1. What is blood?: - a connective tissue composed of a liquid portion called plasma and a cellular portion
consisting of various cells and cell fragments
2. What are the components of blood?: 55% plasma
45% RBCs
Small percentage of WBCs and platelets in buffy coat
3. What does plasma consist of?: - plasma proteins, including:
- albumins
- globulins (immunoglobulins/antibodies)
- fibrinogen
- waste moelcules
- nutrient molecules
- enzymes
- hormones
- gas
- electrolytes
4. What are the formed elements of blood?: - Erythrocytes (RBCs)
,- Leukocytes (WBCs)
- Platelets (thrombocytes)
5. What are the granular leukocytes?: Have granules in cytoplasm
- neutrophils
- basophils
- eosinophils
6. What are the agranular leukocytes?: - Lymphocytes (T cells and B cells)
- Monocytes
7. Does serum have proteins?: NO
8. What are the main components of RBCs and their function?: HEMOGLOBIN
- RBCs transport hemoglobin, which carry oxygen
ENZYMES
- contain carbonic anhydrase, which converts CO2 to bicarbonate
- serves as an acid-base buffer
, 9. What is the shape and relevance of RBCs?: Biconcave discs
- help RBCs pass through capillaries
10. What are the key RBC indices?: Hemoglobin concentration
- up to 34 g/dL in cells and about 15 g/dL in blood
- NO FREE hemoglobin plasma (only during hemolysis)
RBC count
- number of RBCs in a mcL
Hematocrit
- % of blood made up of RBCs
Mean Corpuscular Volume (MCV)
- average size of RBCs
Mean Corpuscular Hemoglobin (MCH)
- average concentration (weight) of hemoglobin in each RBC
Mean Corpuscular Hemoglobin Concentration (MCHC)
- average concentration (weight) of hemoglobin in a certain amount of blood