High Yield Drugs COMLEX I ACTUAL
QUESTIONS AND CORRECT ANSWERS
1) What drugs can cause digitalis toxicity if they are used together - CORRECT
ANSWERS✅✅a. Amiodarone + Verapamil + Quinidine
b. Digitalis toxicity symptoms in acute setting= GI symptoms- anorexia, nausea, vomiting,
abdominal pain
c. Digitalis toxicity symptoms in chronic setting= neurological symptoms like weakness and
blindness
2) What is the DOC for nightmares in PTSD - CORRECT ANSWERS✅✅a. Prazosin
b. Prazosin is an -blocker most commonly used to manage BPH and used in the treatment of
nightmares caused by PTSD
3) What are the stimulant drugs used to treat ADHD - CORRECT ANSWERS✅✅a.
Methylphenidate + Amphetamines
b. Both have PH in the names
4) What drugs are safe to use in mothers with HTN - CORRECT ANSWERS✅✅a.
Hydralazine, Methyldopa, Labetalol, Nifedipine
b. "Hypertensive Moms Love Nifedipine"
5) What vaccine should patients who take Eculizumab receive - CORRECT
ANSWERS✅✅a. Vaccine against Neisseria meningitidis
b. Eculizumab is an anti-body against C5 and prevents it from cleaving C5 into C5a + C5b
c. W/o formation of C5a + C5b cannot form MAC complex "No MAC, cannot attack"
d. Note: patients who have terminal complement deficiency should also receive vaccine for
N. meningitidis
6) What is Eculizumab used to treat - CORRECT ANSWERS✅✅a. Paroxysmal Nocturnal
Hemoglobinuria
, 7) What is the drug of choice for leishmaniasis - CORRECT ANSWERS✅✅a. Na+
Stibogluconate or Amphotericin B
b. Transmitted by sand flies
8) How do you treat -blocker overdose - CORRECT ANSWERS✅✅a. Secure airway,
provide IV fluid, give atropine (1st line) if treatment refractory to atropine and still see
hypotension, give Glucagon (2nd line)
b. Symptoms of -blocker OD: bradycardia, hypotension, wheezing, hypoglycemia, delirium,
seizures, and cardiogenic shock
9) What is the DOC for prophylaxis against Leptospirosis - CORRECT ANSWERS✅✅a.
Doxycycline
10) What diuretic can worsen or cause gout - CORRECT ANSWERS✅✅a. Thiazides
11) What is the DOC for severe hypertriglyceridemia - CORRECT ANSWERS✅✅a.
Fibrates
12) What antiretroviral is recommended for neonates born to HIV+ mothers - CORRECT
ANSWERS✅✅a. AZT
13) What can be used as medical management of prolactinomas - CORRECT
ANSWERS✅✅a. Dopamine agonists
b. DA normally inhibits prolactin, so if give dopamine reuptake inhibitor will see prolactin
14) What is the drug of choice for acute viral or idiopathic pericarditis - CORRECT
ANSWERS✅✅a. NSAID + Colchicine
b. Colchicine given to decrease number of repeat episodes of pericarditis
c. 2nd line treatment besides NSAIDs are steroids
15) What is the DOC for mastitis - CORRECT ANSWERS✅✅a. Dicloxacillin, Nafcillin
b. MCC of mastitis is S. aureus
c. Symptoms: fever, UNILATERAL breast tenderness
QUESTIONS AND CORRECT ANSWERS
1) What drugs can cause digitalis toxicity if they are used together - CORRECT
ANSWERS✅✅a. Amiodarone + Verapamil + Quinidine
b. Digitalis toxicity symptoms in acute setting= GI symptoms- anorexia, nausea, vomiting,
abdominal pain
c. Digitalis toxicity symptoms in chronic setting= neurological symptoms like weakness and
blindness
2) What is the DOC for nightmares in PTSD - CORRECT ANSWERS✅✅a. Prazosin
b. Prazosin is an -blocker most commonly used to manage BPH and used in the treatment of
nightmares caused by PTSD
3) What are the stimulant drugs used to treat ADHD - CORRECT ANSWERS✅✅a.
Methylphenidate + Amphetamines
b. Both have PH in the names
4) What drugs are safe to use in mothers with HTN - CORRECT ANSWERS✅✅a.
Hydralazine, Methyldopa, Labetalol, Nifedipine
b. "Hypertensive Moms Love Nifedipine"
5) What vaccine should patients who take Eculizumab receive - CORRECT
ANSWERS✅✅a. Vaccine against Neisseria meningitidis
b. Eculizumab is an anti-body against C5 and prevents it from cleaving C5 into C5a + C5b
c. W/o formation of C5a + C5b cannot form MAC complex "No MAC, cannot attack"
d. Note: patients who have terminal complement deficiency should also receive vaccine for
N. meningitidis
6) What is Eculizumab used to treat - CORRECT ANSWERS✅✅a. Paroxysmal Nocturnal
Hemoglobinuria
, 7) What is the drug of choice for leishmaniasis - CORRECT ANSWERS✅✅a. Na+
Stibogluconate or Amphotericin B
b. Transmitted by sand flies
8) How do you treat -blocker overdose - CORRECT ANSWERS✅✅a. Secure airway,
provide IV fluid, give atropine (1st line) if treatment refractory to atropine and still see
hypotension, give Glucagon (2nd line)
b. Symptoms of -blocker OD: bradycardia, hypotension, wheezing, hypoglycemia, delirium,
seizures, and cardiogenic shock
9) What is the DOC for prophylaxis against Leptospirosis - CORRECT ANSWERS✅✅a.
Doxycycline
10) What diuretic can worsen or cause gout - CORRECT ANSWERS✅✅a. Thiazides
11) What is the DOC for severe hypertriglyceridemia - CORRECT ANSWERS✅✅a.
Fibrates
12) What antiretroviral is recommended for neonates born to HIV+ mothers - CORRECT
ANSWERS✅✅a. AZT
13) What can be used as medical management of prolactinomas - CORRECT
ANSWERS✅✅a. Dopamine agonists
b. DA normally inhibits prolactin, so if give dopamine reuptake inhibitor will see prolactin
14) What is the drug of choice for acute viral or idiopathic pericarditis - CORRECT
ANSWERS✅✅a. NSAID + Colchicine
b. Colchicine given to decrease number of repeat episodes of pericarditis
c. 2nd line treatment besides NSAIDs are steroids
15) What is the DOC for mastitis - CORRECT ANSWERS✅✅a. Dicloxacillin, Nafcillin
b. MCC of mastitis is S. aureus
c. Symptoms: fever, UNILATERAL breast tenderness
