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PNCB Acute Care CPNP-AC Practice Test: 150 Questions with Answers & Rationales

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Prepare for the CPNP-AC exam with our comprehensive practice test. This resource features 150 high-yield questions, complete with detailed correct answers and expert rationales. Test your knowledge of pediatric acute care nursing and identify areas for review before your certification test.

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Latest PNCB Acute Care Certification Practice Test
With 150 questions and Correct Answers with
Rationales/ PNCB Acute Care Practice Exam (New)


A client is admitted as sickle cell crisis with symptoms of
dyspnea and leg pain. The client's significant other says, "I
don't really understand why he is hurting so badly." Which
response by the nurse is best? - ...ANSWER...✓✓ -
Clumping of abnormal RBCs blocks blood flow through
the capillaries.


The nurse is teaching a client with sickle cell anemia how
to prevent crisis. Which foods should the nurse teach the
client to avoid - ...ANSWER...✓✓ - Alcoholic beverages


The nurse is determining the effectiveness of treatment
prescribed for a client with anemia. Which question
should the nurse use to make this evaluation? -
...ANSWER...✓✓ Are you keeping up with your work
schedule?"


The nurse is assessing a client diagnosed with chronic
leukemia. Which should the nurse focus on? (select all
that apply) - ...ANSWER...✓✓ - Fatigue

,2|Page



- Infection
- Social isolation


A client diagnosed with sickle cell anemia is experiencing
vaso-occlussive crisis. Which intervention would be
appropriate for this client? (select all that apply) -
...ANSWER...✓✓ - Administering oxygen
- Managing pain
- Encouraging rest


A client hospitalized with sickle cell frequently asks for
opioid pain medications often shortly after receiving a
dose. The nurse on the unit believes the client is drug
seeking. When the client requests pain medication, what
action by the nurse is best? - ...ANSWER...✓✓ Give the
client pain medication if it is time for another dose


A client is having diagnostic tests to determine the cause
of anemia. The nurse realizes that the test will focus on:
(select all that apply) - ...ANSWER...✓✓ - Disorders that
cause RBC destruction
- Disorders that reduce production of RBCs
- Presence of bleeding

,3|Page




The nurse at the hematology clinic is working with clients
who have polycythemia vera. Which client should the
nurse see first? - ...ANSWER...✓✓ - Client who reports
SOB


A nursing student is caring for a client with leukemia. The
nurse asked why the client is still at risk for infection
when client's WBC is high. What response by the nurse is
best? - ...ANSWER...✓✓ - While there is an increase in
WBCs, they are abnormal cells and won't provide
protection


A client has been admitted after sustaining a humerus
fracture that occurs when picking up the family cat. What
test result would the nurse correlate to this condition -
...ANSWER...✓✓ - Bence Jones protein in the urine


A client with thrombocytopenic purpura has had a
splenectomy and returned to the surgical unit from the
med-surg floor a few minutes ago. The nurse assesses
the client and finds the abdominal dressing saturated
with blood. What is the priority action of the nurse? -
...ANSWER...✓✓ - Take a set of vital signs and notify the
surgeon

, 4|Page




A client has thrombocytopenia. Which client statement
indicates that the client understands self-management of
this condition? - ...ANSWER...✓✓ - "I usually put ice on
bumps and bruises."


A nurse is caring for 4 clients with leukemia. After hand-
off report, which client should the nurse see first -
...ANSWER...✓✓ - The client who has 2 bloody diarrhea
stools this morning


A client's health record states that they have regular
infusions of factor 9. The nurse would justify and suspect
that this client has what diagnosis? - ...ANSWER...✓✓
Hemophilia


A nurse working with clients with sickle cell teaches
about self-management to prevent exacerbation of sickle
cell crisis. What factors should clients be taught to avoid?
- ...ANSWER...✓✓


A client who had a splenectomy 2 days ago complains of
malaise. The nurse checks the client's temperature and

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November 11, 2025
Number of pages
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Written in
2025/2026
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