Pharmacotherapeutics for
Advanced Practice Providers
Burchum Rosenthal
Ch 59 Drug Therapy of Rheumatoid Arthritis 598. A patient will begin taking
hydroxychloroquine [Plaquenil] for rheumatoid arthritis. The patient is currently taking high-
dose NSAIDs and methotrexate. What will the nurse teach the patient? - ANSWERSa. That
an eye examination is necessary at the beginning of therapy with this drug
Ch 59 Drug Therapy of Rheumatoid Arthritis 599. A patient will begin taking etanercept
[Enbrel] for severe rheumatoid arthritis. The patient has been taking methotrexate
[Rheumatrex]. The patient asks if the etanercept is stronger than the methotrexate. The
nurse will tell the patient that etanercept methotrexate. - ANSWERSc. is better at delaying
progression of joint damage than
Ch 59 Drug Therapy of Rheumatoid Arthritis 600. A patient with rheumatoid arthritis is
taking leflunomide [Arava] and an oral contraceptive. She tells the nurse she would like to
get pregnant. What will the nurse tell her? - ANSWERSc. To ask her provider about an 11-
day course of cholestyramine
Ch 59 Drug Therapy of Rheumatoid Arthritis 601. A patient is beginning therapy with oral
methotrexate [Rheumatrex] for rheumatoid arthritis. The nurse will teach this patient about
the importance of: - ANSWERSa. having routine renal and hepatic function tests.
Ch 59 Drug Therapy of Rheumatoid Arthritis 602. A nurse is discussing the administration of
an intravenous infusion of rituximab (Rituxan) with a nursing student. Which statement by
the student indicates a need for further education about the care of a patient receiving this
drug? - ANSWERSa. "Angioedema and hypersensitivity may occur, but they are usually self-
limiting and mild."
Ch 59 Drug Therapy of Rheumatoid Arthritis 603. A patient who has been diagnosed with
rheumatoid arthritis (RA) for 1 month and has generalized symptoms is taking high-dose
nonsteroidal anti-inflammatory drugs (NSAIDs) and an oral glucocorticoid. The provider has
ordered methotrexate [Rheumatrex]. The patient asks the nurse why methotrexate is
,necessary since pain and swelling have been well controlled with the other medications. The
nurse will tell the patient that: - ANSWERSb. starting methotrexate early can help delay joint
degeneration.
Ch 60 Drug Therapy of Gout 604. A patient who has gout will begin taking febuxostat
[Uloric] and colchicine. What will the nurse include when teaching this patient about this
drug regimen? - ANSWERSe. That colchicine is used prophylactically to prevent acute gout
attacks when starting febuxostat
Ch 60 Drug Therapy of Gout 605. A patient with chronic gout is admitted to the hospital for
treatment for an infection. The patient is receiving allopurinol and ampicillin. The nurse is
preparing to administer medications and notes that the patient has a temperature of 101° F
and a rash. What will the nurse do? - ANSWERSa. Withhold the allopurinol and notify the
prescriber of the drug reaction.
Ch 60 Drug Therapy of Gout 606. A patient with chronic gout has an acute gouty episode
and is admitted to the hospital. The patient has been taking nonsteroidal anti-inflammatory
drugs for several months. The prescriber plans to begin therapy with probenecid. What will
the nurse do? - ANSWERSd. Suggest delaying the probenecid therapy until the acute
episode has subsided.
Ch 60 Drug Therapy of Gout 607. A patient is being treated with warfarin [Coumadin] to
prevent thrombus. The patient develops hyperuricemia, and the provider orders allopurinol
[Zyloprim]. The nurse will contact the provider to discuss the dose. - ANSWERSd. reducing;
warfarin
Ch 60 Drug Therapy of Gout 608. A patient who will begin taking colchicine for gout reports
taking nonsteroidal anti-inflammatory drugs, simvastatin, amoxicillin, and digoxin. What will
the nurse do? - ANSWERSb. Notify the provider about the potential risk of muscle injury
when simvastatin is taken with colchicine.
Ch 60 Drug Therapy of Gout 609. A patient who is hospitalized for an acute gout attack has
received several doses of hourly oral colchicine but still reports moderate to severe pain. As
the nurse prepares to administer the next dose, the patient begins vomiting. What will the
nurse do? - ANSWERSb. Hold the medication and notify the prescriber.
,Ch 60 Drug Therapy of Gout 610. A patient with gout who has increasingly frequent acute
gouty attacks will begin receiving allopurinol [Zyloprim] and colchicine. The nurse will
include which statement when teaching the patient about this drug regimen? - ANSWERSd.
"You will take both drugs initially and then stop taking the colchicine."
Ch 60 Drug Therapy of Gout 611. A patient has had three gouty flare-ups in the past year.
Which drug class will the nurse expect the provider to order for this patient? - ANSWERSd.
Urate-lowering drugs
Ch 60 Drug Therapy of Gout 612. A patient is admitted for treatment of gout that has been
refractory to treatment with allopurinol and probenecid. The patient is taking colchicine,
and the prescriber orders pegloticase [Krystexxa]. Before administering this drug, the nurse
will expect to: - ANSWERSa. administer an antihistamine and a glucocorticoid.
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 613. A nurse provides
teaching for a woman who will begin taking supplemental calcium. Which statement by the
woman indicates understanding of the teaching? - ANSWERSb. "I should not take more than
600 mg of calcium at one time."
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 614. A nurse is preparing to
administer IV calcium chloride to a patient with a low serum calcium level. Which drug on
the patient's medication record, administered concurrently, would require additional
patient monitoring by the nurse? - ANSWERSa. Digoxin [Lanoxin]
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 615. A nurse is providing
teaching for a patient with osteoporosis who has just switched from alendronate [Fosamax]
to zoledronate [Reclast]. Which statement by the patient indicates a need for further
teaching? - ANSWERSc. "This drug is less likely to cause osteonecrosis of the jaw."
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 616. A patient with severe
glucocorticoid-induced osteoporosis will start therapy with teriparatide [Forteo]. What will
the nurse expect to administer? - ANSWERSa. 20 μg once daily subQ
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 617. A nurse is discussing the
role of vitamin D in calcium regulation with a nursing student. Which statement by the
student indicates a need for further teaching? - ANSWERSa. "Adequate amounts of vitamin
D occur naturally in the diet."
, Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 618. A postmenopausal
patient develops osteoporosis. The patient asks the nurse about medications to treat this
condition. The nurse learns that the patient has a family history of breast cancer. The nurse
will suggest discussing which medication with the provider? - ANSWERSc. Raloxifene [Evista]
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 619. A patient has severe
Paget disease of the bone. The patient asks the nurse what can be done to alleviate the
pain. The nurse will suggest that the patient discuss the use of which medication with the
provider? - ANSWERSc. Calcitonin-salmon [Miacalcin]
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 620. A patient with metastatic
cancer has had several fractures secondary to bone metastases. The provider orders
denosumab [Xgeva]. What will the nurse teach this patient? - ANSWERSa. Denosumab may
delay healing of these fractures.
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 621. A patient taking
risedronate IR [Actonel] for osteoporosis reports experiencing diarrhea and headaches.
What will the nurse tell this patient? - ANSWERSa. These are common side effects of this
drug.
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 622. A 55-year-old female
patient asks a nurse about calcium supplements. The nurse learns that the patient
consumes two servings of dairy products each day. The patient's serum calcium level is 9.5
mg/dL. The serum vitamin D level is 18 ng/mL. The nurse will recommend adding: -
ANSWERSc. 600 mg of calcium once daily and 10,000 IU of vitamin D3 each day.
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 623. A patient who has
developed postmenopausal osteoporosis will begin taking alendronate [Fosamax]. The
nurse will teach this patient to take the drug: - ANSWERSc. while sitting upright with plenty
of water
Ch 61 Drugs Affecting Calcium Levels and Bone Mineralization 624. A patient is taking
alendronate [Fosamax] to treat Paget disease. The patient asks the nurse why calcium
supplements are necessary. The nurse will tell the patient that calcium supplements are
necessary to: - ANSWERSd. prevent hyperparathyroidism.