cardiac muscle and secretory glands.
Prototype of muscarinic Atropine
Terms in this set (163)
management/maintenance of COPD (chronic bronchitis and
Tiotriopium use
emphysema); NOT for acute exacerbations
Non-selective muscarinic receptor antagonist; or anti-
Tiotropium mech of action muscarinic/anticholinergic. Acts mainly on M3 receptors
located on the smooth muscle cells and submucosal cells
Spiriva Tiotropium brand name
Singulair Montelukast brand name
Skin rash
Mood changes: of anxiety, aggression, depression, and or
suicidal thoughts can occur
Tremors
Headache
Montelukast adverse effects GI: stomach pain, heartburn, upset
stomach, N/D Sore throat, stuffy
nose, cough, hoarseness Tooth
pain
Tiredness
Montelukast drug interactions Phenobarbital and rifampin
, Not for asthma attacks; not for exercise induced bronchoconstriction.
Call prescriber for mood/behavior changes: anxiety,
depression, thoughts of suicide/self-harm
Montelukast patient teaching May take several weeks to take
full effect Follow label
directions
Notify prescriber re any deterioration in asthma sx
Take twice a day, every day for
Inhaled corticosteroid pt
prevention of asthma Rinse mouth after
teaching
use to prevent thrush
Long-acting Beta agonist African Americans have increased incidence of death with this
contraindicated for category of meds
, Ipratropium Prescribed for bronchospasm with use of propranolol
Relaxes bronchial smooth muscle by action on the beta 2
Mech of action for albuterol
receptors with little effect on heart rate, causing dilation
of airways
Extremely potent vasoconstrictive and anti-
inflammatory activity Increase peak flow
readings.
Decrease airway hyperresponsiveness
Inhibits the immunoglobulin E (IgE) and mas cell-mediated
Mech of action of inhaled migration of inflammatory cells into the bronchial tissue
corticosteroids (late-phase allergic reaction).
Exact mechanism of action on bronchoconstriction and
production of smooth muscle relaxation and nasal
mucosa is unknown.
Intranasal applied topically in the nasal tissue exert anti-
inflammatory effects Allergic rhinitis and asthma - the
primary action is anti-inflammatory.
Drug of choice for acute treatment of asthma sx
and exacerbations Relax bronchospasms (tight
Short-acting Beta agonist use band)
Doesn't control inflammation
Shouldn't be needed more than 2x/week
Prevents the effects of ACh by competitively blocking its
Inhaled
binding to muscarinic receptors in the CNS, peripheral
anti-muscarinics/anticholiner
ganglia and at neuroeffector sites on the smooth muscle,
gics MOA
cardiac muscle and secretory glands.
Prototype of muscarinic Atropine
