CBNS 121 LECTURES 14 & 15 QUESTIONS AND ANSWERS GRADED A+

CBNS 121 LECTURES 14 & 15 QUESTIONS AND ANSWERS GRADED A+ ______ is mediated by an ___________ in calcium concentration in the _______ _____________ cell - Answers LTP Increase Post synaptic ______ is a smaller ________ in postsynaptic calcium concentration, accompanied by a ____________ in the number and sensitivity of post synaptic ____________ - Answers LTD Increase Reduction Receptors Sensitizing repetitively is known as: - Answers Facilitation LTD and LTP are associated with: - Answers Memory What is synaptic facilitation? - Answers Increase in synaptic strength that results when action potentials occur in rapid succession The amplitude of the postsynaptic potential may increase which is known as ________________ - Answers Facilitation When vesicles are getting depleted, this is known as ___________ - Answers Depression There are three forms of short term plasticity: - Answers Facilitation, augmentation and PTP Transmitter release can be subject to synaptic _____________ if the number of ____________ released by stimuli is __________ - Answers Depression Quanta Large What is tetanus? - Answers Long high frequency of stimuli Tetanus can result in synaptic _____________ - Answers Depression post-tetanic potentiation (PTP): - Answers An increase in the rate of spontaneous transmitter release from the nerve terminal Augmentation: - Answers Enhancement of transmitter release by repetitive stimulation augmentation is ____________ than facilitation - Answers Slower Augmentation and facilitation can result in an increase in synaptic potential ______________. - Answers Amplitude Facilitation, depression, augmentation, and PTP are: - Answers Short term changes in synaptic efficiency Short term changes in synaptic efficiency is due to the ______________ or _______________ in the number of __________ transmitter released from presynaptic terminals. - Answers Increase Decrease Quanta Fractional release is dependent on the amount of ____________ that enters the terminal through ___________ ____________ channels - Answers Calcium Voltage gated More calcium means more ____________ release - Answers Transmitter _____________ is related to increasing calcium left over from the previous stimuli. The ___________ amounts trigger __________, this increases the probability of increased cytoplasmic calcium contributing to facilitation. - Answers Facilitation Residual Release After a stimulus is applied after 2-3 times, the probability of transmitter release starts to _______________ - Answers Decrease _____________ of synaptic potential is seen only after a __________ ____________ release, and depletion of _____________ from the nerve terminal. - Answers Depression Large quantal Vesicles Large quantal release has a large ____________ entry, so calcium may contribute in _____________ in calcium current - Answers Calcium Reduction Different neurons have differing ______ _____________ - Answers Gene expressions Short term sensitization: - Answers a form of sensitization that lasts a relatively short period of time long term sensitization: - Answers A form of sensitization that is persistent or slow to