11/9/25, 10:19 AM CHAPTER 4 NERVOUS SYSTEM FINAl
CHAPTER 4 NERVOUS SYSTEM FINAL EXAM 2025 -
2026 \LATEST UPDATE\COMPLETE QUESTIONS
AND ACCCRATE DETAILED ANSWERS \VERIFIED
100% GRADEDC A+
What is the first step in "Start with monotherapy (a single AED)."
epilepsy treatment strategy?
If monotherapy fails what is "Switch to an alternative monotherapy."
the next step?
If epilepsy is still uncontrolled "Combination therapy (≥2 AEDs), but with increased risk
after two monotherapies of side effects and interactions."
what is the next step?
What is the MHRA/CHM "Switching AEDs between brands can cause harm in epilepsy
(Nov 2017) warning on AED patients."
switching?
Which AEDs are Category 1 "Carbamazepine, Phenytoin, Phenobarbital, Primidone."
(same brand required)?
Which AEDs are Category 2 "Sodium Valproate, Lamotrigine, Clonazepam, Topiramate."
(clinical judgement needed
for brand consistency)?
Which AEDs are Category 3 "Gabapentin, Levetiracetam, Pregabalin, Ethosuximide."
(no need for brand
consistency)?
What is the pharmacist's role "Ensure the correct brand/manufacturer is supplied and
in AED brand switching? counsel on risks of switching."
Does brand consistency "No, it applies only to patients with epilepsy."
apply to AEDs used in non-
epilepsy conditions?
How often are antiepileptic "Twice daily."
drugs usually given?
,11/9/25, 10:19 AM CHAPTER 4 NERVOUS SYSTEM FINAl
Name the main drug in the "Brivaracetam."
racetam class used for
epilepsy.
Which sodium channel "Carbamazepine."
blocker is also available as
oxcarbazepine and
eslicarbazepine?
Which cannabis-derived drug "Cannabidiol."
is used in epilepsy?
Which antiepileptic drug "Cenobamate."
beginning with 'C' is used
for seizures?
Which AED is first-line "Ethosuximide."
for absence seizures?
Which AEDs are also used for "Gabapentin and Pregabalin."
neuropathic pain?
Which AED is known for use in "Lacosamide."
neuropathic pain and epilepsy
starting with L?
Which AED can cause severe "Lamotrigine."
skin reactions such as SJS
and TEN?
Which AED is a broad- "Levetiracetam."
spectrum option often used
as 1st line for focal and
generalised seizures?
Which AED is known as 'ON' "Perampanel."
for once nightly dosing?
Which AED is an older drug "Phenytoin (with Fosphenytoin as prodrug)."
with a narrow therapeutic
index and has a prodrug
form?
,11/9/25, 10:19 AM CHAPTER 4 NERVOUS SYSTEM FINAl Flashcards | Quizlet
Which newer AED starts "Rufinamide."
with R and is used in
refractory seizures?
Which AED is the most "Sodium Valproate."
teratogenic and used
cautiously?
Which AED is used as "Stiripentol."
adjunctive therapy in rare
epilepsies like Dravet
syndrome?
Which AED is a GABA "Tiagabine."
reuptake inhibitor?
Which AED is linked to cleft "Topiramate."
palate and eye disorders in
pregnancy?
Which AED is linked to "Vigabatrin."
encephalopathy and
vision disorders?
Which AED is a sulfonamide "Zonisamide."
derivative used in epilepsy?
Which diuretic can be used as "Acetazolamide."
an AED by inhibiting carbonic
anhydrase?
Name three barbiturate AEDs. "Phenobarbital, Primidone, Thiopental."
Name five benzodiazepines "Clobazam, Clonazepam, Diazepam, Lorazepam, Midazolam."
used as AEDs.
What is the main risk of AED "Teratogenicity (miscarriage and congenital
use in pregnancy? malformations, especially in 1st trimester)."
Which two AEDs are "Lamotrigine and Levetiracetam."
considered safer in
pregnancy?
Which AED is highly "Sodium Valproate."
teratogenic and
contraindicated in
pregnancy unless no
alternative?
https://quizlet.com/gb/1082109540/chapter-4-nervous-system-final-flash-cards/?funnelUUID=8f251b6b-90bd-421b-8236-ccff3ecced76 4/63
, 11/9/25, 10:19 AM CHAPTER 4 NERVOUS SYSTEM FINAl Flashcards | Quizlet
According to MHRA/CHM "Valproate, Carbamazepine, Phenytoin, Phenobarbital, Pregabalin,
which AEDs are high risk in Topiramate."
pregnancy?
What contraception advice is "Use highly effective contraception."
essential for women of
childbearing potential on
AEDs?
What is the advice for women "Do not stop suddenly; urgent referral to a specialist."
planning pregnancy while on
AEDs?
What supplement should be "High-dose folic acid to prevent neural tube defects."
offered in AED users planning
pregnancy?
What should women with "Seek urgent medical advice immediately."
epilepsy do if pregnancy is
unplanned while on AEDs?
Which register should "The UK Epilepsy & Pregnancy Register."
pregnant women with
epilepsy be notified to?
https://quizlet.com/gb/1082109540/chapter-4-nervous-system-final-flash-cards/?funnelUUID=8f251b6b-90bd-421b-8236-ccff3ecced76 5/63
CHAPTER 4 NERVOUS SYSTEM FINAL EXAM 2025 -
2026 \LATEST UPDATE\COMPLETE QUESTIONS
AND ACCCRATE DETAILED ANSWERS \VERIFIED
100% GRADEDC A+
What is the first step in "Start with monotherapy (a single AED)."
epilepsy treatment strategy?
If monotherapy fails what is "Switch to an alternative monotherapy."
the next step?
If epilepsy is still uncontrolled "Combination therapy (≥2 AEDs), but with increased risk
after two monotherapies of side effects and interactions."
what is the next step?
What is the MHRA/CHM "Switching AEDs between brands can cause harm in epilepsy
(Nov 2017) warning on AED patients."
switching?
Which AEDs are Category 1 "Carbamazepine, Phenytoin, Phenobarbital, Primidone."
(same brand required)?
Which AEDs are Category 2 "Sodium Valproate, Lamotrigine, Clonazepam, Topiramate."
(clinical judgement needed
for brand consistency)?
Which AEDs are Category 3 "Gabapentin, Levetiracetam, Pregabalin, Ethosuximide."
(no need for brand
consistency)?
What is the pharmacist's role "Ensure the correct brand/manufacturer is supplied and
in AED brand switching? counsel on risks of switching."
Does brand consistency "No, it applies only to patients with epilepsy."
apply to AEDs used in non-
epilepsy conditions?
How often are antiepileptic "Twice daily."
drugs usually given?
,11/9/25, 10:19 AM CHAPTER 4 NERVOUS SYSTEM FINAl
Name the main drug in the "Brivaracetam."
racetam class used for
epilepsy.
Which sodium channel "Carbamazepine."
blocker is also available as
oxcarbazepine and
eslicarbazepine?
Which cannabis-derived drug "Cannabidiol."
is used in epilepsy?
Which antiepileptic drug "Cenobamate."
beginning with 'C' is used
for seizures?
Which AED is first-line "Ethosuximide."
for absence seizures?
Which AEDs are also used for "Gabapentin and Pregabalin."
neuropathic pain?
Which AED is known for use in "Lacosamide."
neuropathic pain and epilepsy
starting with L?
Which AED can cause severe "Lamotrigine."
skin reactions such as SJS
and TEN?
Which AED is a broad- "Levetiracetam."
spectrum option often used
as 1st line for focal and
generalised seizures?
Which AED is known as 'ON' "Perampanel."
for once nightly dosing?
Which AED is an older drug "Phenytoin (with Fosphenytoin as prodrug)."
with a narrow therapeutic
index and has a prodrug
form?
,11/9/25, 10:19 AM CHAPTER 4 NERVOUS SYSTEM FINAl Flashcards | Quizlet
Which newer AED starts "Rufinamide."
with R and is used in
refractory seizures?
Which AED is the most "Sodium Valproate."
teratogenic and used
cautiously?
Which AED is used as "Stiripentol."
adjunctive therapy in rare
epilepsies like Dravet
syndrome?
Which AED is a GABA "Tiagabine."
reuptake inhibitor?
Which AED is linked to cleft "Topiramate."
palate and eye disorders in
pregnancy?
Which AED is linked to "Vigabatrin."
encephalopathy and
vision disorders?
Which AED is a sulfonamide "Zonisamide."
derivative used in epilepsy?
Which diuretic can be used as "Acetazolamide."
an AED by inhibiting carbonic
anhydrase?
Name three barbiturate AEDs. "Phenobarbital, Primidone, Thiopental."
Name five benzodiazepines "Clobazam, Clonazepam, Diazepam, Lorazepam, Midazolam."
used as AEDs.
What is the main risk of AED "Teratogenicity (miscarriage and congenital
use in pregnancy? malformations, especially in 1st trimester)."
Which two AEDs are "Lamotrigine and Levetiracetam."
considered safer in
pregnancy?
Which AED is highly "Sodium Valproate."
teratogenic and
contraindicated in
pregnancy unless no
alternative?
https://quizlet.com/gb/1082109540/chapter-4-nervous-system-final-flash-cards/?funnelUUID=8f251b6b-90bd-421b-8236-ccff3ecced76 4/63
, 11/9/25, 10:19 AM CHAPTER 4 NERVOUS SYSTEM FINAl Flashcards | Quizlet
According to MHRA/CHM "Valproate, Carbamazepine, Phenytoin, Phenobarbital, Pregabalin,
which AEDs are high risk in Topiramate."
pregnancy?
What contraception advice is "Use highly effective contraception."
essential for women of
childbearing potential on
AEDs?
What is the advice for women "Do not stop suddenly; urgent referral to a specialist."
planning pregnancy while on
AEDs?
What supplement should be "High-dose folic acid to prevent neural tube defects."
offered in AED users planning
pregnancy?
What should women with "Seek urgent medical advice immediately."
epilepsy do if pregnancy is
unplanned while on AEDs?
Which register should "The UK Epilepsy & Pregnancy Register."
pregnant women with
epilepsy be notified to?
https://quizlet.com/gb/1082109540/chapter-4-nervous-system-final-flash-cards/?funnelUUID=8f251b6b-90bd-421b-8236-ccff3ecced76 5/63
