ABPN MOC Board Exam review 2026
Questions and Answers
1A2, ciprofloxacin increases it's levels, it increases theophylline and Haldol levels
- Correct answer-Fluvoxamine is metabolized through which CYT P450 enzyme?
What increases it? What drug levels does it increase.
2C19 - Correct answer-Citalopram is metabolized throught which CYT P450
enzyme?
2D6, metabolizes TCAs - Correct answer-Fluoxetine, fluvoxamine and paroxetine
as well as bupropion are metabolized through which CYT P450 enzyme?
3A4 - Correct answer-Sertraline is metabolized through which CYT P450 enzyme?
Distractibility, Increased goal-directed activity, Grandiosity, Flight of ideas (racing
thoughts), Activities with a potential for consequences, Sleep decreased,
Talkativeness - Correct answer-What does DIGFAST stand for when you describe
symptoms of mania or hypomania?
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,Count all mood episodes (depressed, hypomanic, manic); 4 mood episodes per
year, more common in women. - Correct answer-What is the definition of rapid
cycling?
VPA (valproic acid) better than lithium - Correct answer-Which traditional mood
stabilizer does rapid cycling respond best to?
Sleep disturbance, Interest decreased, Guilt, Energy loss (fatigue), Concentration
decreased, Appetite changes, Psychomotor changes, Suicidal ideation - Correct
answer-What does SIGECAPS stand for in depression?
Kleine-Levin Syndrome - Correct answer-What is referred to as "sleeping beauty
syndrome?" It is rare, more common in adolescent males and causes extreme
hypersomnolence, hyperphagia, hypersexuality and may have a viral correlation. It
may also be secondary to bipolar disorder; lithium helps decrease the frequency
and intensity of symptoms.
Lithium and Clozaril - Correct answer-What 2 medications decrease the risk of
suicide?
Quetiapine (Seroquel), ludisarone (Latuda) and Symbiax - Correct answer-What 3
meds are FDA approved for bipolar depression?
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, AROLL, Aripiprazole, Risperdal Consta, Olanzepine, Lithium, Lamictal - Correct
answer-What meds are indicated for bipolar maintenence? (remember pneumonic)
Amilioride - Correct answer-How do you treat diabetes insipidus caused by
lithium?
PCOS, hepatotoxicity, thrombocytopenia, hemorrhagic pancreatitis. - Correct
answer-What are 4 serious side effects of VPA?
Toxic epidermal necrolysis - Correct answer-What is the black box warning for
CBZ?
6 months - Correct answer-How long must symptoms be present to diagnose an
individual with generalized anxiety disorder?
50 - 70% - Correct answer-What percentages of persons with borderline
personality disorder (BPD) are estimated to have been victims of sexual and
physical abuse?
Phenobarbital - Correct answer-Acidification of urine is contraindicated in the
management of intoxication with which one of the following drugs?
3 months - Correct answer-Abruptly stopping lithium in patients with bipolar
disorder is associated with increased risk of relapse. What is the recommended
length of the taper off lithium?
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Questions and Answers
1A2, ciprofloxacin increases it's levels, it increases theophylline and Haldol levels
- Correct answer-Fluvoxamine is metabolized through which CYT P450 enzyme?
What increases it? What drug levels does it increase.
2C19 - Correct answer-Citalopram is metabolized throught which CYT P450
enzyme?
2D6, metabolizes TCAs - Correct answer-Fluoxetine, fluvoxamine and paroxetine
as well as bupropion are metabolized through which CYT P450 enzyme?
3A4 - Correct answer-Sertraline is metabolized through which CYT P450 enzyme?
Distractibility, Increased goal-directed activity, Grandiosity, Flight of ideas (racing
thoughts), Activities with a potential for consequences, Sleep decreased,
Talkativeness - Correct answer-What does DIGFAST stand for when you describe
symptoms of mania or hypomania?
©COPYRIGHT 2025, ALL RIGHTS RESERVED 1
,Count all mood episodes (depressed, hypomanic, manic); 4 mood episodes per
year, more common in women. - Correct answer-What is the definition of rapid
cycling?
VPA (valproic acid) better than lithium - Correct answer-Which traditional mood
stabilizer does rapid cycling respond best to?
Sleep disturbance, Interest decreased, Guilt, Energy loss (fatigue), Concentration
decreased, Appetite changes, Psychomotor changes, Suicidal ideation - Correct
answer-What does SIGECAPS stand for in depression?
Kleine-Levin Syndrome - Correct answer-What is referred to as "sleeping beauty
syndrome?" It is rare, more common in adolescent males and causes extreme
hypersomnolence, hyperphagia, hypersexuality and may have a viral correlation. It
may also be secondary to bipolar disorder; lithium helps decrease the frequency
and intensity of symptoms.
Lithium and Clozaril - Correct answer-What 2 medications decrease the risk of
suicide?
Quetiapine (Seroquel), ludisarone (Latuda) and Symbiax - Correct answer-What 3
meds are FDA approved for bipolar depression?
©COPYRIGHT 2025, ALL RIGHTS RESERVED 2
, AROLL, Aripiprazole, Risperdal Consta, Olanzepine, Lithium, Lamictal - Correct
answer-What meds are indicated for bipolar maintenence? (remember pneumonic)
Amilioride - Correct answer-How do you treat diabetes insipidus caused by
lithium?
PCOS, hepatotoxicity, thrombocytopenia, hemorrhagic pancreatitis. - Correct
answer-What are 4 serious side effects of VPA?
Toxic epidermal necrolysis - Correct answer-What is the black box warning for
CBZ?
6 months - Correct answer-How long must symptoms be present to diagnose an
individual with generalized anxiety disorder?
50 - 70% - Correct answer-What percentages of persons with borderline
personality disorder (BPD) are estimated to have been victims of sexual and
physical abuse?
Phenobarbital - Correct answer-Acidification of urine is contraindicated in the
management of intoxication with which one of the following drugs?
3 months - Correct answer-Abruptly stopping lithium in patients with bipolar
disorder is associated with increased risk of relapse. What is the recommended
length of the taper off lithium?
©COPYRIGHT 2025, ALL RIGHTS RESERVED 3
