NSG 6005 Week 2 Quiz_ NSG 6005 Week 2 (Latest 2021): South University

NSG 6005 Week 2 Quiz (Latest 2021): South University Question 1. The elderly are at high risk of ADRs due to: Having greater muscle mass than younger adults, leading to higher volume of distribution The extensive studies that have been conducted on drug safety in this age group The blood-brain barrier being less permeable, requiring higher doses to achieve therapeutic effect Age-related decrease in renal function Question 2. The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the: Minimum adverse effect level Peak of action Onset of action Therapeutic range Question 3. Genetic polymorphisms account for differences in metabolism, including: Poor metabolizers (PMs) that lack a working enzyme Intermediate metabolizers (IMs) that have one working, wild-type allele and one mutant allele Extensive metabolizers (EMs), with two normally functioning alleles