NR566-FINAL EXAM EXAM QUESTIONS WITH CORRECT VERIFIED ANSWERS 100% PASS (A+ CERTIFIED)
NR566-FINAL EXAM EXAM QUESTIONS WITH CORRECT VERIFIED ANSWERS 100% PASS (A+ CERTIFIED) 1. Why do men have higher hematocrit levels than women They produce more testosterone which results in higher amounts of erythropoietin and erythrocytes. 2. What is the Black Box warning for the androgen Oxandrolone? anabolic steroid: Can cause peliosis hepatitis; blood-filled cysts form in the liver leading to failure or intrabdominal hemorrhage 3. What are the disorders that the androgen testosterone can treat Hypogonadism (male), replacement therapy 4. What are the disorders that the androgen methyltestosterone can treat? Male Hormone: Replacement and hypogonadism in males 5. What are the disorders that the androgen oxandrolone can treat? anabolic steroid: Catabolic states (cachexia) 6. Testosterone can be used to treat what symptoms in post menopausal women Reduced genital sensitivity, fatigue, and decreased libido 7. What hormones does androgens suppress Luteinizing and follicle-stimulating 8. Which particle in the life cycle of chlamydia trachomatis is considered infectious and first infects the host cell elementary body 9. What is the recommended testing for males suspected to have Chlamydia first-catch urine for nucleic acid amplification test (NAAT) 10. What are the CDC screening recommendations for chlamydia in asymptomatic females annual screening annually in sexually active females 24 years or younger. 11. What is the recommend treatment for uncomplicated chlamydia in non-pregnant females and males doxycycline 100mg by mouth twice daily x7 days (alternate azithromycin 1g by mouth x1) 12. What is the mechanism of action of donepezil (Aricept)? Alzheimer's disease- : inhibits centrally active acetylcholinesterase 13. What are the common side effects of Aricept? Alzheimer's disease: gastrointestinal symptoms (nausea and diarrhea), headache, dizziness, muscle weakness 14. List the precautions for Aricept? Alzheimer's disease: sick sinus syndrome and seizure disorder 15. When combined with _________ and __________ peripheral side effects and rate of elimination can be increased for Aricept? Alzheimer's disease: CYP2D6 & CYP3A4 16. What is the mechanism of action of Rivastigmine (Exelon)? mild to moderate dementia (memory loss and mental changes) associated with Alzheimer's disease or Parkinson's disease: acts centrally for both acetylcholinesterase and butyrylcholinesterase, thereby potentially increasing its efficacy 17. What are some common side effects of Exelon? mild to moderate dementia (memory loss and mental changes) associated with Alzheimer's disease or Parkinson's disease: GI symptoms, weakness, dizziness, tremor 18. What are some precautions to keep in mind with prescribing Exelon? mild to moderate dementia (memory loss and mental changes) associated with Alzheimer's disease or Parkinson's disease: Asthm/COPD, sick sinus syndrome, GI bleed, weight less than 50 kg 19. The Exelon transdermal patch is used for dementia associated with ____________.: Parkinson's disease 20. What are the 2 major metabolizing enzymes that increase galantamine (Razadyne) concentrations? Dementia: CYP3A4 and CYP2D6 21. What is the mechanism of action of galantamine (Razadyne)? Dementia: ele- vating acetylcholine (Ach) in the cerebral cortex, modulating the nicotinic Ach receptors to increase Ach release from existing presynaptic nerve terminals. Increases glutamate and serotonin levels 22. What are the common side effects of galantamine (Razadyne)? Dementia: GI symptoms, headache, dizziness, fatigue 23. What are the prescription precautions for galantamine (Razadyne)? Demen- tia: NSAID use, GI bleed, asthma or COPD, concurrent use with meds that decrease heart rate 24. What are contraindications for use of Galantamine (Razadyne)? Dementia: severe liver or renal impairment 25. What is the only N-methyl-D-aspartate (NMDA) approved to treat moderate to severe Alzheimer's disease? Dementia: Memantine (Namenda) 26. What is the mechanism of action of memantine (Namenda) Dementia: prevents overactivation of glutamine receptors 27. What are the common side effects of memantine (Namenda)? Dementia: gas- trointestinal symptoms (constipation, diarrhea, and weight gain) , urinary frequency, confusion, dizziness, headache, cough 28. What are the prescribing precautions for nemantine (Namenda)? Demen- tia: concurrent use with amantadine, rimantadine, ketamine, or dextromethorphan and severe renal or hepatic impairment 29. An increased risk for ____________ can occur when memantine (Namenda) is given with a cholinesterase Inhibitor? Dementia: Falls; do not drive due to delayed reactions 30. Drugs that treat Alzheimer's disease work on all patients and cure AD False 31. Which AD drug requires tapering when discontinuing the drug donepezil 32. What gender is most at risk for Alzheimer's female 33. What is the recommended start dose for rivastigmine to treat AD 1.5mg by mouth twice daily 34. Why are acetylcholinesterase inhibitors a problem for those with COPD the can increase acetylcholine at the synapses in the lungs leading to bronchoconstriction 35. What is the most effective drug for Parkinson's disease levodopa 36. Which 2 antipsychotics have demonstrated a reduction in neuropsychiatric symptoms with their use risperidone, olanzapine (schizophrenia) 37. Selegiline is contraindicated with which drugs? Parkinson disease and a major depressive disorder in adults: SSRI's; can cause fatal serotonin syndrome 38. What percentage of people globally are impacted by mental health disorders, neurological, and substance use disorders 30% 39. What percentage of children and adolescents are impacted by mental health disorders worldwide 20% 40. What 3 major drug classes treat bipolar disease mood stabilizers, antipsychotics, antidepressants
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