voltage- gated Na+ channel - correct answer✔✔A Na+- selective channel that opens or
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closes in response to changes in the voltage of the local membrane potential; it mediates the
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action potential. Compare ligand- gated ion channel.
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Depolarization - correct answer✔✔A decrease in membrane potential (the interior of the ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
neuron becomes less negative) ||\\//|| ||\\//|| ||\\//||
Hyperpolarization - correct answer✔✔An increase in membrane potential (the interior of ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
the neuron becomes even more negative).
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Basal forebrain - correct answer✔✔A region, ventral to the basal ganglia, that is the major
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source of ACH in the brain and has been implicated in sleep.
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Calcium Ion - correct answer✔✔A calcium atom that carries a double positive charge ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
because it has lost two electrons ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
Choline acetyltransferease (ChAT) - correct answer✔✔An important enzyme involved in
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the synthesis of the neurotransmitter acetylcholine.
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Cholinergic - correct answer✔✔Referring to the cells that use acetylcholine as their ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
synaptic transmitter. ||\\//||
Muscarinic - correct answer✔✔Referring to cholinergic receptors that respond to the ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
chemical muscarine as well as to A Ch. Muscarinic receptors mediate chiefly the inhibitory ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
activities of A Ch. ||\\//|| ||\\//|| ||\\//||
,EEG - correct answer✔✔Recording and study of gross electrical activity of the brain via
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large electrodes placed on the scalp.
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Ligand - correct answer✔✔A substance that binds to receptor molecules, such as a
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neurotransmitter or drug that binds post-synaptic receptors. ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
Ion channel - correct answer✔✔A pore in the cell membrane that permits the passage of
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certain ions through the membrane when the channels are open.
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Ionotropic receptor - correct answer✔✔Also called ligand-gated ion channel. A receptor ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
protein containing an ion channel that open when the receptor is bound by an agonist.
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Metabotropic receptor - correct answer✔✔A receptor protein that does not contain ion ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
channels but may, when activated, use a G protein system to open nearby ion channels or to
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produce other cellular effects.
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Diffusion - correct answer✔✔The spontaneous spread of molecules until a uniform ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
concentration is achieved. ||\\//|| ||\\//||
Electrostatic gradient - correct answer✔✔Electrostatic pressure is the propensity of charged ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
molecules or ions to move, via diffusion toward areas with the opposite charge.
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Cation - correct answer✔✔a positively charged ion, such as a potassium or sodium ion.
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Anion - correct answer✔✔a negatively charged ion
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Chloride Ion (CI-) - correct answer✔✔a chlorine atom that carries a negative charge||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
because it has gained one electron. ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
, Conduction zone - correct answer✔✔The part of a neuron over which the nerve's electrical ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
signal may be actively propagated. This zone usually corresponds to the cell's axon.
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Convergence - correct answer✔✔The phenomenon of neural connection in which many ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
cells send signals to a single cell.
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Electric potential across the neuron membrane - correct answer✔✔o More negative interior
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compared to exterior
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o Neuron's resting potential
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Resting Potential - correct answer✔✔A difference in electrical potential across the
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membrane of a nerve cell during an inactive period. ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
Reuptake - correct answer✔✔The process by which is released synaptic transmitter ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
molecules are taken up and reused by the presynaptic neuron, thus stopping synaptic ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
activity.
What happens during an action potential? - correct answer✔✔Spike: a rapid reversal of the
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membrane potential that monumentally makes the inside of the membrane positive with ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
respect to the outside. ||\\//|| ||\\//|| ||\\//||
o Refractory phase - correct answer✔✔A period during and after a nerve impulse in which
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the responsiveness of he axonal membrane is reduced. A brief period of complete
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insensitivity to stimuli (absolute refractory phase) is followed by a longer period of reduced ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
sensitivity (relative refractory phase) during which only strong stimulation produces an ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//|| ||\\//||
action potential. ||\\//||
o Absolute refractory period - correct answer✔✔A brief period of complete insensitivity to
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stimuli