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Why is Rouleaux formation associated with Multiple Myeloma and Waldenstrom's
macroglobulinemia?
A. abnormal proteins secreted from megakaryocytes coat red blood cells causing them
to appear stacked on the peripheral blood smear
B. abnormal proteins produced from T lymphocytes coat red blood cells causing them
to appear stacked on the peripheral blood smear
C. abnormal proteins produced from segmented neutrophils coat red blood cells
causing them to appear stacked on the peripheral blood smear
D. abnormal proteins produced from myeloma cells coat red blood cells causing them
to appear stacked on the peripheral blood smear -CORRECT ANSWER abnormal
proteins produced from myeloma cells coat red blood cells causing them to appear
stacked on the peripheral blood smear
A "dry tap" bone marrow aspiration may be seen with what chronic myeloid proliferative
disease?
A. Essential Thrombocythemia
B. Polycythemia Vera
C. Primary Myelofibrosis
D. Chronic Myeloid Leukemia -CORRECT ANSWER Primary Myelofibrosis
What clinical feature is more often associated with essential thrombocythemia than with
the other chronic myeloproliferative disorders?
A. bleeding and thrombosis
B. infections
C. splenomegaly
D. fatigue -CORRECT ANSWER bleeding and thrombosis
How is Waldenstrom's macroglobulinemia described?
A. Abnormal IgA immunoglobulin produced from pathological plasma cells
B. Abnormal IgD immunoglobulin produced from pathological plasma cells
C. Abnormal IgG immunoglobulin produced from pathological plasma cells
D. abnormal IgM Immunoglobulin produced from pathological plasma cells -CORRECT
ANSWER abnormal IgM Immunoglobulin produced from pathological plasma cells
, The presence of this cell is definitive for Hodgkins Lymphoma:
A. Flame cell
B. Reed-Sternberg cell
C. dendritic cell
D. Plasma cell -CORRECT ANSWER Reed-Sternberg cell
Which of the following is a B cell marker?
A. CD4
B. CD20
C. CD8
D. CD2 -CORRECT ANSWER CD20
What is the most common chromosomal abnormality in Polycythemia Vera (PV)?
A. BCR-ABL
B. PML-RARA
C. TET2
D. JAK2V617F -CORRECT ANSWER JAK2V617F
This finding can be present in both Multiple Myeloma and Waldenstrom's
macroglobulinemia
A. High MCV
B. Bence- Jones proteinuria
C. decreased serum iron
D. Glycosuria -CORRECT ANSWER Bence- Jones proteinuria
Which of the following is an expected finding in polycythemia vera?
A. normal white cell count
B. anemia
C. increased RBC mass
D. low leukocyte alkaline phosphatase -CORRECT ANSWER increased RBC mass
Which of the following is seen in Burkitt's Lymphoma?
A. granules stain reddish-orange
B. lymphocyte cells have hairy cytoplasmic projections
C. lymphocytic cells have vacuoles in basophilic cytoplasm
D. lymphocytic cells have Auer rods -CORRECT ANSWER lymphocytic cells have
vacuoles in basophilic cytoplasm