RNA 805 QUIZ 2 EXAM QUESTIONS AND ANSWERS
Select two rapid-acting anticonvulsants readily available when a perioperative seizure occurs. - CORRECT
ANSWER✅✅Propofol
Benzodiazepines
Which anticonvulsant agents induce CYP3A? (select two) - CORRECT ANSWER✅✅Phenytoin
Phenobarbital
Which anti-epileptic drug is least likely to produce aplastic anemia? - CORRECT ANSWER✅✅Gabapentin
A 70 kilogram patient is in status epilepticus. What would be an appropriate initial intravenous dose of
diazepam to treat the seizure? - CORRECT ANSWER✅✅7 mg
Antiepileptic drugs such as phenytoin, carbamazepine, and lamotrigine exert a significant part of their
anti-seizure effects by - CORRECT ANSWER✅✅blocking sodium channels
You are preparing to induce a patient who takes phenytoin for the treatment of seizures. You know that
this patient would likely require a higher dose of - CORRECT ANSWER✅✅vecuronium
Which antiepileptic drug is reserved only for patients with intractable seizures due to its life-threatening
side effects? - CORRECT ANSWER✅✅Felbamate
Most antiepileptic drugs are highly bound to - CORRECT ANSWER✅✅albumin
You are assessing a patient in the preoperative area prior to taking her for general anesthesia. She takes
valproic acid for seizures and atorvastatin for her cholesterol. Her blood glucose level is normal, but she
exhibits ketones in her urine. You know that - CORRECT ANSWER✅✅this is a normal side effect of
valproic acid
Match the psychiatric medication with its salient characteristic. - CORRECT ANSWER✅✅Monoamine
oxidase inhibitor - Requires tyramine-free diet
,Lithium - Can produce polyuria
Amitryptiline - Structurally similar to phenothiazines
You are preparing to induce general anesthesia in a patient who takes citalopram for depression. You
know that citalopram places the patient at increased risk for - CORRECT ANSWER✅✅torsades de
pointes
What ECG alterations would you most likely see in patients taking tricyclic antidepressants? (select two)
- CORRECT ANSWER✅✅flattening of the T wave
widening of the QRS
The most common cardiac side effects of tricyclic antidepressants are (select two) - CORRECT
ANSWER✅✅increased heart rate
orthostatic hypotension
Which condition would be most likely to occur as a result of lithium therapy? - CORRECT
ANSWER✅✅Hypothyroidism
Sertraline and fluoxetine are examples of - CORRECT ANSWER✅✅selective serotonin reuptake
inhibitors
Serotonin syndrome can occur from overdose of many medications used in the treatment of psychiatric
disorders. What are the symptoms of serotonin syndrome? (select four) - CORRECT ANSWER✅✅Clonus
Hyperreflexia
Agitation
Delirium
The most common serious side effect of MAO inhibitors is - CORRECT ANSWER✅✅orthostatic
hypotension
, A patient taking MAO inhibitors exhibits hypotension under general anesthesia. The recommended
pharmacologic strategy to address the hypotension would be to administer - CORRECT ANSWER✅✅1/3
the usual dose of phenylephrine
Side effects of prolonged lithium use or lithium toxicity include - CORRECT ANSWER✅✅polyuria
A patient you are preparing to take to surgery states he takes buproprion for smoking cessation.
Compared to other antidepressant class medications, you know that buproprion exhibits an increased
incidence of - CORRECT ANSWER✅✅seizures
Which of the following is a potential side effect of 5-HT3 receptor antagonists? - CORRECT
ANSWER✅✅Prolongation of the QT interval
Granisetron has been shown to be significantly more effective at managing postoperative nausea and
vomiting if combined with - CORRECT ANSWER✅✅dexamethasone
The most common side effects from the administration of ondansetron are (select two) - CORRECT
ANSWER✅✅headache
diarrhea
The 5HT-3 receptor works by - CORRECT ANSWER✅✅acting upon a ligand-gated ion channel
Serotonin 5HT-3 receptor antagonists are used to treat - CORRECT ANSWER✅✅nausea and vomiting
How does the body eliminate ondansetron? - CORRECT ANSWER✅✅It is metabolized in the liver
Patients with which of the following conditions would be most likely to suffer an allergic reaction to
protamine? (select two) - CORRECT ANSWER✅✅Allergy to fish products
History of protamine zinc insulin use
Select two rapid-acting anticonvulsants readily available when a perioperative seizure occurs. - CORRECT
ANSWER✅✅Propofol
Benzodiazepines
Which anticonvulsant agents induce CYP3A? (select two) - CORRECT ANSWER✅✅Phenytoin
Phenobarbital
Which anti-epileptic drug is least likely to produce aplastic anemia? - CORRECT ANSWER✅✅Gabapentin
A 70 kilogram patient is in status epilepticus. What would be an appropriate initial intravenous dose of
diazepam to treat the seizure? - CORRECT ANSWER✅✅7 mg
Antiepileptic drugs such as phenytoin, carbamazepine, and lamotrigine exert a significant part of their
anti-seizure effects by - CORRECT ANSWER✅✅blocking sodium channels
You are preparing to induce a patient who takes phenytoin for the treatment of seizures. You know that
this patient would likely require a higher dose of - CORRECT ANSWER✅✅vecuronium
Which antiepileptic drug is reserved only for patients with intractable seizures due to its life-threatening
side effects? - CORRECT ANSWER✅✅Felbamate
Most antiepileptic drugs are highly bound to - CORRECT ANSWER✅✅albumin
You are assessing a patient in the preoperative area prior to taking her for general anesthesia. She takes
valproic acid for seizures and atorvastatin for her cholesterol. Her blood glucose level is normal, but she
exhibits ketones in her urine. You know that - CORRECT ANSWER✅✅this is a normal side effect of
valproic acid
Match the psychiatric medication with its salient characteristic. - CORRECT ANSWER✅✅Monoamine
oxidase inhibitor - Requires tyramine-free diet
,Lithium - Can produce polyuria
Amitryptiline - Structurally similar to phenothiazines
You are preparing to induce general anesthesia in a patient who takes citalopram for depression. You
know that citalopram places the patient at increased risk for - CORRECT ANSWER✅✅torsades de
pointes
What ECG alterations would you most likely see in patients taking tricyclic antidepressants? (select two)
- CORRECT ANSWER✅✅flattening of the T wave
widening of the QRS
The most common cardiac side effects of tricyclic antidepressants are (select two) - CORRECT
ANSWER✅✅increased heart rate
orthostatic hypotension
Which condition would be most likely to occur as a result of lithium therapy? - CORRECT
ANSWER✅✅Hypothyroidism
Sertraline and fluoxetine are examples of - CORRECT ANSWER✅✅selective serotonin reuptake
inhibitors
Serotonin syndrome can occur from overdose of many medications used in the treatment of psychiatric
disorders. What are the symptoms of serotonin syndrome? (select four) - CORRECT ANSWER✅✅Clonus
Hyperreflexia
Agitation
Delirium
The most common serious side effect of MAO inhibitors is - CORRECT ANSWER✅✅orthostatic
hypotension
, A patient taking MAO inhibitors exhibits hypotension under general anesthesia. The recommended
pharmacologic strategy to address the hypotension would be to administer - CORRECT ANSWER✅✅1/3
the usual dose of phenylephrine
Side effects of prolonged lithium use or lithium toxicity include - CORRECT ANSWER✅✅polyuria
A patient you are preparing to take to surgery states he takes buproprion for smoking cessation.
Compared to other antidepressant class medications, you know that buproprion exhibits an increased
incidence of - CORRECT ANSWER✅✅seizures
Which of the following is a potential side effect of 5-HT3 receptor antagonists? - CORRECT
ANSWER✅✅Prolongation of the QT interval
Granisetron has been shown to be significantly more effective at managing postoperative nausea and
vomiting if combined with - CORRECT ANSWER✅✅dexamethasone
The most common side effects from the administration of ondansetron are (select two) - CORRECT
ANSWER✅✅headache
diarrhea
The 5HT-3 receptor works by - CORRECT ANSWER✅✅acting upon a ligand-gated ion channel
Serotonin 5HT-3 receptor antagonists are used to treat - CORRECT ANSWER✅✅nausea and vomiting
How does the body eliminate ondansetron? - CORRECT ANSWER✅✅It is metabolized in the liver
Patients with which of the following conditions would be most likely to suffer an allergic reaction to
protamine? (select two) - CORRECT ANSWER✅✅Allergy to fish products
History of protamine zinc insulin use
