HESI ADULT HEALTH 2 EXAM (2025/2026 EDITION)
Actual Exam Questions with Verified Answers | Comprehensive Medical-Surgical Assessment |
NCLEX®-Ready
Overview
This 2025/2026 validated resource contains actual HESI Adult Health 2 exam
questions with 100% verified answers, directly aligned with the current Evolve assessment
blueprint. Essential for nursing students preparing for medical-surgical course finals, exit
exams, and NCLEX® readiness.
Key Features
✓ 60-Question Exam matching official test format
✓ Detailed clinical rationales with nursing interventions
✓ Priority decision-making for complex patient scenarios
✓ Updated 2025/2026 clinical guidelines and protocols
✓ Dosage calculation problems with step-by-step solutions
Content Domains
* Cardiovascular Disorders (12 Qs)
* Respiratory Conditions (10 Qs)
* Neurological Emergencies (10 Qs)
* Endocrine/Metabolic (8 Qs)
* Renal/Gastrointestinal (8 Qs)
* Complex Multi-System (12 Qs)
Answer Format
Correct answers in bold green with:
* Pathophysiology explanations
* Nursing priority actions
* Medication administration guidelines
* Assessment finding correlations
Critical Updates 2025/2026
New sepsis management protocols
Revised heart failure guidelines
Updated diabetes management standards
Modified stroke intervention timelines
Cardiovascular Disorders (Questions 1–12)
,1. A 68-year-old male with heart failure (HFrEF) presents with dyspnea, 3+ pitting
edema, and JVD. Which medication should the nurse anticipate administering
first?
A) Furosemide 40 mg IV
B) Carvedilol 6.25 mg PO
C) Digoxin 0.125 mg PO
D) Lisinopril 5 mg PO
A) Furosemide 40 mg IV
Pathophysiology: Volume overload → pulmonary congestion.
Nursing Priority: Reduce preload and relieve dyspnea.
Medication Guideline: Loop diuretic first-line for acute decompensation (2025 AHA).
Assessment Correlation: Crackles, weight gain >2 kg.
2. A patient post-MI develops ventricular tachycardia. The nurse prepares to
administer which drug?
A) Amiodarone 150 mg IV bolus
B) Metoprolol 5 mg IV
C) Lidocaine 1 mg/kg IV
D) Adenosine 6 mg IV
A) Amiodarone 150 mg IV bolus
Pathophysiology: Re-entrant arrhythmia in ischemic tissue.
Nursing Priority: Stabilize rhythm (ACLS 2025).
Medication Guideline: Amiodarone first-line for VT with pulse.
Assessment Correlation: Wide QRS, HR >150.
3. A patient on warfarin has INR 5.8 without bleeding. What is the priority action?
A) Administer vitamin K 2.5 mg PO
B) Hold warfarin and monitor
C) Give FFP
D) Continue current dose
B) Hold warfarin and monitor
Pathophysiology: Supratherapeutic anticoagulation.
Nursing Priority: Prevent bleeding (2025 ACC).
Medication Guideline: INR 5–9, no bleeding → hold 1–2 doses.
Assessment Correlation: Check for bruising, gum bleeding.
4. A patient with atrial fibrillation is prescribed apixaban. Which lab is most
important to monitor?
A) INR
B) aPTT
C) Serum creatinine
D) Platelet count
C) Serum creatinine
Pathophysiology: Renal clearance (80%).
Nursing Priority: Adjust dose in CKD.
, Medication Guideline: Reduce dose if CrCl <30 mL/min.
Assessment Correlation: eGFR <60 → risk of accumulation.
5. A patient with chest pain has troponin 0.8 ng/mL. What is the interpretation?
A) Normal
B) NSTEMI
C) Unstable angina
D) Pericarditis
B) NSTEMI
Pathophysiology: Myocardial necrosis.
Nursing Priority: Activate cath lab.
Medication Guideline: MONA + heparin.
Assessment Correlation: ST depression, T-wave inversion.
6. A patient on dobutamine develops HR 128 bpm. What is the next action?
A) Increase infusion
B) Decrease rate or hold
C) Administer digoxin
D) No change
B) Decrease rate or hold
Pathophysiology: β₁ stimulation → tachycardia.
Nursing Priority: Prevent ischemia.
Medication Guideline: Target HR <110.
Assessment Correlation: PVCs, chest pain.
7. A patient with PAD has ankle-brachial index (ABI) of 0.6. What is the
classification?
A) Normal
B) Mild
C) Moderate
D) Severe
D) Severe
Pathophysiology: Arterial occlusion.
Nursing Priority: Refer for revascularization.
Medication Guideline: Cilostazol, statins.
Assessment Correlation: Claudication <1 block.
8. Dosage Calculation: Order: Nitroglycerin drip at 5 mcg/min. Available: 50 mg in
250 mL D5W. Infuse at ___ mL/hr?
A) 1.5 mL/hr
B) 3 mL/hr
C) 4.5 mL/hr
D) 6 mL/hr
B) 3 mL/hr
Step-by-Step:
1. 50 mg = 50,000 mcg in 250 mL → 200 mcg/mL
Actual Exam Questions with Verified Answers | Comprehensive Medical-Surgical Assessment |
NCLEX®-Ready
Overview
This 2025/2026 validated resource contains actual HESI Adult Health 2 exam
questions with 100% verified answers, directly aligned with the current Evolve assessment
blueprint. Essential for nursing students preparing for medical-surgical course finals, exit
exams, and NCLEX® readiness.
Key Features
✓ 60-Question Exam matching official test format
✓ Detailed clinical rationales with nursing interventions
✓ Priority decision-making for complex patient scenarios
✓ Updated 2025/2026 clinical guidelines and protocols
✓ Dosage calculation problems with step-by-step solutions
Content Domains
* Cardiovascular Disorders (12 Qs)
* Respiratory Conditions (10 Qs)
* Neurological Emergencies (10 Qs)
* Endocrine/Metabolic (8 Qs)
* Renal/Gastrointestinal (8 Qs)
* Complex Multi-System (12 Qs)
Answer Format
Correct answers in bold green with:
* Pathophysiology explanations
* Nursing priority actions
* Medication administration guidelines
* Assessment finding correlations
Critical Updates 2025/2026
New sepsis management protocols
Revised heart failure guidelines
Updated diabetes management standards
Modified stroke intervention timelines
Cardiovascular Disorders (Questions 1–12)
,1. A 68-year-old male with heart failure (HFrEF) presents with dyspnea, 3+ pitting
edema, and JVD. Which medication should the nurse anticipate administering
first?
A) Furosemide 40 mg IV
B) Carvedilol 6.25 mg PO
C) Digoxin 0.125 mg PO
D) Lisinopril 5 mg PO
A) Furosemide 40 mg IV
Pathophysiology: Volume overload → pulmonary congestion.
Nursing Priority: Reduce preload and relieve dyspnea.
Medication Guideline: Loop diuretic first-line for acute decompensation (2025 AHA).
Assessment Correlation: Crackles, weight gain >2 kg.
2. A patient post-MI develops ventricular tachycardia. The nurse prepares to
administer which drug?
A) Amiodarone 150 mg IV bolus
B) Metoprolol 5 mg IV
C) Lidocaine 1 mg/kg IV
D) Adenosine 6 mg IV
A) Amiodarone 150 mg IV bolus
Pathophysiology: Re-entrant arrhythmia in ischemic tissue.
Nursing Priority: Stabilize rhythm (ACLS 2025).
Medication Guideline: Amiodarone first-line for VT with pulse.
Assessment Correlation: Wide QRS, HR >150.
3. A patient on warfarin has INR 5.8 without bleeding. What is the priority action?
A) Administer vitamin K 2.5 mg PO
B) Hold warfarin and monitor
C) Give FFP
D) Continue current dose
B) Hold warfarin and monitor
Pathophysiology: Supratherapeutic anticoagulation.
Nursing Priority: Prevent bleeding (2025 ACC).
Medication Guideline: INR 5–9, no bleeding → hold 1–2 doses.
Assessment Correlation: Check for bruising, gum bleeding.
4. A patient with atrial fibrillation is prescribed apixaban. Which lab is most
important to monitor?
A) INR
B) aPTT
C) Serum creatinine
D) Platelet count
C) Serum creatinine
Pathophysiology: Renal clearance (80%).
Nursing Priority: Adjust dose in CKD.
, Medication Guideline: Reduce dose if CrCl <30 mL/min.
Assessment Correlation: eGFR <60 → risk of accumulation.
5. A patient with chest pain has troponin 0.8 ng/mL. What is the interpretation?
A) Normal
B) NSTEMI
C) Unstable angina
D) Pericarditis
B) NSTEMI
Pathophysiology: Myocardial necrosis.
Nursing Priority: Activate cath lab.
Medication Guideline: MONA + heparin.
Assessment Correlation: ST depression, T-wave inversion.
6. A patient on dobutamine develops HR 128 bpm. What is the next action?
A) Increase infusion
B) Decrease rate or hold
C) Administer digoxin
D) No change
B) Decrease rate or hold
Pathophysiology: β₁ stimulation → tachycardia.
Nursing Priority: Prevent ischemia.
Medication Guideline: Target HR <110.
Assessment Correlation: PVCs, chest pain.
7. A patient with PAD has ankle-brachial index (ABI) of 0.6. What is the
classification?
A) Normal
B) Mild
C) Moderate
D) Severe
D) Severe
Pathophysiology: Arterial occlusion.
Nursing Priority: Refer for revascularization.
Medication Guideline: Cilostazol, statins.
Assessment Correlation: Claudication <1 block.
8. Dosage Calculation: Order: Nitroglycerin drip at 5 mcg/min. Available: 50 mg in
250 mL D5W. Infuse at ___ mL/hr?
A) 1.5 mL/hr
B) 3 mL/hr
C) 4.5 mL/hr
D) 6 mL/hr
B) 3 mL/hr
Step-by-Step:
1. 50 mg = 50,000 mcg in 250 mL → 200 mcg/mL
