NR509 FINAL EXAM EXAM QUESTIONS WITH CORRECT VERIFIED ANSWERS AND RATIONALE | 100% PASS

NR509 FINAL EXAM EXAM QUESTIONS WITH CORRECT VERIFIED ANSWERS AND RATIONALE | 100% PASS 1. A 44-year-old female mathematician presents to clinic with a complaint of a mass in the right breast. Her partner noticed this mass 2 days ago, and the patient feels guilty because she has only had one mammogram and does not engage in breast self examination (BSE) on any regular basis. She has no family history of breast cancer, and her prior mammogram was ordered as a routine screening test at age 43 years after a brief discussion with her primary care provider. After a thorough investigation reveals a benign cyst, what advice should be given to this patient about screening for breast cancer in her age group? a. BSE is well evidenced, and all recommending agencies agree that it should be taught and reinforced. b. Clinical breast examination (CBE) is superior to BSE and should be a routine part of annual examinations starting at age 30 years. c. This patient was in compliance with the U.S. Preventive Services Task Fo: C. This patient was in compliance with the U.S. Preventive Services Task Force (USPSTF) recommendations for her age group and risk factors prior to her current complaint. The USPSTF recommends that women age 50 years discuss risks and benefits with their provider and decide on appropriate screening for their individual preferences and needs 2. A 42-year-old female website developer presents for an annual preventive examination with questions about breast cancer screening. She is concerned about the radiation exposure associated with mammography and is interested in magnetic resonance imaging (MRI) as a possible alternative for routine screening. She is otherwise healthy with no family history of breast, ovarian, or colon cancer. Which of the following is true about MRI as a screening modality for breast cancer in the general population? a. Breast cancer screening by MRI has been well studied in the general popu-lation. b. Sensitivity of screening for breast cancer increases with breast MRI at the expense of specificity. c. This patient is an ideal candidate for screening via breast MRI based on current evidence. d. Women at low lifetime risk of breast cancer (20%) are recommended to undergo screening MRI. e. Known BRCA1 or BRCA2 mutation is insufficient cr: b. Sensitivity of screening for breast cancer increases with breast MRI at the expense of specificity. Rationale: Sensitivity of screening for breast cancer increases with breast MRI at the expense of specificity. Increased sensitivity (in this case, higher-resolution imaging to pick up subtler disease) is often traded for reduced specificity (in the form of discovering many small items of no pathological significance). 3. A 35-year-old G0P0 woman presents to clinic with a complaint of bilateral nipple discharge. This discharge started several weeks ago and has occurred at irregular intervals since that time. She does not complain of local tenderness, redness, fever, or any other systemic symptoms aside from slightly irregular periods over the last few months. On examination, she is able to express a small amount of discharge, which is sent to the laboratory and found to be consistent with breast milk but without any signs of blood or pus. Screening laboratories are also sent, which reveal a normal blood count, metabolic panel, thyroid-stimulating hormone, and human chorionic gonadotropin (HCG) level. Further laboratories are still pending. Which of the following is the most likely diagnosis? a. Mastitis b. Ductal carcinoma in situ c. Paget disease of the breast d. Occult pregnancy e. Prolactinoma: e. Prolactinoma Rationale: Prolactinomas are pituitary tumors that secrete prolactin, which causes the production of breast milk and can suppress menstruation. 4. A 22-year-old G0P0 undergraduate student presents to clinic after finding a breast mass on breast self-examination (BSE) at home. The mass is nontender without skin changes, erythema, or overlying swelling. She has heard that most breast cancers are found by patients themselves, and she is very concerned that she may have breast cancer. Which of the following is true about BSE and self-detection of breast cancer? a. Most masses that women find at home and bring to a provider's attention turn out to be malignant. b. This patient is more likely to find a fibroadenoma than a cancer on self-ex-amination. c. The most likely breast mass this patient is likely to find in herself is an abscess complicating underlying mastitis. d. Because of this patient's age, breast masses should not be pursued with imaging and diagnosis because the risk of cancer is so low. e. BSE is universally recommended because of very high sensitivity: b. This patient is more likely to find a fibroadenoma than a cancer on self-examination. Rationale: This patient is more likely to find a fibroadenoma than a cancer on self-examination. In this patient's age range (15-25 years), palpable masses are most likely to be benign fibroadenomas. 5. A 48-year-old female psychologist presents to clinic with concerns about her breast cancer risk after an age-matched cousin was recently diagnosed with this disease. This cousin is the third family member on her father's side in as many years to be diagnosed with breast cancer, including the patient's own father, who had surgery and subsequent treatment 3 years ago for breast cancer. The patient has little other knowledge of her family history, only that her grandparents independently arrived from Eastern Europe near the end of World War II and were among very few members of their family that survived the war. The patient has read about testing for the breast cancer genes (BRCA1 and BRCA2) and desires further information about whether this would be appropriate for her. Which of the following is true about this patient's indications for BRCA testing? a. Her familial lineage is irrelevant to her risk of BRCA genes and: d. This patient carries several risk factors that together justify BRCA testing. Rationale: This patient has both a first-degree male relative with breast cancer and several relatives in the same lineage with breast cancer. Both of these suggest risk for the BRCA genes, but the BRCAPRO calculator can further refine the numerical risk and help decide if screening might be helpful. 6. A 68-year-old former paleontologist presents to clinic with concerns about her breast cancer risk. Her mother developed the disease in her 50s and died from it in her 60s. A younger cousin developed the disease a few years ago before the age of 50 years, but this individual was not tested for the BRCA1 and BRCA2 genes. In addition, the patient suffered from lymphoma in her 20s and had radiation to the chest. She did take hormone replacement therapy for a few years before d