Defences against Pathogens Exam
With answers
Give four examples of primary non-specific defences against pathogens in animals - answer-
skin, blood clotting, mucous, expulsive reflexes
What is the outer layer of skin called? - answer-epidermis
What are keratinocytes? - answer-epidermal cells that produce keratin
What % of cells in the epidermis are keratinocytes? - answer-90%
How and where are keratinocytes produced? - answer-by mitosis at the base of the epidermis
True or false: keratinocytes migrate out to the skins surface but die by the time they get there -
answer-true
What is the process called whereby the cytoplasm of keratinocytes dries out and replaced by
keratin-causing the cells to die? - answer-keratinisation
What protein is exposed when damage to a blood vessel occurs? - answer-collagen
What does exposed collagen from the vessel wall cause platelets to do? - answer-attract to the
collagen and become active platelets
Give the equation that produces thrombin enzymes - answer-thromboplastin -> prothrombin ->
thrombin
What two substances aid the production of prothrombin from thrombin? - answer-vitamin k and
calcium
What reaction does the thrombin enzyme catalyse? - answer-the formation of insoluble fibrin
from soluble fibrinogen
What is the function of fibrin in a blood clot? - answer-it creates fibres to hold a scab together
What three substances make up a scab? - answer-fibrin, platelets, red blood cells
What are the four steps when repairing skin under a scab? - answer-a deposition of fibrous
collagen is created, stem cells divide by mitosis to form new cells and migrate to the edges of
the cut to differentiate, new blood vessels grow and the tissue contracts to draw the edges of
the cut together and the scab is released