MN553 Pharmacology Unit 2 Quiz
2025/2026 Exam Questions and Answers
| 100% Solved
What properties affect the distribution of drugs - 🧠 ANSWER ✔✔drug size,
charge, chemical structure, pH, molecular size, lipid or water solubility
first pass metabolism - 🧠 ANSWER ✔✔metabolism by the liver following
oral administration
Phase 1 reactions - 🧠 ANSWER ✔✔Oxidation, reduction, hydrolysis or non-
synthetic reactions that prepare the drug for further metabolism - to make
the drug more water soluble
Phase II reactions - 🧠 ANSWER ✔✔synthetic or conjugation reactions,
something is added to drug to make it more water soluble and more easily
excreted by the kidneys
CYP P450 - 🧠 ANSWER ✔✔Liver *enzyme* that detoxifies substances,
, Makes them easier to be excreted.
single nucleotide polymorphism (SNP) - 🧠 ANSWER ✔✔minor mutations
that can result in metabolic activity changes, including increased and
decreased drug responses
primary organ of excretion for drugs - 🧠 ANSWER ✔✔kidney
blood flow differences in infants - 🧠 ANSWER ✔✔increased blood flow to
muscles 1-6 mo EXCEPT during illness, can cause slower or rapid
perfusion
Pediatric GI function - 🧠 ANSWER ✔✔pH increases gradually- reaches
adult levels @ 20-30 months preemies are even slower
Diarrhea and kids - 🧠 ANSWER ✔✔kids with diarrhea have poor absorption
of oral drugs
Pediatric skin absorption - 🧠 ANSWER ✔✔Kids have thinner stratum
corneum so topical medications are absorbed more readily: increased risk
of toxicity
2025/2026 Exam Questions and Answers
| 100% Solved
What properties affect the distribution of drugs - 🧠 ANSWER ✔✔drug size,
charge, chemical structure, pH, molecular size, lipid or water solubility
first pass metabolism - 🧠 ANSWER ✔✔metabolism by the liver following
oral administration
Phase 1 reactions - 🧠 ANSWER ✔✔Oxidation, reduction, hydrolysis or non-
synthetic reactions that prepare the drug for further metabolism - to make
the drug more water soluble
Phase II reactions - 🧠 ANSWER ✔✔synthetic or conjugation reactions,
something is added to drug to make it more water soluble and more easily
excreted by the kidneys
CYP P450 - 🧠 ANSWER ✔✔Liver *enzyme* that detoxifies substances,
, Makes them easier to be excreted.
single nucleotide polymorphism (SNP) - 🧠 ANSWER ✔✔minor mutations
that can result in metabolic activity changes, including increased and
decreased drug responses
primary organ of excretion for drugs - 🧠 ANSWER ✔✔kidney
blood flow differences in infants - 🧠 ANSWER ✔✔increased blood flow to
muscles 1-6 mo EXCEPT during illness, can cause slower or rapid
perfusion
Pediatric GI function - 🧠 ANSWER ✔✔pH increases gradually- reaches
adult levels @ 20-30 months preemies are even slower
Diarrhea and kids - 🧠 ANSWER ✔✔kids with diarrhea have poor absorption
of oral drugs
Pediatric skin absorption - 🧠 ANSWER ✔✔Kids have thinner stratum
corneum so topical medications are absorbed more readily: increased risk
of toxicity
