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Donepezil (Aricept)
Medication used to treat dementia. Does not cure, only slows
progression. Improves memory, focus, and ability to function. Enzyme
blocker works by restoring the balance of natural neurotransmitters in
the brain. Cholinesterase inhibitor that increases the concentration of
acetylcholine. Acetylcholine is needed for intact memory and for
learning.
Acetylcholine
Neurotransmitter affected by Alzheimer's Disease in the prefrontal
cortex
Confabulation
therapeutic fibbing
2 weeks
How long it takes for Donepezil (Aricept) to start working.
Cortical Dementia
Damage primarily affects the brain's cortex or outer layer. Causes
problems with memory, language, thinking and social behavior.
Subcortical Dementia
Affects parts of the brain below the cortex. Causes changes in emotions
and movement in addition to problems with memory.
Progressive Dementia
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Type of dementia that gets worse over time. No set path that every
patient follows. Will eventually interfere with more cognitive abilities
and ADLs.
Primary Dementia
Refers to the place of origin. Dementia that is not the result of any other
disease. AD.
Alzheimer's Dementia (AD)
Primary dementia that is incurable, irreversible and fatal. Caused by the
presence of a beta-amyloid protein in the neurons resulting in senile
plaques.
Secondary Dementia
Dementia that occurs as a result of another physical disease or injury.
Delirium
a state of temporary but acute mental confusion, signs; anxiety, tremors,
hallucinations, delusions, attention problems, a decline in the level of
consciousness, memory problems. A disturbance of consciousness and
cognition that develops over a short period is secondary to a medical
condition. Worsen at night. Risk of self-harm. Do not ask for rational
explanations. Do not restrain them. Treat them as adults.
Cholinesterase inhibitors
A class of drugs to treat people with dementia that help increase levels
of acetylcholine in the brain. Used in mild to moderate dementia.
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Normal Pressure Hydrocephalus
Excessive CSF occurs in the ventricles, with normal or slightly elevates
CSF pressure. As the fluid builds up it causes the ventricles to enlarge
and the pressure inside the head to increase, compressing brain tissues
and leading to neuro complications. Triad of symptoms are dementia,
urinary incontinence and gait deviation. Relieving the cause and the
symptoms are usually reversed.
Mild Alzheimer's
Memory loss of recent events. Difficulty remembering newly learned
information. Asking the same question over and over. Difficulty with
problem solving, complex tasks and sound judgement. Planning a family
event of balancing a check book. Changes in personality. May become
subdues or withdrawn especially in social situations or show
uncharacteristic irritability or anger. Reduced motivation to complete
tasks. Difficulty organizing and expressing thoughts. Finding the right
words to describe objects or clearly express ideas. Getting lost of
misplacing belongings. Increasing difficulty finding their ways around,
even in familiar places. Common to lose or misplace things, including
valuable items.
Moderate Dementia
Increasingly poor judgement and deepening confusion. May lose track
of where they are, day of the week, season. Man confuse family
members, close friends with strangers. May wander making it unsafe to
leave them alone. Forget details of their personal history like address,
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