PHARM EXAM I ||NEWEST EXAM
UPDATE|| QUESTIONS AND
ANSWERS||STUDY NOW
In people with heart failure, the best drugs for reducing excessive sympathetic
stimulation of the failing heart are
CORRECT ANSWER s:
a. diuretics
b. angiotensin II receptor blockers
c. calcium channel blockers
d. beta blockers
e. alpha blockers -CORRECT ANSWER d. beta blockers
An antiarrhythmic drug used to treat bradycardia inadvertently creates tachycardia. The
most likely reason is that this drug causes _____ of the ______.
CORRECT ANSWER s:
a. excitation; bundle of His
b. excitation; sinoatrial node
c. inhibition; bundle of His
d. inhibition; sinoatrial node
e. inhibition; atrioventricular node -CORRECT ANSWER b. excitation; sinoatrial node
Depending on the dose and route of administration, lidocaine and similar drugs can be
used as local anesthetics or cardiac antiarrhythmic drugs because these drugs affect
the excitability of _____ ion channels.
CORRECT ANSWER s:
a. calcium
b. chloride
c. potassium
d. magnesium
e. sodium -CORRECT ANSWER e. sodium
Angiotensin converting enzyme (ACE) inhibitors can help _____ blood pressure by
_____ the formation of angiotensin II.
CORRECT ANSWER s:
a. increase; increasing
b. increasing; decreasing
c. decreasing; increasing
d. decrease; decreasing
e. none of the above are true -CORRECT ANSWER b. increasing; decreasing
Drug management in hemophilia consists of giving drugs that
CORRECT ANSWER s:
a. inhibit platelet function.
,b. treatment consists of administering the missing clotting factor(s)
c. inhibit thrombin formation.
d. increase fibrinolysin activity
e. inhibit Vitamin K activity -CORRECT ANSWER b. treatment consists of
administering the missing clotting factor(s)
Which of the following drug categories is NOT used to treat cardiac arrhythmias?
CORRECT ANSWER s:
a. calcium channel blockers
b. chloride channel blockers
c. sodium channel blockers
d. drugs that prolong cardiac repolarization
e. beta blockers -CORRECT ANSWER b. chloride channel blockers
All of the following types of drugs will decrease cardiac workload in people with heart
failure EXCEPT
CORRECT ANSWER s:
a. beta blockers
b. angiotensin converting enzyme (ACE) inhibitors
c. vasodilators
d. alpha-1 stimulants
e. diuretics -CORRECT ANSWER alpha-1 stimulants
Certain beta-blockers such as pindolol and acebutolol are valuable because they block
the effects of excessive endogenous catecholamines while still producing a normal
background level of sympathetic stimulation to the heart. These beta blockers are said
to have
CORRECT ANSWER s:
a. intrinsic sympathomimetic activity
b. selective sympatholytic activity
c. extrinsic sympatholytic activity
d. nonselective sympatholytic activity
e. intrinsic sympatholytic activity -CORRECT ANSWER a. intrinsic sympathomimetic
activity
Low molecular weight heparins such as enoxaparin are often preferred to more
traditional (unfractionated) heparin because low molecular weight heparins
CORRECT ANSWER s:
a. can be administered subcutaneously
b. usually do not need to be administered as frequently as traditional heparin
c. provide more predictable anticoagulant effects
d. all the above are true
e. none of the above are true -CORRECT ANSWER d. all the above are true
Beta blockers are said to be cardioselective if they bind preferentially to
CORRECT ANSWER s:
, a. all the above are true
b. beta-1 receptors
c. beta-3 receptors
d. beta-2 receptors -CORRECT ANSWER b. beta-1 receptors
The half life of a drug taken once a day is about
CORRECT ANSWER s: a.
3-1/2 days
b.
14 days
c.
1 day
d.
7 days -CORRECT ANSWER d.
7 days
Biotransformation, one method of drug inactivation, occurs by which of the following
processes:
CORRECT ANSWER s: a.
Elimination, reduction, hydrolysis, and conjugation
b.
Oxidation, reduction, hydrolysis, and conjugation
c.
Transformation, oxidation, reduction and hydrolysis
d.
Oxidation, excretion, elimination, and conjugation -CORRECT ANSWER b.
Oxidation, reduction, hydrolysis, and conjugation
Awareness of drug interactions are important because:
CORRECT ANSWER s: a.
One drug may cancel the other's effect
b.
One drug may cost more than the other
c.
The drugs may act in synergy
d.
A and C are correct -CORRECT ANSWER d.
A and C are correct
An agonist drug
CORRECT ANSWER s: a.
Acts by promoting up-regulation on the surface of cells
b.
Acts to decrease the action of a natural receptor chemical
c.
Blocks a receptor to prevent a natural receptive chemical from binding
UPDATE|| QUESTIONS AND
ANSWERS||STUDY NOW
In people with heart failure, the best drugs for reducing excessive sympathetic
stimulation of the failing heart are
CORRECT ANSWER s:
a. diuretics
b. angiotensin II receptor blockers
c. calcium channel blockers
d. beta blockers
e. alpha blockers -CORRECT ANSWER d. beta blockers
An antiarrhythmic drug used to treat bradycardia inadvertently creates tachycardia. The
most likely reason is that this drug causes _____ of the ______.
CORRECT ANSWER s:
a. excitation; bundle of His
b. excitation; sinoatrial node
c. inhibition; bundle of His
d. inhibition; sinoatrial node
e. inhibition; atrioventricular node -CORRECT ANSWER b. excitation; sinoatrial node
Depending on the dose and route of administration, lidocaine and similar drugs can be
used as local anesthetics or cardiac antiarrhythmic drugs because these drugs affect
the excitability of _____ ion channels.
CORRECT ANSWER s:
a. calcium
b. chloride
c. potassium
d. magnesium
e. sodium -CORRECT ANSWER e. sodium
Angiotensin converting enzyme (ACE) inhibitors can help _____ blood pressure by
_____ the formation of angiotensin II.
CORRECT ANSWER s:
a. increase; increasing
b. increasing; decreasing
c. decreasing; increasing
d. decrease; decreasing
e. none of the above are true -CORRECT ANSWER b. increasing; decreasing
Drug management in hemophilia consists of giving drugs that
CORRECT ANSWER s:
a. inhibit platelet function.
,b. treatment consists of administering the missing clotting factor(s)
c. inhibit thrombin formation.
d. increase fibrinolysin activity
e. inhibit Vitamin K activity -CORRECT ANSWER b. treatment consists of
administering the missing clotting factor(s)
Which of the following drug categories is NOT used to treat cardiac arrhythmias?
CORRECT ANSWER s:
a. calcium channel blockers
b. chloride channel blockers
c. sodium channel blockers
d. drugs that prolong cardiac repolarization
e. beta blockers -CORRECT ANSWER b. chloride channel blockers
All of the following types of drugs will decrease cardiac workload in people with heart
failure EXCEPT
CORRECT ANSWER s:
a. beta blockers
b. angiotensin converting enzyme (ACE) inhibitors
c. vasodilators
d. alpha-1 stimulants
e. diuretics -CORRECT ANSWER alpha-1 stimulants
Certain beta-blockers such as pindolol and acebutolol are valuable because they block
the effects of excessive endogenous catecholamines while still producing a normal
background level of sympathetic stimulation to the heart. These beta blockers are said
to have
CORRECT ANSWER s:
a. intrinsic sympathomimetic activity
b. selective sympatholytic activity
c. extrinsic sympatholytic activity
d. nonselective sympatholytic activity
e. intrinsic sympatholytic activity -CORRECT ANSWER a. intrinsic sympathomimetic
activity
Low molecular weight heparins such as enoxaparin are often preferred to more
traditional (unfractionated) heparin because low molecular weight heparins
CORRECT ANSWER s:
a. can be administered subcutaneously
b. usually do not need to be administered as frequently as traditional heparin
c. provide more predictable anticoagulant effects
d. all the above are true
e. none of the above are true -CORRECT ANSWER d. all the above are true
Beta blockers are said to be cardioselective if they bind preferentially to
CORRECT ANSWER s:
, a. all the above are true
b. beta-1 receptors
c. beta-3 receptors
d. beta-2 receptors -CORRECT ANSWER b. beta-1 receptors
The half life of a drug taken once a day is about
CORRECT ANSWER s: a.
3-1/2 days
b.
14 days
c.
1 day
d.
7 days -CORRECT ANSWER d.
7 days
Biotransformation, one method of drug inactivation, occurs by which of the following
processes:
CORRECT ANSWER s: a.
Elimination, reduction, hydrolysis, and conjugation
b.
Oxidation, reduction, hydrolysis, and conjugation
c.
Transformation, oxidation, reduction and hydrolysis
d.
Oxidation, excretion, elimination, and conjugation -CORRECT ANSWER b.
Oxidation, reduction, hydrolysis, and conjugation
Awareness of drug interactions are important because:
CORRECT ANSWER s: a.
One drug may cancel the other's effect
b.
One drug may cost more than the other
c.
The drugs may act in synergy
d.
A and C are correct -CORRECT ANSWER d.
A and C are correct
An agonist drug
CORRECT ANSWER s: a.
Acts by promoting up-regulation on the surface of cells
b.
Acts to decrease the action of a natural receptor chemical
c.
Blocks a receptor to prevent a natural receptive chemical from binding
