Test Bank for Clayton’s Basic Pharmacology for Nurses 20th Edition by Michelle J. Willihnganz & Samuel L. Gurevitz – Complete Guide (ISBN 9780443126994)

TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
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Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
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Clayton’sBasicPharmacologyforNurses,19thEdition
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MULTIPLECHOICE 8f




1. Whichnameidentifies adruglisted bythe US Food and 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f




Drug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark

ANS: C 8 f




The official name is the name under which a drug is listed by the
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FDA. The brand name, or trademark, is the name given to a drug
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by its manufacturer. The nonproprietary, or generic, name is
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provided by the United States Adopted Names Council.
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DIF: CognitiveLevel:Knowledge REF: p. 9 8f 8f 8 f 8f




OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care 8f 8f 8f 8f 8f 8f 8f 8f




Environment TOP: Nursing Process Step: Assessment
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Patient Education
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2. Whichsourcecontainsinformation specificto nutritional supplements?
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a. USPDictionary of USAN &International Drug Names 8f 8f 8f 8 f 8f 8f 8f




b. NaturalMedicinesComprehensiveDatabase 8f 8f 8f




c. UnitedStatesPharmacopoeia/NationalFormulary(USPNF) 8f 8f 8f 8f 8f




d. DrugInteractionFacts 8f 8f




ANS: C 8 f




UnitedStatesPharmacopoeia/NationalFormularycontainsinformationspecifictonutritional
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supplements. USP Dictionary of USAN &International Drug Names is a compilation of drug
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names, pronunciation guide, and possible future FDA approved drugs; it does not include
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nutritional supplements. Natural Medicines Comprehensive Database contains
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evidence-basedinformationonherbalmedicines andherbalcombinationproducts;itdoesnot 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f




include information specific to nutritional supplements. Drug Interaction Facts contains
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comprehensive information on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 8f 8f 8 f 8f 8f




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcessStep: Assessment
8 CON: Nutrition|Patient Education
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3. Whichdrugreference contains drugmonographs that describe all drugs ina therapeutic class?
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a. DrugFactsandComparisons 8f 8f 8f




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition 8f 8f 8f 8f 8f 8f 8f 8f 8f

,TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
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b. DrugInteractionFacts 8f 8f




c. Handbookon Injectable Drugs 8f 8f 8f




d. Martindale—TheCompleteDrugReference 8f 8f 8f




ANS: A 8 f




Drug Facts and Comparisons contains drug monographs that describe all drugs in a
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therapeuticclass.Monographsareformattedastablestoallowcomparison ofsimilar
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products, brand names, manufacturers, cost indices, and available dosage forms Online
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version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 8f 8f 8 f 8f 8f 8f




OBJ: 3 NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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TOP: NursingProcessStep: Assessment CON: Safety|Patient Education|Clinical Judgment
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4. Whichdrugreference contains monographs about virtuallyeverysingle-entitydrugavailable in
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the United States and describes therapeutic uses of drugs, including approved and unapproved
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uses?
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a. Martindale:TheCompleteDrugReference 8f 8f 8f 8f




b. AHFSDrugInformation 8f 8f




c. DrugReference 8f




d. DrugFactsandComparisons 8f 8f 8f




ANS: B 8 f




AHFS Drug Information contains monographs about virtually every single-entity drug available
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intheUnitedStatesanddescribes therapeuticusesofdrugs, includingapproved and unapproved
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uses.
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DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 8f 8f 8 f 8f 8f 8f




OBJ: 3 NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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TOP: NursingProcess Step: Planning CON: Safety|Patient Education|Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a standard,
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comprehensive, up-to-datelookupanddownloadableresourceaboutmedicines?
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a. AmericanDrugIndex 8f 8f




b. AmericanHospitalFormulary 8f 8f




c. DailyMed
d. DrugReference 8f




ANS: C 8 f




DailyMed makes available tohealthcareproviders and thepublic astandard,comprehensive, up- 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f




to-datelook upanddownloadableresourceabout medicines. TheAmericanDrugIndexis not
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appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
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The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 8f 8f 8 f 8f 8f 8f 8f OBJ:3 8f




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcessStep: Implementation
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CON: Safety|PatientEducation|ClinicalJudgment
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6. Whichlegislation authorizestheFDAto determinethesafetyof adrugbeforeits marketing?
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a. FederalFood,Drug,and CosmeticAct(1938) 8f 8f 8f 8f 8f 8f




b. DurhamHumphreyAmendment (1952) 8f 8f 8f




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition 8f 8f 8f 8f 8f 8f 8f 8f 8f 8 f

,TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
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c. ControlledSubstancesAct(1970) 8f 8f 8f




d. KefauverHarrisDrugAmendment(1962) 8f 8f 8f 8f




ANS: A 8 f




The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of
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all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
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drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
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safely without medical supervision and restricts their sale to prescription by a licensedpractitioner.
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The ControlledSubstancesActaddressesonlycontrolledsubstances and their categorization. The
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Kefauver Harris Drug Amendment ensures drug efficacyand greater drug safety. Drug
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manufacturers are required to prove to the FDA the effectiveness of their products before
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marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 5Table l.3 8f 8f 8 f 8f 8f 8f




OBJ: 8 f 5 NAT: NCLEX Client NeedsCategory: Physiological Integrity 8f 8f 8f 8f 8f 8f




TOP:
8f 8 Nursing Process Step: Assessment
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CON: 8 Safety|Patient Education|Evidence |Health Care Law
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7. Whichclassification doesmeperidine(Demerol)fall under? 8f 8f 8f 8f 8f 8f




a. I
b. II
c. III
d. IV
ANS: B 8 f




Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f




psychological and physical dependence. Schedule Idrugs havehigh potentialforabuse and no
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recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low to
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moderate physical dependence or high psychological dependence. Schedule IV drugs have low
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potential for abuse. Use may lead to limited physical or psychological dependence.
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DIF: Cognitive Level: Knowledge REF: p. 10 OBJ:2 8f 8f 8 f 8f 8f




NAT: NCLEXClient NeedsCategory: Safe,EffectiveCareEnvironment
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TOP: NursingProcessStep: Assessment
8 CON: Patient Education|Addiction|Pain
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8. Whichaction wouldtheFDAtaketo expeditedrugdevelopment and approval foran outbreak of
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smallpox?
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a. Listsmallpox asahealth orphandisease. 8f 8f 8f 8f 8f 8f




b. Omitthepreclinical researchphase. 8f 8f 8f 8f




c. Extendtheclinicalresearchphase. 8f 8f 8f 8f




d. Fasttracktheinvestigationaldrug. 8f 8f 8f 8f




ANS: D 8 f




Once the Investigational New Drug Application has been approved, the drug can receive highest
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priority within the agency, which is called fast tracking. A smallpox outbreak would become a
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priority concern in the world. Orphan diseases are not researched in a priority manner. Preclinical
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research is not omitted. Extending any phase of the research would mean alongertimeto develop a
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vaccine.The FDAmust ensurethatall phasesof thepreclinical and clinical research phase have been
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completed in a safe manner.
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DIF: Cognitive Level: Knowledge 8f 8f REF: p. 7 8 f 8 f 8f OBJ: 8 f 5




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition 8f 8f 8f 8f 8f 8f 8f 8f 8f 8 f

, TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
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NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
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TOP: Nursing Process Step: Assessment
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CON: HealthCareLaw|Health CarePolicy|Infection|CareCoordination
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9. Whichstatement is trueabout over-the-counter(OTC) drugs?8f 8f 8f 8f 8f 8f 8f




a. Theyare not listed in theUSPNF. 8f 8f 8f 8f 8f 8f 8f




b. Aprescription froma healthcareprovideris needed.
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c. Theyaresold without aprescription. 8f 8f 8f 8f 8f




d. Theyare known onlybytheir brand names. 8f 8f 8f 8f 8f 8f 8f




ANS: C 8 f




OTC medications do not require a prescription. A variety of names, both generic and trade, canbe
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used forindividualdrugs sold OTC.OTC drugs arelisted inthe USPNF. Prescription drugs require
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an order by a health professional who is licensed to prescribe, such as a physician, nurse
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practitioner, physician assistant, or dentist.
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DIF: Cognitive Level: Comprehension REF: p. 2 OBJ:2 8f 8f 8 f 8f 8f




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcess Step: Planning 8 CON: PatientEducation
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10. Whichisthemost authoritativereference formedicationsthatareinjected?
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a. Martindale:TheComplete 8f 8f




b. Handbookon Injectable Drugs 8f 8f 8f




c. DailyMed
d. HandbookofNonprescriptionDrugs 8f 8f 8f




ANS: B 8 f




The Handbook on Injectable Drugs is the most comprehensive reference available on the topicof
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compatibilityofinjectabledrugs. It isacollection ofmonographs formorethan300 injectable drugs
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that are listed alphabetically by generic name.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 8f 8f 8 f 8f 8f




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcessStep: Assessment8 CON: ClinicalJudgment |Safety
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11. Whichstatement istrueabout Lomotil? 8f 8f 8f 8f 8f




a. Abusepotential forthis drugis low. 8f 8f 8f 8f 8f 8f




b. Psychologicaldependencyislikely. 8f 8f 8f




c. Thereis ahigh potential forabuse. 8f 8f 8f 8f 8f 8f




d. This drugis not acontrolled substance. 8f 8f 8f 8f 8f 8f




ANS: A 8 f




Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f 8f




dependenceliabilitycomparedwith drugs inSchedule IV. Because abusepotential islowwith a
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Schedule Vdrug, a prescription maynot be required. Psychological dependencyis not likely with a
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Schedule V drug. Schedule V drugs are classified as controlled substances.
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DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ:2 8f 8f 8 f 8f 8f 8f 8f




NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: NursingProcessStep: Assessment8 CON: ClinicalJudgment |Safety|PatientEducation
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