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Advanced Pharmacology for the
AGACNP | Questions & Verified
Answers | 100% Correct | Grade A -
Chamberlain
Question:
What is alteplase dosing for an acute MI?
Answer:
For patients > 67kg, the total dose is 100mg : 15mg IV bolus followed by 50 mg
over 30 minutes and then 35mg over 60 minutes
Question:
What is alteplase dosing for acute ischemic stroke?
Answer:
0.9 mg/kg (max 90mg) over 60 minutes with 10% of dose given as initial
bolus
,Question:
What is the alteplase dosing for pulmonary embolism?
Answer:
100mg IV over 2 hours
Question:
What is the EMS dose of aspirin for a suspected STEMI?
Answer:
162-325mg
Question:
How does morphine help in a STEMI?
Answer:
venodilation reduces preload, arterial dilation reduces after load, reducing
cardiac oxygen demand
Question:
How does nitroprusside reduce acute severe hypertension?
Answer:
direct-acting vasodilator that relaxes smooth muscle of arterioles and veins.
, Question:
Does nitroprusside cause reflex tachycardia?
Answer:
nitroprusside is an arteriol dilator, but reflex tachycardia is minimal
Question:
What is a side effect of nitroprusside?
Answer:
Sodium and water retention, cyanide poisoning
Question:
What steps do you take to avoid cyanide poisoning with nitroprusside?
Answer:
Avoid rapid transfusion (faster than 5 mcg/kg per minute) and coadminister
thiosulfate