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VanM s s 01: s s Introductio n tosP a t h o p h y s i o l o gy
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th
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Edition
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MULTIPLE CHOICE s s
Which of the following would be the most likely cause of
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an iatrogenic disease?
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An inherited disorder ss ss
A combination of specific etiological factors
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An unwanted effect of a prescribed drug
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Prolonged exposure to toxic chemicals in the environment ss ss ss ss ss ss ss
ANS: C s s
The manifestations of a disease are best defined as the
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subjective feelings of discomfort during a chronic illness. ss ss ss ss ss ss ss
signs and symptoms of a disease. ss ss ss ss ss
factors that precipitate an acute episode of a chronic illness.
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early indicators of the prodromal stage of infection.
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ANS: B s s
3. The best definition of the term prognosis is the
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a. precipitating factors causing an acute episode. ss ss ss ss ss
b. number of remissions to be expected during the course of a chronic illness.
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c. predicted outcome or likelihood of recovery from a specific disease.
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d. exacerbations occurring during chronicmillness. ss ss ss
ANS: C s s
4. Which of the following is considered a systemic sign of disease?
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a. Swelling of the knee ss ss ss
b. Fever
c. Pain in the neck ss ss ss
d. Red rash on the face ss ss ss ss
ANS: B s s
5. Etiology is defined as the study of the ss ss s s ss ss ss ss
a. causes of a disease. ss ss ss
b. course of a disease. ss ss ss
c. expected complications of a disease. ss ss ss ss
d. manifestations of a disease. ss ss ss
ANS: A s s
6. A ss type of cellular adaptation in which there is a decrease in cell size is referred to as
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a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D s s
7. A change in a tissue marked by cells that vary in size and shape and show increased
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ss mit otic figures would be called
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,Test s s Bank s s For s s Gould's s s Pathophysiology for the He a lt h P r o fe s s io ns 7 th E ssdSietlilss 2
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a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C s s
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called
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a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B s s
9. When a group of cells in the body dies, the change is called
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a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D s s
10. Rigorous weightlifting/body building regimens may result in the skeletal muscle
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cel ls undergoing
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a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A s s
11. The term cancer refers to
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a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. ss
ANS: D s s
12. To which of the following does the term apoptosis refer?
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a. Increased rate of mitosis by certain cells ss ss ss ss ss ss
b. Ischemic damage to cells ss ss ss
c. Liquefaction of necrotic tissue ss ss ss
d. Preprogrammed cell self-destruction ss ss
ANS: D s s
13. Which of the following statements is TRUE?
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a. Alteration of DNA does not change cell function. ss ss ss ss ss ss ss
b. Damaged cells may be able to repair themselves. ss ss ss ss ss ss ss
c. All types of cells die at the same rate.
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d. Mild ischemia causes immediate cell death.
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ANS: B s s
14. Caseation necrosis refers to an area where ss ss ss ss ss ss
a. cell proteins have been denatured.
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,Test s s Bank s s For s s Gould's s s Pathophysiology for the He a lt h P r o fe s s io ns 7 th E ssdSietlilss 3
Material
b. cells are liquefied by enzymes. ss ss ss ss
c. dead cells form a thick cheesy substance.
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d. bacterial invasion has occurred. ss ss ss
ANS: C s s
15. Routine application of sun block to skin would be an example of
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a. an iatrogenic cause of cancer.
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b. a preventive measure.
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c. a precipitating factor.
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d. a predisposing condition.
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ANS: B s s
16. A ss circumstance that causes a sudden acute episode of a chronic disease to occur is termed
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a. latent stage. ss
b. predisposing factor. ss
c. incidence.
d. precipitating factor. ss
ANS: D s s
17. The term homeostasis refers to
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a. the causative factors in a particular disease.
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b. maintenance of a stable internal environment. ss ss ss ss ss
c. a condition that triggers an acute episode.
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d. a collection of signs and symptoms.
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ANS: B s s
18. Which term is used to describe a new and secondary or additional problem that arises
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after the original disease has been established?
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a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS: D s s
19. Pathophysiology involves the study of ss ss ss ss
a. the structure of the human body.
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b. the functions of various organs in the body.
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c. functional or structural changes resulting from disease processes. ss ss ss ss ss ss ss
d. various cell structures and related functions. ss ss ss ss ss
ANS: C s s
20. Which of the following is the best definition of epidemiology?
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a. The science of tracking the occurrence and distribution of diseases
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b. The relative number of deaths resulting from a particular disease
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c. Identification of a specific disease through evaluation of signs and symptoms ss ss ss ss ss ss ss ss ss ss
d. The global search for emerging diseases
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ANS: A s s
, Test s s Bank s s For s s Gould's s s Pathophysiology for the He a lt h P r o fe s s io ns 7 th E ssdSietlilss 4
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21. Which of the following can cause cell injury or death?
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1.Hypoxia
2.Exposure to excessive cold ss ss ss
3.Excessive pressure on a tissue ss ss ss ss
4.Chemical toxins ss
a. 1, 2 ss
b. 2, 4 ss
c. 1, 3, 4 ss ss
d. 1, 2, 3, 4 ss ss ss
ANS: D s s
22. All of the following are part of the Seven Steps to Health EXCEPT:
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a. Follow cancer screening guidelines. ss ss ss
b. Use sun block agents whenever exposed.
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c. Participate in strenuous exercise on a regular daily basis. ss ss ss ss ss ss ss ss
d. Choose high fiber, lower fat foods. ss ss ss ss ss
ANS: C s s
23. The term disease refers to
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a. the period of recovery and return to a normal healthy state.
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b. a deviation from the normal state of health and function.
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c. the treatment measures used to promote recovery.
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d. a basic collection of signs and symptoms.
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ANS: B s s
24. A collection of signs and symptoms, often affecting more than one organ or
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system, t hat usually occur together in response to a certain condition is referred
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to as a(an)
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a. acute disease. ss
b. multiorgan disorder. ss
c. syndrome.
d. manifestation.
ANS: C s s
25. All of the following statements are correct about cell damage EXCEPT:
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a. The initial stage of cell damage often causes an alteration in metabolic reactions.
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b. If the factor causing the damage is removed quickly, the cell may be
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ss able to recover and return to its normal state.
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c. If the noxious factor remains for an extended period of time, the damage
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becom es irreversible and the cell dies.
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d. Initially, cell damage does not change cell metabolism, structure, or function.
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ANS: D s s
26. Which of the following conditions distinguishes double blind studies used in health research?
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a. Neither the members of the control group or the experimental group nor the
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pers on administering the treatment knows who is receiving the experimental
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therap y.ss ss
b. Both groups of research subjects and the person administering the treatment know
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w ho is receiving the experimental therapy.
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c. The research subjects do not know, but the person administering the
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treatme nt knows who is receiving placebo or standard therapy.
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