NURS 2346 Alterations in Immunity for the
Pediatric Patient ACTUAL QUESTIONS
AND CORRECT ANSWERS
How do newborns receive passive immunity? - CORRECT ANSWERS placenta and
breastfeeding. They receive maternal antibodies
Young children tend to have larger what compared to adults? - CORRECT
ANSWERS lymph nodes, thymus, and tonsils
Difference between adaptive and innate immunity - CORRECT ANSWERS Innate acts
right away to protect body from threat. No memory of threat so will respond same in future. (use
macrophage)
Adaptive takes longer to react but more precise. Will remember the threat and respond faster and
stronger next time. (use B and T cells)
What labs will you draw if you want to know the specific count of WBC? - CORRECT
ANSWERS CBC with differential
what is passive immunity? - CORRECT ANSWERS Antibodies that are received from
external source such as (IVIG) intravenous immunoglobulin administration and placenta or
breastmilk
What is humoral immunity? Is it able to cross the placenta? If so, in what form? - CORRECT
ANSWERS B cell lymphocytes that secrete antibodies that binds and recognize antigens.
When binding together, it will recognize the foreign cell and neutralize it. It can cross the
placenta as IgG.
, What is cellular immunity? Can it cross placenta? - CORRECT ANSWERS T-cell
lymphocytes attacks infected or foreign cells. Does not recognize antigens or cross placenta.
What is SCID? - CORRECT ANSWERS severe combined immunodeficiency, an
autosomal recessive disorder where the baby is born with no T or B cell protection
What are common assessment findings of SCID? - CORRECT ANSWERS - Severe or
recurrent infections
- inability to thrive (poor growth or weight gain due to repeated infections and nutrient
absorption issues)
- diarrhea and vomiting (lead to dehydration and malnutrition)
How is SCID treated - CORRECT ANSWERS - bone marrow transplant
- IVIG infusions,
-Subq adenosine deaminase enzyme replacement
- long term antibiotic therapy, - gene therapy developments
How does a bone marrow transplant help with SCID? - CORRECT ANSWERS Stem cells
from a healthy donor is infused in SCID patient. The stem cells develop into functional immune
cells that can fight off infections.
Why is IVIG helpful in SCID? - CORRECT ANSWERS IVIG infuses antibodies from
healthy donors. SCID pts cannot make antibodies so IVIG help to prevent infections. Often
performed a couple times a week until the patient gets a bone marrow transplant.
What does SubQ adenosine deaminase enzyme replacement do for SCID - CORRECT
ANSWERS Gives pt ADA enzyme so their immune cells can survive and work better.
Pediatric Patient ACTUAL QUESTIONS
AND CORRECT ANSWERS
How do newborns receive passive immunity? - CORRECT ANSWERS placenta and
breastfeeding. They receive maternal antibodies
Young children tend to have larger what compared to adults? - CORRECT
ANSWERS lymph nodes, thymus, and tonsils
Difference between adaptive and innate immunity - CORRECT ANSWERS Innate acts
right away to protect body from threat. No memory of threat so will respond same in future. (use
macrophage)
Adaptive takes longer to react but more precise. Will remember the threat and respond faster and
stronger next time. (use B and T cells)
What labs will you draw if you want to know the specific count of WBC? - CORRECT
ANSWERS CBC with differential
what is passive immunity? - CORRECT ANSWERS Antibodies that are received from
external source such as (IVIG) intravenous immunoglobulin administration and placenta or
breastmilk
What is humoral immunity? Is it able to cross the placenta? If so, in what form? - CORRECT
ANSWERS B cell lymphocytes that secrete antibodies that binds and recognize antigens.
When binding together, it will recognize the foreign cell and neutralize it. It can cross the
placenta as IgG.
, What is cellular immunity? Can it cross placenta? - CORRECT ANSWERS T-cell
lymphocytes attacks infected or foreign cells. Does not recognize antigens or cross placenta.
What is SCID? - CORRECT ANSWERS severe combined immunodeficiency, an
autosomal recessive disorder where the baby is born with no T or B cell protection
What are common assessment findings of SCID? - CORRECT ANSWERS - Severe or
recurrent infections
- inability to thrive (poor growth or weight gain due to repeated infections and nutrient
absorption issues)
- diarrhea and vomiting (lead to dehydration and malnutrition)
How is SCID treated - CORRECT ANSWERS - bone marrow transplant
- IVIG infusions,
-Subq adenosine deaminase enzyme replacement
- long term antibiotic therapy, - gene therapy developments
How does a bone marrow transplant help with SCID? - CORRECT ANSWERS Stem cells
from a healthy donor is infused in SCID patient. The stem cells develop into functional immune
cells that can fight off infections.
Why is IVIG helpful in SCID? - CORRECT ANSWERS IVIG infuses antibodies from
healthy donors. SCID pts cannot make antibodies so IVIG help to prevent infections. Often
performed a couple times a week until the patient gets a bone marrow transplant.
What does SubQ adenosine deaminase enzyme replacement do for SCID - CORRECT
ANSWERS Gives pt ADA enzyme so their immune cells can survive and work better.
