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Endocrine System NCLEX Questions (Test Bank)

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Master the endocrine system for the NCLEX with this comprehensive test bank. This free PDF download contains practice questions and answers covering diabetes, thyroid disorders, adrenal imbalances, and pituitary function. Test your knowledge on pharmacology, nursing priorities, and patient education to boost your confidence and pass your exam.

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Page 1 of 192


Endocrine NCLEX Test Bank (Latest 2025) Complete

Solution 100% Correct

The nurse is caring for a group of older patients in a long-term

care setting. Which physical changes in the patients should the

nurse investigate as signs of possible endocrine dysfunction?

A. Absent reflexes, diarrhea, and hearing loss

B. Hypoglycemia, delirium, and incontinence

C. Fatigue, constipation, and mental impairment

D. Hypotension, heat intolerance, and bradycardia

.....ANSWER.....C.

Changes of aging often mimic clinical manifestations of endocrine

disorders. Clinical manifestations of endocrine dysfunction such as

fatigue, constipation, or mental impairment in the older adult are

often missed because they are attributed solely to aging.

,Page 2 of 192


The nurse interviews a 50-year-old man with a history of type 2

diabetes mellitus, chronic bronchitis, and osteoarthritis who has a

fasting blood glucose of 154 mg/dL. Which medications, if taken

by the patient, may raise blood glucose levels?

A. Glargine (Lantus)

B. Prednisone (Deltasone)

C. Metformin (Glucophage)

D. Acetaminophen (Tylenol)

.....ANSWER.....B.

Prednisone is a corticosteroid that may cause glucose intolerance

in susceptible patients by increasing gluconeogenesis and insulin

resistance. Insulin (e.g., glargine) and metformin (an oral

hypoglycemic agent) decrease blood glucose levels.

Acetaminophen has a glucose-lowering effect.

,Page 3 of 192


The nurse is caring for a 36-year-old woman with possible

hypoparathyroidism after a thyroidectomy. It is most

appropriate for the nurse to assess for which clinical

manifestations?

A. Polyuria, polydipsia, and weight loss

B. Cardiac dysrhythmias and hypertension

C. Muscle spasms and hyperactive deep tendon reflexes

D. Hyperpigmentation, skin ulcers, and peripheral edema

.....ANSWER.....C.

Common assessment abnormalities associated with

hypoparathyroidism include tetany (muscle spasms) and

increased deep tendon reflexes. Hyperpigmentation is

associated with Addison's disease. Skin ulcers occur in patient

with diabetes. Edema is associated with hypothyroidism. Polyuria

and polydipsia occur in patients with diabetes mellitus or

diabetes insipidus. Weight loss occurs in hyperthyroidism or

, Page 4 of 192


diabetic ketoacidosis. Hypertension and cardiac dysrhythmias

may be caused by hyperthyroidism, hyperparathyroidism, or

pheochromocytoma.

An 18-year-old male patient is undergoing a growth hormone

stimulation test. The nurse should monitor the patient for

A. hypothermia.

B. hypertension.

C. hyperreflexia.

D. hypoglycemia. .....ANSWER.....D.

Insulin or arginine (agent that stimulates insulin secretion) is

administered for a growth hormone stimulation test. The nurse

should monitor the patient closely for hypoglycemia.

Hypothermia and hypertension are not expected in response to

insulin or arginine. Hyperreflexia is an autonomic complication of

spinal cord injury.

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