Test Bank for Principles of Epidemiology
for Advanced Nursing Practice, 1st Edition
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
4. Are most common in collagen tissues - ANSWERS3. Increase the length of time a drug is available
and active
Azithromycin dosing requires that the first day's dosage be twice those of the other
4 days of the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues - ANSWERS1. Rapidly achieves drug
levels in the therapeutic range
The ailment that generates the greatest over-the-counter annual drug sales is:
1. Constipation
,2. Cough and colds
3. Heartburn
4. Acute and chronic pain - ANSWERS2. Cough and colds
The Combat Methamphetamine Epidemic Act, which is part of the 2006 U.S. Patriot Act:
1. Requires all providers to screen their patients for methamphetamine use
2. Restricts the prescribing of amphetamines to U.S. citizens
3. Requires a prescription be written for all methamphetamine precursors in all states
4. Restricts the sales of drugs that contain methamphetamine precursors, including a daily and 30-
day limit on sales - ANSWERS4. Restricts the sales of drugs that contain methamphetamine
precursors, including a daily and 30-day limit on sales
When prescribing a tetracycline or quinolone antibiotic it is critical to instruct the
patient:
1. Not to take their regularly prescribed medications while on these antibiotics
2. Regarding the need for lots of acidic foods and juices, such as orange juice, to enhance absorption
3. Not to take antacids while on these medications, as the antacid decreases absorption
4. That there are no drug interactions with these antibiotics - ANSWERS3. Not to take antacids while
on these medications, as the antacid decreases absorption
Factors that place a patient at risk of developing an antimicrobial-resistant organism include:
,1. Age over 50 years
2. School attendance
3. Travel within the U.S.
4. Inappropriate use of antimicrobials - ANSWERS4. Inappropriate use of antimicrobials
Infants and young children are at higher risk of developing antibiotic-resistant infections due to:
1. Developmental differences in pharmacokinetics of the antibiotics in children
2. The fact that children this age are more likely to be in daycare and exposed to pathogens from
other children
3. Parents of young children insisting on preventive antibiotics so they don't miss work when their
child is sick
4. Immunosuppression from the multiple vaccines they receive in the first 2 years of life -
ANSWERS2. The fact that children this age are more likely to be in daycare and exposed to
pathogens from other children
Providers should use an antibiogram when prescribing. An antibiogram is:
1. The other name for the Centers for Disease Control guidelines for prescribing antibiotics
2. An algorithm used for prescribing antibiotics for certain infections
3. The reference also known as the Pink Book, published by the Centers for Disease Control
4. A chart of the local resistance patterns to antibiotics developed by laboratories - ANSWERS4. A
chart of the local resistance patterns to antibiotics developed by laboratories
, There is often cross-sensitivity and cross-resistance between penicillins and cephalosporins because:
1. Renal excretion is similar in both classes of drugs.
2. When these drug classes are metabolized in the liver they both produce resistant enzymes.
3. Both drug classes contain a beta-lactam ring that is vulnerable to beta-lactamase-producing
organisms.
4. There is not an issue with cross-resistance between the penicillins and cephalosporins. -
ANSWERS3. Both drug classes contain a beta-lactam ring that is vulnerable to beta-lactamase-
producing organisms.
Jonathan has been diagnosed with strep throat and needs a prescription for an antibiotic. He says
the last time he had penicillin he developed a red, blotchy rash. An appropriate antibiotic to
prescribe would be:
1. Penicillin VK, because his rash does not sound like a serious rash
2. Amoxicillin
3. Cefadroxil (Duricef)
4. Azithromycin - ANSWERS4. Azithromycin
Sarah is a 25-year-old female who is 8 weeks pregnant and has a urinary tract infection. What would
be the appropriate antibiotic to prescribe for her?
1. Ciprofloxacin (Cipro)
2. Amoxicillin (Trimox)
for Advanced Nursing Practice, 1st Edition
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
4. Are most common in collagen tissues - ANSWERS3. Increase the length of time a drug is available
and active
Azithromycin dosing requires that the first day's dosage be twice those of the other
4 days of the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues - ANSWERS1. Rapidly achieves drug
levels in the therapeutic range
The ailment that generates the greatest over-the-counter annual drug sales is:
1. Constipation
,2. Cough and colds
3. Heartburn
4. Acute and chronic pain - ANSWERS2. Cough and colds
The Combat Methamphetamine Epidemic Act, which is part of the 2006 U.S. Patriot Act:
1. Requires all providers to screen their patients for methamphetamine use
2. Restricts the prescribing of amphetamines to U.S. citizens
3. Requires a prescription be written for all methamphetamine precursors in all states
4. Restricts the sales of drugs that contain methamphetamine precursors, including a daily and 30-
day limit on sales - ANSWERS4. Restricts the sales of drugs that contain methamphetamine
precursors, including a daily and 30-day limit on sales
When prescribing a tetracycline or quinolone antibiotic it is critical to instruct the
patient:
1. Not to take their regularly prescribed medications while on these antibiotics
2. Regarding the need for lots of acidic foods and juices, such as orange juice, to enhance absorption
3. Not to take antacids while on these medications, as the antacid decreases absorption
4. That there are no drug interactions with these antibiotics - ANSWERS3. Not to take antacids while
on these medications, as the antacid decreases absorption
Factors that place a patient at risk of developing an antimicrobial-resistant organism include:
,1. Age over 50 years
2. School attendance
3. Travel within the U.S.
4. Inappropriate use of antimicrobials - ANSWERS4. Inappropriate use of antimicrobials
Infants and young children are at higher risk of developing antibiotic-resistant infections due to:
1. Developmental differences in pharmacokinetics of the antibiotics in children
2. The fact that children this age are more likely to be in daycare and exposed to pathogens from
other children
3. Parents of young children insisting on preventive antibiotics so they don't miss work when their
child is sick
4. Immunosuppression from the multiple vaccines they receive in the first 2 years of life -
ANSWERS2. The fact that children this age are more likely to be in daycare and exposed to
pathogens from other children
Providers should use an antibiogram when prescribing. An antibiogram is:
1. The other name for the Centers for Disease Control guidelines for prescribing antibiotics
2. An algorithm used for prescribing antibiotics for certain infections
3. The reference also known as the Pink Book, published by the Centers for Disease Control
4. A chart of the local resistance patterns to antibiotics developed by laboratories - ANSWERS4. A
chart of the local resistance patterns to antibiotics developed by laboratories
, There is often cross-sensitivity and cross-resistance between penicillins and cephalosporins because:
1. Renal excretion is similar in both classes of drugs.
2. When these drug classes are metabolized in the liver they both produce resistant enzymes.
3. Both drug classes contain a beta-lactam ring that is vulnerable to beta-lactamase-producing
organisms.
4. There is not an issue with cross-resistance between the penicillins and cephalosporins. -
ANSWERS3. Both drug classes contain a beta-lactam ring that is vulnerable to beta-lactamase-
producing organisms.
Jonathan has been diagnosed with strep throat and needs a prescription for an antibiotic. He says
the last time he had penicillin he developed a red, blotchy rash. An appropriate antibiotic to
prescribe would be:
1. Penicillin VK, because his rash does not sound like a serious rash
2. Amoxicillin
3. Cefadroxil (Duricef)
4. Azithromycin - ANSWERS4. Azithromycin
Sarah is a 25-year-old female who is 8 weeks pregnant and has a urinary tract infection. What would
be the appropriate antibiotic to prescribe for her?
1. Ciprofloxacin (Cipro)
2. Amoxicillin (Trimox)
