Nurs 615 Exam 2 Broad Questions with Correct and
Confirmed Graded A+ Answers. Assured Pass.
Terms in this set (130)
Tricyclic Antidepressent Uses depression, anxiety, enuresis, neuopathic pain, insomnia, eating disorders
inhibit reuptake of NE & 5-HT at presynaptic neuron; also act
Tricyclic Antidepressent MOA
on histamine & ACh receptors
imipramine
Tricyclic Antidepressent Examples (Tofranil)
amitriptyline
(Elavil) doxepin
(Silenor)
Anticholinergic
Orthostatic
hypotension
Tricyclic Antidepressent Adverse Sedation (histamine
Effects effect)
Cardiac conduction abnormalities, sinus tachycardia
(cardiotoxicity), prolonger QT interval
↓ seizure threshold, narrow TI (overdose fatal)
Tardive dyskinesia, neuroleptic malignant syndrome (rare)
Contraindicated: cardiovascular disorders, glaucoma, BPH, urinary
Tricyclic Antidepressent Key retention, conduction disorders, anyone with suicide risk,
Points
uncontrolled epilepsy
Avoid in elderly (falls, confusion) and suicidal patients (fatal in overdose).
what baseline test is EKG
needed before starting a
TCA
Monamine Oxidase Ihhibitor treatment of resistent depression
(MAOI) Uses
Inhibit MAO enzyme (irreversible inactivation)→ prevents
Monamine Oxidase Ihhibitor breakdown of NE, DA, 5- HT (inc bioavailability) also prevent
(MAOI) MOA
breakdown of tyramine (which is a precursor to
neurotransmitters)
, Monamine Oxidase Ihhibitor phenelzine (Nardil), tranylcypromine (Parnate)
(MAOI) Examples
Danger: Hypertensive crisis with tyramine-containing foods
Monamine Oxidase Ihhibitor (aged cheese, dried/aged meats, pickles, soy sauce, fermented
(MAOI) Risk
foods, alcohol) or drugs that rise
BP
Confirmed Graded A+ Answers. Assured Pass.
Terms in this set (130)
Tricyclic Antidepressent Uses depression, anxiety, enuresis, neuopathic pain, insomnia, eating disorders
inhibit reuptake of NE & 5-HT at presynaptic neuron; also act
Tricyclic Antidepressent MOA
on histamine & ACh receptors
imipramine
Tricyclic Antidepressent Examples (Tofranil)
amitriptyline
(Elavil) doxepin
(Silenor)
Anticholinergic
Orthostatic
hypotension
Tricyclic Antidepressent Adverse Sedation (histamine
Effects effect)
Cardiac conduction abnormalities, sinus tachycardia
(cardiotoxicity), prolonger QT interval
↓ seizure threshold, narrow TI (overdose fatal)
Tardive dyskinesia, neuroleptic malignant syndrome (rare)
Contraindicated: cardiovascular disorders, glaucoma, BPH, urinary
Tricyclic Antidepressent Key retention, conduction disorders, anyone with suicide risk,
Points
uncontrolled epilepsy
Avoid in elderly (falls, confusion) and suicidal patients (fatal in overdose).
what baseline test is EKG
needed before starting a
TCA
Monamine Oxidase Ihhibitor treatment of resistent depression
(MAOI) Uses
Inhibit MAO enzyme (irreversible inactivation)→ prevents
Monamine Oxidase Ihhibitor breakdown of NE, DA, 5- HT (inc bioavailability) also prevent
(MAOI) MOA
breakdown of tyramine (which is a precursor to
neurotransmitters)
, Monamine Oxidase Ihhibitor phenelzine (Nardil), tranylcypromine (Parnate)
(MAOI) Examples
Danger: Hypertensive crisis with tyramine-containing foods
Monamine Oxidase Ihhibitor (aged cheese, dried/aged meats, pickles, soy sauce, fermented
(MAOI) Risk
foods, alcohol) or drugs that rise
BP
