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A patient with metabolic alkalosis and partial respiratory
compensation - ANSWER-will have symptoms of fatigue, cool
pale hands and feet, a new-onset systolic heart murmur, and
vomiting coffee-ground looking material.
Hypokalemia - ANSWER-will increase digoxin toxicity
Endocrinology:
Hyperparathyroidism - ANSWER-can cause secondary renal
failure
Primary hyperparathyroidism - ANSWER-Excess secretion of
PTH from one or more parathyroid glands; is typically caused
by a tumor in the parathyroid gland.
Hyperglycemia - ANSWER-can occur with increased
release of cortisol,
epinephrine, glucagon, and growth hormone into the
bloodstream.
,Hypoglycemia - ANSWER-can be caused by starvation and
intense exercise
A patient with Type I diabetes who exercises heavily -
ANSWER-may have symptoms of hunger, headache,
lightheadedness, confusion, tachycardia, and pallor due to
hypoglycemia.
Obesity is a risk factor for - ANSWER-developing Type 2
diabetes because of
increased insulin
resistance
Glucagon - ANSWER-A protein hormone secreted by pancreatic
endocrine cells that raises blood glucose levels; an
antagonistic hormone to insulin; stimulates glycogenolysis by
the liver
Dawn phenomenon (Dawn Effect) - ANSWER-occurs in the early
morning hours
(i.e., between 2 am and 8 am); blood glucose levels increase
in patients with
diabetes. There is no nighttime
hypoglycemia
Somogyi effect - ANSWER-If a client fails to eat her bedtime
snack she might experience the Somogyi effect. This abrupt
drop in the client's blood glucsose level during the night is
followed by a false elevation;
,Occurs after an episode of untreated nightime hypoglycemia,
causing increased blood glucose levels in the morning; treated
by increasing food intake near bedtime or reducing the evening
insulin dose.
Gastrointestinal:
Laxatives - ANSWER-stimulants (e.g., senna, Bisacodyl,
magnesium oxide [milk of magnesia], magnesium citrate,
castor oil), bulk (psyllium, methylcellulose), stool softeners
(e.g., docusate), sugars (e.g., lactulose), osmotic agent trapping
water in the GI lumen (e.g., polyethylene glycol), mineral oil.
Linaclotide (Linzess) - ANSWER-IBS-*C* Therapy; for
chronic idiopathic
constipation
(CIC)
The safest laxative for chronic use is - ANSWER-
methylcellulose (Citrucel,
Metamucil)
Octreotide - ANSWER-is a potent vasoconstrictor used in
treating acute GI
bleeds
Anti-emetic agents - ANSWER-antihistamines, phenothiazines
(e.g.
prochlorperazine), 5HT3 receptor antagonists (e.g.,
ondansetron[Zofran], granisetron).
, Ondansetron (Zofran) - ANSWER-Antiemetic; can cause
constipation,
headache, heart conduction irregularities
(prolonged QT interval).
5HT3 receptor antagonists - ANSWER-inhibit serotonin
receptors inside the
chemoreceptor trigger zone (CTZ) and also inhibit serotonin
receptors on vagal
nerve terminals; these pharmacologic actions reduce
nausea and vomiting.
H2RAs - ANSWER-cimetidine (Tagamet), ranitidine
(Zantac), famotidine
(Pepcid), nizatidine
(Axid)
Lactulose - ANSWER-is used in hepatic encephalopathy; works
by ion trapping
of
ammonia.
Proton Pump Inhibitors (PPIs) - ANSWER-esomeprazole
(Nexium), lansoprazole (Prevacid), omeprazole (Prilosec),
pantoprazole (Protonix), rabeprazole (Aciphex)
Heart patients taking clopidogrel (Plavix) - ANSWER-should
avoid omeprazole;