QUESTIONS WITH CORRECT DETAILED
ANSWERS ALREADY GRADED A+
◉Lead absorption is enhanced if the diet is poor in iron or calcium. True
or false? Ans: True
◉Lead is stored in bone tissues for how many years? Ans: over 30
years.
◉What is the key molecular mechanism of lead toxicity? Ans: Lead
binds to enzymes that have functional sulfhydryl groups, leaving them
nonfunctional and further contributing to impairment in oxidative
balance.
◉How does lead affect male fertility? Ans: Decrease libido
Fertility problems
Damage to sperm
Decreased size of testis
Increase spouses chance of miscarriage, premature birth, and birth
defects
,◉How many years can mercury last in the ocean? Ans: 80,000 years
◉Asian countries contribute about what % of global air emissions? Ans:
50%
◉What is the largest and most frequent source of mercury in the air?
Ans: emissions from electric utility coal-fired plants.
◉Which state in the US has the highest mercury pollution in the air?
Ans: Texas
◉Mention two high mercury fish and low mercury fish Ans: High: tuna
and catfish
Low: trout and sardines
◉What are the mercury toxicity symptoms in fetus/infants? Ans:
Mental retardation, seizures, blindness and deafness, speech, swallow,
and sucking problem
◉Describe Minamata disease? Ans: Methyl mercury was released into
the sea around this area in Japan. The toxin bioaccumulates in fish and
when eaten by the local people, it causes the largest case of mercury
poisoning. Causing death and many disabled people
, ◉Young's syndrome & Pink Disease are associated with which toxicity?
Ans: Mercury
◉50-75% of total body Cadmium is found in which tissue? Ans: liver
and kidney
◉Half life of Cadmium in the human body? Ans: 20-30 years
◉How does Cd affect the metabolism of other essential metals? Ans:
Interacts with essential nutrients
Competes with gastrointestinal absorption of zinc
Inhibits zinc enzymes
Decreases copper in liver and plasma
Binds to ferritin, decreases hemoglobin
Deposits in bones
Increases oxidative stress
◉How does Cadmium affects steroidogenesis? Ans: decreased
(3bHSD) and (17b-HSD)- the key enzymes for testosterone biosynthesis.
◉Briefly describe "itai-itai" disease. Ans: Outflow from a lead
processing plant washed over adjacent rice paddies for many years. Rice
accumulated high levels of Cd therefore it caused renal failure, anemia,
and severe muscle pain