NUR 210 Principles of Pharmacology Exams Bundle
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Hydrochlorothiazide (HCTZ) - ...ANSWER...✓✓ Promotes
NA, K, and water excretion; acts on distal convoluted
renal tubule.
Uses of Hydrochlorothiazide - ...ANSWER...✓✓ Treat
hypertension and edema from heart failure.
Side effects of Hydrochlorothiazide - ...ANSWER...✓✓
Dizziness, headache, weakness, gastrointestinal distress,
photosensitivity.
Adverse reactions of Hydrochlorothiazide -
...ANSWER...✓✓ Fluid and electrolyte imbalances,
hyponatremia, hypotension, orthostatic hypotension,
hyperglycemia, hypokalemia, dysrhythmias.
Contraindications of Hydrochlorothiazide -
...ANSWER...✓✓ Renal failure, electrolyte depletion,
sulfonamide allergies.
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Caution with Hydrochlorothiazide - ...ANSWER...✓✓
Hepatic dysfunction, diabetes mellitus.
Interactions with Hydrochlorothiazide - ...ANSWER...✓✓
Increased digoxin toxicity with hypokalemia, anti-diabetic
drugs resulting in hyperglycemia, steroids causing
increased potassium loss.
Furosemide (Lasix) - ...ANSWER...✓✓ Inhibits water and
sodium reabsorption; potassium, magnesium, and
calcium are also excreted.
Uses of Furosemide - ...ANSWER...✓✓ Treat fluid
retention caused by heart failure, renal dysfunction,
cirrhosis, hypertension, and pulmonary edema.
Side effects of Furosemide - ...ANSWER...✓✓
Gastrointestinal distress, dizziness, weakness,
photosensitivity.
Adverse reactions of Furosemide - ...ANSWER...✓✓ Fluid
and electrolyte imbalances, hypokalemia, orthostatic
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hypotension, hypotension, hyperglycemia, hearing loss
when IV pushing too fast.
Contraindications of Furosemide - ...ANSWER...✓✓
Severe electrolyte imbalance, hypovolemia, allergy to
sulfa drugs.
Caution with Furosemide - ...ANSWER...✓✓ Heart failure
and diabetes.
Mannitol - ...ANSWER...✓✓ Causes water, sodium,
chloride, potassium to be excreted through the kidneys.
Uses of Mannitol - ...ANSWER...✓✓ Decrease intracranial
pressure/cerebral edema, decrease intraocular pressure,
promote excretion of toxic substances; most often used
as an emergency medication.
Interactions with Mannitol - ...ANSWER...✓✓ Increased
bleeding with anticoagulants, increased potassium loss
with steroids, increased digoxin toxicity with hypokalemia.