1|Page
ACOG Infertility ACOG 2024 Literature Quiz
Questions With Complete Solutions
True or False: Pretest and post- test counseling are
essential and must be a part of any screening program.
- ....ANSWER ....✔✔ True
What is aneuploidy? - ....ANSWER ....✔✔ Having one
or more extra chromosomes
How common are chromosomal abnormalities in live
births? - ....ANSWER ....✔✔ 1/150 live births are
affected with a chromosome abnormality
Name three factors that increase the chance for a
chromosome abnormality - ....ANSWER ....✔✔ 1.
Maternal Age
2. Previous pregnancy affected with a chromosome
abnormality
3. Ultrasound abnormalities
Do ACOG practice guidelines dictate an exclusive
course of treatment? - ....ANSWER ....✔✔ No
,2|Page
The information is designed to aid practitioners in
making decisions about appropriate obstetric and
gynecologic care. Variations in practice may be
warranted based on the needs of the individual patient,
resources, and limitations unique to the institution or type
of practice.
What is the most common autosomal trisomy? -
....ANSWER ....✔✔ Trisomy 21 (Down syndrome)
What is the most common sex chromosome abnormality?
- ....ANSWER ....✔✔ 47, XXY Klinefelter syndrome
How common is Klinefelter syndrome? - ....ANSWER
....✔✔ 1/500 males are affected or 1/1,000 births
What is the only viable monosomy? - ....ANSWER
....✔✔ Turner syndrome (45, X)
What percentage of cases of Down syndrome are
caused by non-disjunction? - ....ANSWER ....✔✔ 95%
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What is the median survival of individuals affected with
Down syndrome in economically developed countries? -
....ANSWER ....✔✔ Approximately 60 years of age
What percentage of pregnancies affected with Down
syndrome end in miscarriage or stillbirth? - ....ANSWER
....✔✔ 43%
Does ACOG discourage women who have a negative
screening test for aneuploidy from having a procedure
such as amnio or CVS so that diagnostic testing such as
microarray or chromosome analysis can be performed -
....ANSWER ....✔✔ No, even if a woman has had
negative aneuploidy screening ACOG supports the
option of diagnostic testing should that patient want it
Who does ACOG recommend should be offered the
option of diagnostic testing as well as aneuploidy
screening and when? - ....ANSWER ....✔✔ All women
regardless of their age should be offered screening and
diagnostic testing early in pregnancy
What percentage of pregnancies affected with Down
syndrome occur in women 35 or older at the time of
ACOG Infertility ACOG 2024 Literature Quiz
Questions With Complete Solutions
True or False: Pretest and post- test counseling are
essential and must be a part of any screening program.
- ....ANSWER ....✔✔ True
What is aneuploidy? - ....ANSWER ....✔✔ Having one
or more extra chromosomes
How common are chromosomal abnormalities in live
births? - ....ANSWER ....✔✔ 1/150 live births are
affected with a chromosome abnormality
Name three factors that increase the chance for a
chromosome abnormality - ....ANSWER ....✔✔ 1.
Maternal Age
2. Previous pregnancy affected with a chromosome
abnormality
3. Ultrasound abnormalities
Do ACOG practice guidelines dictate an exclusive
course of treatment? - ....ANSWER ....✔✔ No
,2|Page
The information is designed to aid practitioners in
making decisions about appropriate obstetric and
gynecologic care. Variations in practice may be
warranted based on the needs of the individual patient,
resources, and limitations unique to the institution or type
of practice.
What is the most common autosomal trisomy? -
....ANSWER ....✔✔ Trisomy 21 (Down syndrome)
What is the most common sex chromosome abnormality?
- ....ANSWER ....✔✔ 47, XXY Klinefelter syndrome
How common is Klinefelter syndrome? - ....ANSWER
....✔✔ 1/500 males are affected or 1/1,000 births
What is the only viable monosomy? - ....ANSWER
....✔✔ Turner syndrome (45, X)
What percentage of cases of Down syndrome are
caused by non-disjunction? - ....ANSWER ....✔✔ 95%
, 3|Page
What is the median survival of individuals affected with
Down syndrome in economically developed countries? -
....ANSWER ....✔✔ Approximately 60 years of age
What percentage of pregnancies affected with Down
syndrome end in miscarriage or stillbirth? - ....ANSWER
....✔✔ 43%
Does ACOG discourage women who have a negative
screening test for aneuploidy from having a procedure
such as amnio or CVS so that diagnostic testing such as
microarray or chromosome analysis can be performed -
....ANSWER ....✔✔ No, even if a woman has had
negative aneuploidy screening ACOG supports the
option of diagnostic testing should that patient want it
Who does ACOG recommend should be offered the
option of diagnostic testing as well as aneuploidy
screening and when? - ....ANSWER ....✔✔ All women
regardless of their age should be offered screening and
diagnostic testing early in pregnancy
What percentage of pregnancies affected with Down
syndrome occur in women 35 or older at the time of
