NSC 830 Advanced Pharmacology – 2025/2026
Updated Study Guide & Practice Questions |
100% Pass Guarantee
Narrow Specturm - correct answerTreat limited # of organisms, Less likely to disrupt
normal flora, organism identified.
Broad Specturm - correct answerTreats multiple organisms, more likely to disrupt
normal flora, causative agent unknown.
Why would you select abx? - correct answerIs antimicrobial therapy indicated, make a
clinical diagnosis, collection of specimens for a cx or lab test, make microbial diagnosis,
select drug.
Extended spectrum - correct answertreats multiple organisms, more likely to disrupt
normal flora, used when causative organism is unknown.
Gram positive - correct answerPurple, thick layer
Example of gram positive - correct answerGroup A beta-strep
Strep PNA
Gram negative - correct answerRed or pink, thin layer
Example of gram negative - correct answerH. influenza
N. Gonoccocus
Atypical Organism - correct answercolorless, no layer
Example of Atypical organism - correct answerMacrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-lactum abx - correct answerTrue
Risk factors for Drug Resistant Strep PNA (DRSP) - correct answerRecent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day long term).
, Treatment for Drug Resistant Strep PNA - correct answerHigh dose amoxicillin 3-4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... - correct answerAllergy history (PCN- risk
of cross allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? - correct answertetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or baceriostiatic? - correct
answerBactericidals
What are bactericidals? - correct answerKills bacteria
What are bacteriostatic? - correct answerRestrains production of bacteria. The patient
needs a good immune system.
Minimum inhibitory concentration (MIC) - correct answerMin. amount of abx used to
inhibit growth of bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... - correct answerTake ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)
General side effects of abx - correct answerHypersensitivity: (allergic reaction-rash,
itching, LBP, wheezing, SOA).
Diarrhea: make sure to report blood, mucous
Superinfection: Due to disruption of normal flora (oral thrush, yeast infection)
True or False: Is extended care more likely to cause diarrhea? - correct answerTrue
Examples of Beta-Lactam Abx? - correct answerPCN & Cephalosporins
What do Beta-Lactam abx have on them? - correct answerA ring- that works by
disrupting the biosynthesis of the cell wall.
Intact ring is essential for antibacterial activity? True or False - correct answerTrue
True or false- A beta-lactamase inhibitor can be combine with an abx to form a beta-
lactamase resistant compound? - correct answerTrue
Updated Study Guide & Practice Questions |
100% Pass Guarantee
Narrow Specturm - correct answerTreat limited # of organisms, Less likely to disrupt
normal flora, organism identified.
Broad Specturm - correct answerTreats multiple organisms, more likely to disrupt
normal flora, causative agent unknown.
Why would you select abx? - correct answerIs antimicrobial therapy indicated, make a
clinical diagnosis, collection of specimens for a cx or lab test, make microbial diagnosis,
select drug.
Extended spectrum - correct answertreats multiple organisms, more likely to disrupt
normal flora, used when causative organism is unknown.
Gram positive - correct answerPurple, thick layer
Example of gram positive - correct answerGroup A beta-strep
Strep PNA
Gram negative - correct answerRed or pink, thin layer
Example of gram negative - correct answerH. influenza
N. Gonoccocus
Atypical Organism - correct answercolorless, no layer
Example of Atypical organism - correct answerMacrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-lactum abx - correct answerTrue
Risk factors for Drug Resistant Strep PNA (DRSP) - correct answerRecent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10 mg/day long term).
, Treatment for Drug Resistant Strep PNA - correct answerHigh dose amoxicillin 3-4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... - correct answerAllergy history (PCN- risk
of cross allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? - correct answertetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or baceriostiatic? - correct
answerBactericidals
What are bactericidals? - correct answerKills bacteria
What are bacteriostatic? - correct answerRestrains production of bacteria. The patient
needs a good immune system.
Minimum inhibitory concentration (MIC) - correct answerMin. amount of abx used to
inhibit growth of bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... - correct answerTake ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)
General side effects of abx - correct answerHypersensitivity: (allergic reaction-rash,
itching, LBP, wheezing, SOA).
Diarrhea: make sure to report blood, mucous
Superinfection: Due to disruption of normal flora (oral thrush, yeast infection)
True or False: Is extended care more likely to cause diarrhea? - correct answerTrue
Examples of Beta-Lactam Abx? - correct answerPCN & Cephalosporins
What do Beta-Lactam abx have on them? - correct answerA ring- that works by
disrupting the biosynthesis of the cell wall.
Intact ring is essential for antibacterial activity? True or False - correct answerTrue
True or false- A beta-lactamase inhibitor can be combine with an abx to form a beta-
lactamase resistant compound? - correct answerTrue
