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BMTCN TESTBANK EXAM A&B ALL COMPLETE 500
QUESTIONS AND CORRECT AND RATIONALES
SOLUTIONS JUST RELEASED THIS YEAR
Question: Which of the following drugs will most likely lead to heart failure as being used in the
conditioning regimen?
A. Busulfan
B. Cytarabine
C. Fludarabine
D. Cyclophosphamide - CORRECT ANSWER✔✔D. Cyclophosphamide
Explanation: Cardiac toxicity is the result of harmful chemicals causing damage to the heart.
Toxins (drugs) may be administered to you as part of your treatment to destroy cancer cells.
Normal cells in and around your heart can also be killed as a side effect. Patients taking a
cumulative dose of more than 150mg/kg cyclophosphamide have a 7-33% chance of developing
acute heart failure. Depending on the dosing regimen and patient population, fatal
cyclophosphamide cardiomyopathy can range from 2 to 17%.
Question: Daisy has leukemia. She will require HSCT treatment. In this situation, which of the
following is the most important thing for the nurse to consider while teaching her caregiver?
A. Request that the teaching be done by a nurse who is not caring for the patient
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B. Discuss the probability of transferring the details to someone other than the caregiver
C. Concentrate on details about the present stage of treatment
D. Keep track of the caregiver's emotional reaction - CORRECT ANSWER✔✔C. Concentrate on
details about the present stage of treatment
Explanation: A successful caregiver must have the ability to develop adequate coping strategies,
solve problems, and prioritize. To be able to offer adequate treatment for an HSCT recipient, the
caregiver must preserve his or her own quality of life -- including mental, physical, and
emotional health -- during the transplanting phase. Since the conditions of patients and their
caregivers change with each phase of treatment, it's critical to customize teaching to the
particular phase of treatment.
Question: Under utilization for certain diseases occurs due to transplant-related toxicity. For
which of the following disease is transplant-related toxicity a barrier?
A. Neuroblastoma
B. Arrhythmia
C. Acute Myeloid Leukemia
D. Sickle Cell Disease - CORRECT ANSWER✔✔D. Sickle Cell Disease
Explanation: While the clinical course of sickle cell disease (SCD) varies, many patients
experience end-organ complications that are associated with severe morbidity and mortality.
While myeloablative allogeneic HSCT (allo-HSCT) is curative, it has traditionally been reserved
for children under the age of 16. Sickle cell disease (SCD) is triggered by a single nucleotide
mutation in the -globin protein, which replaces glutamate with valine in the 6th spot. The
hemoglobin protein is more likely to polymerize when deoxygenated as a result of this
transition, resulting in sickle-shaped red cells.
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Question: Identify which among the following electrolyte abnormalities, is not characterized as
an acute tumor lysis syndrome?
A. Hypocalcemia
B. Hyperkalemia
C. Hyperuricermia
D. Hypophosphatemia - CORRECT ANSWER✔✔D. Hypophosphatemia
Explanation: TLS is a situation in which a significant number of cancer cells die in a short amount
of time, releasing thier contents into the bloodstream. Hypophosphatemia is defined as a
phosphate level in the blood of an adult of less than 2.5 (mg/dL). The typical amount of serum
phosphate in children is much greater, with children have a level of 7mg/dL. Hypophosphatemia
is a fairly common laboratory condition that is frequently discovered by chance.
Question: When a patient senses a leaking in IV site during a chemotherapy infusion, what does
the nurse do first?
A. Place warning signs across the area to alert others to the spill
B. Restart the chemotherapy with a new order
C. Put on the right safety gear
D. Environmental programs should be contacted - CORRECT ANSWER✔✔A. Place a warning
signs across the area to alert others to the spill
Explanation: People who treat or come into contact with chemotherapy drugs are known to be
at risk. This suggests that the medicines are powerful enough to harm or destroy cancer cells,
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which is good news for patients. However, this means that drugs could pose a risk to those who
are exposed to them. This is why chemo drug handlers must adhere to such safety guidelines
and recommendations. If IV chemo is spilled, powder or dust from a pill or tablet, or liquid from
oral or other types of chemo is present, it may be dangerous to others.
Question: Which of the following is the leading cause of death after a cord blood transplant?
A. Infection
B. Bleeding
C. Malnutrition
D. Renal Failure - CORRECT ANSWER✔✔A. Infection
Explanation: Like bone marrow and peripheral blood, umbilical cord blood is risk source of stem
cells for transplantation. It does, however, come with a few risks. "Infection" is one of the most
serious risks that can lead to death. Infection is thought to be responsible for 35-50% of non-
relapse mortality in UCBT patients, compared to 8-22% in allogeneic HCT patients. Following
UCBT, viral infection, particularly cytomegalovirus (CMV) and human herpesvirus 6 (HHV-6),
have been linked to an increase in morbidity and death.
Question: A medical treatment that removed blood via machine and isolates white blood cells
has shown to reduce the severity of oral chronic GVHD. Identify the treatment from below?
A. Methotrexate
B. Mercaptopruine
C. ECP
D. IBD - CORRECT ANSWER✔✔C. ECP
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SUCCESS!
BMTCN TESTBANK EXAM A&B ALL COMPLETE 500
QUESTIONS AND CORRECT AND RATIONALES
SOLUTIONS JUST RELEASED THIS YEAR
Question: Which of the following drugs will most likely lead to heart failure as being used in the
conditioning regimen?
A. Busulfan
B. Cytarabine
C. Fludarabine
D. Cyclophosphamide - CORRECT ANSWER✔✔D. Cyclophosphamide
Explanation: Cardiac toxicity is the result of harmful chemicals causing damage to the heart.
Toxins (drugs) may be administered to you as part of your treatment to destroy cancer cells.
Normal cells in and around your heart can also be killed as a side effect. Patients taking a
cumulative dose of more than 150mg/kg cyclophosphamide have a 7-33% chance of developing
acute heart failure. Depending on the dosing regimen and patient population, fatal
cyclophosphamide cardiomyopathy can range from 2 to 17%.
Question: Daisy has leukemia. She will require HSCT treatment. In this situation, which of the
following is the most important thing for the nurse to consider while teaching her caregiver?
A. Request that the teaching be done by a nurse who is not caring for the patient
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B. Discuss the probability of transferring the details to someone other than the caregiver
C. Concentrate on details about the present stage of treatment
D. Keep track of the caregiver's emotional reaction - CORRECT ANSWER✔✔C. Concentrate on
details about the present stage of treatment
Explanation: A successful caregiver must have the ability to develop adequate coping strategies,
solve problems, and prioritize. To be able to offer adequate treatment for an HSCT recipient, the
caregiver must preserve his or her own quality of life -- including mental, physical, and
emotional health -- during the transplanting phase. Since the conditions of patients and their
caregivers change with each phase of treatment, it's critical to customize teaching to the
particular phase of treatment.
Question: Under utilization for certain diseases occurs due to transplant-related toxicity. For
which of the following disease is transplant-related toxicity a barrier?
A. Neuroblastoma
B. Arrhythmia
C. Acute Myeloid Leukemia
D. Sickle Cell Disease - CORRECT ANSWER✔✔D. Sickle Cell Disease
Explanation: While the clinical course of sickle cell disease (SCD) varies, many patients
experience end-organ complications that are associated with severe morbidity and mortality.
While myeloablative allogeneic HSCT (allo-HSCT) is curative, it has traditionally been reserved
for children under the age of 16. Sickle cell disease (SCD) is triggered by a single nucleotide
mutation in the -globin protein, which replaces glutamate with valine in the 6th spot. The
hemoglobin protein is more likely to polymerize when deoxygenated as a result of this
transition, resulting in sickle-shaped red cells.
2
SUCCESS!
,Page 3 of 176
Question: Identify which among the following electrolyte abnormalities, is not characterized as
an acute tumor lysis syndrome?
A. Hypocalcemia
B. Hyperkalemia
C. Hyperuricermia
D. Hypophosphatemia - CORRECT ANSWER✔✔D. Hypophosphatemia
Explanation: TLS is a situation in which a significant number of cancer cells die in a short amount
of time, releasing thier contents into the bloodstream. Hypophosphatemia is defined as a
phosphate level in the blood of an adult of less than 2.5 (mg/dL). The typical amount of serum
phosphate in children is much greater, with children have a level of 7mg/dL. Hypophosphatemia
is a fairly common laboratory condition that is frequently discovered by chance.
Question: When a patient senses a leaking in IV site during a chemotherapy infusion, what does
the nurse do first?
A. Place warning signs across the area to alert others to the spill
B. Restart the chemotherapy with a new order
C. Put on the right safety gear
D. Environmental programs should be contacted - CORRECT ANSWER✔✔A. Place a warning
signs across the area to alert others to the spill
Explanation: People who treat or come into contact with chemotherapy drugs are known to be
at risk. This suggests that the medicines are powerful enough to harm or destroy cancer cells,
3
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, Page 4 of 176
which is good news for patients. However, this means that drugs could pose a risk to those who
are exposed to them. This is why chemo drug handlers must adhere to such safety guidelines
and recommendations. If IV chemo is spilled, powder or dust from a pill or tablet, or liquid from
oral or other types of chemo is present, it may be dangerous to others.
Question: Which of the following is the leading cause of death after a cord blood transplant?
A. Infection
B. Bleeding
C. Malnutrition
D. Renal Failure - CORRECT ANSWER✔✔A. Infection
Explanation: Like bone marrow and peripheral blood, umbilical cord blood is risk source of stem
cells for transplantation. It does, however, come with a few risks. "Infection" is one of the most
serious risks that can lead to death. Infection is thought to be responsible for 35-50% of non-
relapse mortality in UCBT patients, compared to 8-22% in allogeneic HCT patients. Following
UCBT, viral infection, particularly cytomegalovirus (CMV) and human herpesvirus 6 (HHV-6),
have been linked to an increase in morbidity and death.
Question: A medical treatment that removed blood via machine and isolates white blood cells
has shown to reduce the severity of oral chronic GVHD. Identify the treatment from below?
A. Methotrexate
B. Mercaptopruine
C. ECP
D. IBD - CORRECT ANSWER✔✔C. ECP
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