BIOL 2153 Genetics all exam 2 combined (TEST
BANK) 2025 Louisiana State University
Exam #2 (Grade 1) for Principles of Genetics, Fall Term 2024, Section 7-10.
Bubble in your name and student identification number on SIDE TWO of the
scantron. Also, you need to mark in the grade section whether your exam is Grade 1
or 2. The correct answer for each question will be awarded 3 points (3 x 33 = 99)
and one extra point will be added to make 100 point. Keep this exam booklet and
bring it to your next discussion session, when the exam will be reviewed.
(Q1-5) The following karyotypes represent the combinations of human
chromosomes.
The letter O in karyotyping means no chromosome.
A. (46, XX) B. (46, XY) C. (23, Y) D. (23, X) E. (24, XX) F. (22, O)
1. Among the combinations shown above, which ones represent normal male and
female, respectively?
a. A and B
b. B and A
c. A and C
d. B and C
e. B and D
2. Among the combinations shown above, which one is the impossible karyotype?
a. sperm with C type
b. sperm with D type
c. egg with C type
d. egg with D type
e. egg with E type
3. Which fertilization likely results in individuals with Klinefelter syndrome?
a. sperm with D type and egg with D type
b. sperm with C type and egg with D type
c. sperm with C type and egg with E type
d. sperm with D type and egg with E type
e. sperm with D type and egg with F type
4. Which fertilization likely results in individuals with Turner syndrome?
a. sperm with D type and egg with D type
b. sperm with C type and egg with D type
c. sperm with C type and egg with E type
d. sperm with D type and egg with E type
e. sperm with D type and egg with F type
5. Which fertilization likely results in individuals with two Barr bodies?
a. sperm with D type and egg with D type
b. sperm with C type and egg with D type
c. sperm with C type and egg with E type
d. sperm with D type and egg with E type
e. sperm with D type and egg with F type
1
,(Q6-7) A group of scientists performed a transgenic experiment to test the potential
function of the SRY gene with the mouse as a model organism, as shown in the
picture below.
6. How did they generate the mouse with XX+SRY?
a. Mutant form of SRY was inserted into the fertilized
female egg.
b. Normal form of SRY was inserted into the fertilized
female egg.
c. Mutant form of SRY was inserted into the fertilized
male egg.
d. Normal form of SRY was inserted into the fertilized
male egg.
e. none of the above
7. Which statement is INCORRECT about the outcome of this experiment?
a. The mouse with XX+SRY exhibits the morphological features of male, such as the
distant separation of the two holes representing the reproductive and digestive
holes.
b. The mouse with XX+SRY has testes as a female.
c. SRY is responsible for the development of testes during embryogenesis.
d. SRY also encodes an enzyme that produces the male sex hormone, testosterone.
e. As an outcome, SRY is responsible for all the features of maleness.
(Q8-11) In domesticated cats, one locus in X chromosome is responsible for coat
color variations: B allele for orange color and b allele for black color. We have a set
of 6 cats with the following genotypes:
Cat 1 (XBY) Cat 2 (XbY) Cat 3 (XBXbY)
Cat 4 (XBXB) Cat 5 (XbXb) Cat 6 (XBXb)
8. Which cats have a mosaic pattern of coat color with orange and black?
a. Cat 2 and 3
b. Cat 3 and 4
c. Cat 4 and 5
d. Cat 5 and 6
e. Cat 3 and 6
9. Which cat does go through X chromosomal inactivation?
a. Cat 1 and 4
b. Cat 2 and 4
c. Cat 3 and 4
d. Cat 2 and 5
e. Cat 2 and 6
2
,10. Among the following pairs, which pair will produce the most number of male
kittens with orange color?
a. Cat 1 and 4
b. Cat 1 and 5
c. Cat 1 and 6
d. Cat 2 and 5
e. Cat 2 and 6
11. If we do breeding experiments with these cats, which pair will produce the least
numbers of kittens with the mosaic pattern of coat color?
a. Cat 1 and 4
b. Cat 1 and 5
c. Cat 1 and 6
d. Cat 2 and 4
e. Cat 2 and 6
(Q12-13) 12. A woman has the following genotype (A/a, B C/b c, D/d), and the two
genes, B and C, are located on a same chromosome. The genetic distance between
these two genes is close to 0%. Then, how many genetically different eggs can be
formed from this woman?
a. one
b. two
c. four
d. eight
e. sixteen
13. If the genetic distance between B and C is 50%, then how many genetically
different eggs can be formed from this woman?
a. one
b. two
c. four
d. eight
e. sixteen
14. Mendel used two traits of garden pea, color and shape, to derive Independent
Assortment Law. Let’s assume that the two genes responsible for Color (Yellow and
Green) and Shape (Round and Wrinkled) are located very close to each other on a
same chromosome, and that Yellow is dominant to Green, and Round is dominant to
Wrinkled. Let’s also assume that you have repeated the dihybrid experiment. The
pure-bred Yellow Round was crossed with the pure-bred Green Wrinkled, and later
the dihybrid F1 progeny with Yellow Round was self-crossed. Then, what would be
the phenotypic ratio of the F2 progeny?
a. Yellow Round 9: Yellow Wrinkled 3: Green Round 3: Green Wrinkled 1
b. Yellow Round 4: Yellow Wrinkled 4: Green Round 4: Green Wrinkled 4
c. Yellow Round 8: Yellow Wrinkled 0: Green Round 0: Green Wrinkled 8
3
, d. Yellow Round 12: Yellow Wrinkled 0: Green Round 0: Green Wrinkled 4
e. Yellow Round 9: Yellow Wrinkled 0: Green Round 3: Green Wrinkled 4
(Q15-18) In Drosophila, the recessive pr and cn mutations cause brown and bright-
red eyes, respectively. The wild-type flies have brick-red eyes. The double mutant
pr cn combination has orange eyes. A pure-bred female with brown eyes was
crossed to a pure-bred bright-red-eyed male. The F1 progeny from this cross was
further crossed with an orange-eyed fly. The progeny of this test cross has the
following distribution of eye colors:
wild-type 50
brown 150
bright-red 150
orange 50
400
15. Which classes are the parental types?
a. wild-type and orange
b. brown and bright-red
c. wild-type and brown
d. bright-red and orange
e. There is no way to determine this.
16. What is the genotype of the F1 progeny?
a. pr cn / pr+ cn+
b. pr+ cn / pr+ cn
c. pr+ cn / pr cn+
d. pr cn+ / pr cn+
e. pr cn / pr cn
17. What is the map distance between the pr and cn genes?
a. 2 %
b. 4 %
c. 10 %
d. 25 %
e. 50 %
18. Let’s assume that we have found another pure-bred female with brown eyes, but
with a paracentric inversion between pr and cn genes, and that we repeat another
series of breeding experiment as described above. Then, which phenotype
categories would not be detected easily among the F2 progeny?
a. wild-type and brown
b. brown and bright-red
4
BANK) 2025 Louisiana State University
Exam #2 (Grade 1) for Principles of Genetics, Fall Term 2024, Section 7-10.
Bubble in your name and student identification number on SIDE TWO of the
scantron. Also, you need to mark in the grade section whether your exam is Grade 1
or 2. The correct answer for each question will be awarded 3 points (3 x 33 = 99)
and one extra point will be added to make 100 point. Keep this exam booklet and
bring it to your next discussion session, when the exam will be reviewed.
(Q1-5) The following karyotypes represent the combinations of human
chromosomes.
The letter O in karyotyping means no chromosome.
A. (46, XX) B. (46, XY) C. (23, Y) D. (23, X) E. (24, XX) F. (22, O)
1. Among the combinations shown above, which ones represent normal male and
female, respectively?
a. A and B
b. B and A
c. A and C
d. B and C
e. B and D
2. Among the combinations shown above, which one is the impossible karyotype?
a. sperm with C type
b. sperm with D type
c. egg with C type
d. egg with D type
e. egg with E type
3. Which fertilization likely results in individuals with Klinefelter syndrome?
a. sperm with D type and egg with D type
b. sperm with C type and egg with D type
c. sperm with C type and egg with E type
d. sperm with D type and egg with E type
e. sperm with D type and egg with F type
4. Which fertilization likely results in individuals with Turner syndrome?
a. sperm with D type and egg with D type
b. sperm with C type and egg with D type
c. sperm with C type and egg with E type
d. sperm with D type and egg with E type
e. sperm with D type and egg with F type
5. Which fertilization likely results in individuals with two Barr bodies?
a. sperm with D type and egg with D type
b. sperm with C type and egg with D type
c. sperm with C type and egg with E type
d. sperm with D type and egg with E type
e. sperm with D type and egg with F type
1
,(Q6-7) A group of scientists performed a transgenic experiment to test the potential
function of the SRY gene with the mouse as a model organism, as shown in the
picture below.
6. How did they generate the mouse with XX+SRY?
a. Mutant form of SRY was inserted into the fertilized
female egg.
b. Normal form of SRY was inserted into the fertilized
female egg.
c. Mutant form of SRY was inserted into the fertilized
male egg.
d. Normal form of SRY was inserted into the fertilized
male egg.
e. none of the above
7. Which statement is INCORRECT about the outcome of this experiment?
a. The mouse with XX+SRY exhibits the morphological features of male, such as the
distant separation of the two holes representing the reproductive and digestive
holes.
b. The mouse with XX+SRY has testes as a female.
c. SRY is responsible for the development of testes during embryogenesis.
d. SRY also encodes an enzyme that produces the male sex hormone, testosterone.
e. As an outcome, SRY is responsible for all the features of maleness.
(Q8-11) In domesticated cats, one locus in X chromosome is responsible for coat
color variations: B allele for orange color and b allele for black color. We have a set
of 6 cats with the following genotypes:
Cat 1 (XBY) Cat 2 (XbY) Cat 3 (XBXbY)
Cat 4 (XBXB) Cat 5 (XbXb) Cat 6 (XBXb)
8. Which cats have a mosaic pattern of coat color with orange and black?
a. Cat 2 and 3
b. Cat 3 and 4
c. Cat 4 and 5
d. Cat 5 and 6
e. Cat 3 and 6
9. Which cat does go through X chromosomal inactivation?
a. Cat 1 and 4
b. Cat 2 and 4
c. Cat 3 and 4
d. Cat 2 and 5
e. Cat 2 and 6
2
,10. Among the following pairs, which pair will produce the most number of male
kittens with orange color?
a. Cat 1 and 4
b. Cat 1 and 5
c. Cat 1 and 6
d. Cat 2 and 5
e. Cat 2 and 6
11. If we do breeding experiments with these cats, which pair will produce the least
numbers of kittens with the mosaic pattern of coat color?
a. Cat 1 and 4
b. Cat 1 and 5
c. Cat 1 and 6
d. Cat 2 and 4
e. Cat 2 and 6
(Q12-13) 12. A woman has the following genotype (A/a, B C/b c, D/d), and the two
genes, B and C, are located on a same chromosome. The genetic distance between
these two genes is close to 0%. Then, how many genetically different eggs can be
formed from this woman?
a. one
b. two
c. four
d. eight
e. sixteen
13. If the genetic distance between B and C is 50%, then how many genetically
different eggs can be formed from this woman?
a. one
b. two
c. four
d. eight
e. sixteen
14. Mendel used two traits of garden pea, color and shape, to derive Independent
Assortment Law. Let’s assume that the two genes responsible for Color (Yellow and
Green) and Shape (Round and Wrinkled) are located very close to each other on a
same chromosome, and that Yellow is dominant to Green, and Round is dominant to
Wrinkled. Let’s also assume that you have repeated the dihybrid experiment. The
pure-bred Yellow Round was crossed with the pure-bred Green Wrinkled, and later
the dihybrid F1 progeny with Yellow Round was self-crossed. Then, what would be
the phenotypic ratio of the F2 progeny?
a. Yellow Round 9: Yellow Wrinkled 3: Green Round 3: Green Wrinkled 1
b. Yellow Round 4: Yellow Wrinkled 4: Green Round 4: Green Wrinkled 4
c. Yellow Round 8: Yellow Wrinkled 0: Green Round 0: Green Wrinkled 8
3
, d. Yellow Round 12: Yellow Wrinkled 0: Green Round 0: Green Wrinkled 4
e. Yellow Round 9: Yellow Wrinkled 0: Green Round 3: Green Wrinkled 4
(Q15-18) In Drosophila, the recessive pr and cn mutations cause brown and bright-
red eyes, respectively. The wild-type flies have brick-red eyes. The double mutant
pr cn combination has orange eyes. A pure-bred female with brown eyes was
crossed to a pure-bred bright-red-eyed male. The F1 progeny from this cross was
further crossed with an orange-eyed fly. The progeny of this test cross has the
following distribution of eye colors:
wild-type 50
brown 150
bright-red 150
orange 50
400
15. Which classes are the parental types?
a. wild-type and orange
b. brown and bright-red
c. wild-type and brown
d. bright-red and orange
e. There is no way to determine this.
16. What is the genotype of the F1 progeny?
a. pr cn / pr+ cn+
b. pr+ cn / pr+ cn
c. pr+ cn / pr cn+
d. pr cn+ / pr cn+
e. pr cn / pr cn
17. What is the map distance between the pr and cn genes?
a. 2 %
b. 4 %
c. 10 %
d. 25 %
e. 50 %
18. Let’s assume that we have found another pure-bred female with brown eyes, but
with a paracentric inversion between pr and cn genes, and that we repeat another
series of breeding experiment as described above. Then, which phenotype
categories would not be detected easily among the F2 progeny?
a. wild-type and brown
b. brown and bright-red
4
