HESI NCLEX -PN Examination Review / HESI
NCLEX-PN Examination Review | 2025
Updated | Verified Questions & Detailed
Rationales
A 43-year-old female client who has had a thyroidectomy due to Grave's disease is
prescribed a thyroid replacement hormone. Which signs and symptoms are
associated with thyroid hormone toxicity and should be reported promptly to the
health care provider? - ---✔✔✔ANSWER----a. Tinnitus and dizziness
b. Tachycardia and chest pain
c. Dry skin and intolerance to cold
d. Weight gain and increased appetite
B
,The dosing of heparin intravenous infusion is guided by which laboratory value? -
---✔✔✔ANSWER----a. Prothrombin time
b. Fibrin split products
c. Platelet count
d. Partial thromboplastin time
D
A client receiving the antibiotic vancomycin is prescribed to have a peak and
trough level done with the next dose. What time should the practical nurse obtain
the blood specimen for the trough level? - ---✔✔✔ANSWER----a. 60
minutes after the antibiotic dose is administered.
b. Immediately before the next antibiotic dose is given.
c. When the next blood glucose level is to be checked.
d. 30 minutes before the next antibiotic dose is given.
B
The nurse is caring for a client who is taking prednisone to treat rheumatoid
arthritis. The nurse expects which aspect of care to be emphasized with this
client? - ---✔✔✔ANSWER----a. Reducing the dose of insulin
b. Monitoring for hyperkalemia
c. Monitoring for substance abuse
d. Treating infections as soon as they occur
D
,A client prescribed glipizide asked why they had to take their insulin orally. How
should the practical nurse respond? - ---✔✔✔ANSWER----a. "Glipizide is
an oral form of insulin and has the same actions and properties as intermediate
insulin."
b. "Glipizide is an oral form of insulin and is distributed, metabolized, and excreted
in the same manner as insulin."
c. "Glipizide is not an oral form of insulin and can be used only when some beta
cell function is present."
d. "Glipizide is not an oral form of insulin, but it is effective for those who are
resistant to injectable insulins."
C
The practical nurse administered carbidopa-levodopa to a client diagnosed with
Parkinson disease. Which outcome by the client would indicate a therapeutic
response?
a. Decreased blood pressure - ---✔✔✔ANSWER----a. Decreased blood
pressure
b. Lessening of tremors
c. Increased salivation
d. Increased attention span
B
The health care provider (HCP) has prescribed a 74-year-old client to be
vaccinated with the influenza vaccine prior to discharge. Which client condition
will make the practical nurse not to vaccinate the client and consult with the
charge nurse? - ---✔✔✔ANSWER----a. History of congested heart failure
, b. History of an allergy to eggs
c. History of pneumococcal vaccination
d. History of end-stage renal disease
B
A client who is taking hydrochlorothiazide is admitted to the hospital and is
experiencing muscle weakness and cramps. Which condition should the practical
nurse suspect is causing these changes? - ---✔✔✔ANSWER----a.
Hypolipidemia
b. Hypermagnesemia
c. Hyperchloremia
d. Hyponatremia
D
A client who was diagnosed with oral thrush calls the clinic saying the medication
bottle broke and all of the medication was spilled. The client is requesting a refill
order. The nurse should contact the health care provider about a refill for which
medication? - ---✔✔✔ANSWER----a. Ampicillin
b. Ciprofloxacin
c. Neomycin sulfate
d. Nystatin
D
A client with angina pectoris has been prescribed nitroglycerin tablets prn for
chest pain. Which statement by the client causes the practical nurse (PN) to clarify
NCLEX-PN Examination Review | 2025
Updated | Verified Questions & Detailed
Rationales
A 43-year-old female client who has had a thyroidectomy due to Grave's disease is
prescribed a thyroid replacement hormone. Which signs and symptoms are
associated with thyroid hormone toxicity and should be reported promptly to the
health care provider? - ---✔✔✔ANSWER----a. Tinnitus and dizziness
b. Tachycardia and chest pain
c. Dry skin and intolerance to cold
d. Weight gain and increased appetite
B
,The dosing of heparin intravenous infusion is guided by which laboratory value? -
---✔✔✔ANSWER----a. Prothrombin time
b. Fibrin split products
c. Platelet count
d. Partial thromboplastin time
D
A client receiving the antibiotic vancomycin is prescribed to have a peak and
trough level done with the next dose. What time should the practical nurse obtain
the blood specimen for the trough level? - ---✔✔✔ANSWER----a. 60
minutes after the antibiotic dose is administered.
b. Immediately before the next antibiotic dose is given.
c. When the next blood glucose level is to be checked.
d. 30 minutes before the next antibiotic dose is given.
B
The nurse is caring for a client who is taking prednisone to treat rheumatoid
arthritis. The nurse expects which aspect of care to be emphasized with this
client? - ---✔✔✔ANSWER----a. Reducing the dose of insulin
b. Monitoring for hyperkalemia
c. Monitoring for substance abuse
d. Treating infections as soon as they occur
D
,A client prescribed glipizide asked why they had to take their insulin orally. How
should the practical nurse respond? - ---✔✔✔ANSWER----a. "Glipizide is
an oral form of insulin and has the same actions and properties as intermediate
insulin."
b. "Glipizide is an oral form of insulin and is distributed, metabolized, and excreted
in the same manner as insulin."
c. "Glipizide is not an oral form of insulin and can be used only when some beta
cell function is present."
d. "Glipizide is not an oral form of insulin, but it is effective for those who are
resistant to injectable insulins."
C
The practical nurse administered carbidopa-levodopa to a client diagnosed with
Parkinson disease. Which outcome by the client would indicate a therapeutic
response?
a. Decreased blood pressure - ---✔✔✔ANSWER----a. Decreased blood
pressure
b. Lessening of tremors
c. Increased salivation
d. Increased attention span
B
The health care provider (HCP) has prescribed a 74-year-old client to be
vaccinated with the influenza vaccine prior to discharge. Which client condition
will make the practical nurse not to vaccinate the client and consult with the
charge nurse? - ---✔✔✔ANSWER----a. History of congested heart failure
, b. History of an allergy to eggs
c. History of pneumococcal vaccination
d. History of end-stage renal disease
B
A client who is taking hydrochlorothiazide is admitted to the hospital and is
experiencing muscle weakness and cramps. Which condition should the practical
nurse suspect is causing these changes? - ---✔✔✔ANSWER----a.
Hypolipidemia
b. Hypermagnesemia
c. Hyperchloremia
d. Hyponatremia
D
A client who was diagnosed with oral thrush calls the clinic saying the medication
bottle broke and all of the medication was spilled. The client is requesting a refill
order. The nurse should contact the health care provider about a refill for which
medication? - ---✔✔✔ANSWER----a. Ampicillin
b. Ciprofloxacin
c. Neomycin sulfate
d. Nystatin
D
A client with angina pectoris has been prescribed nitroglycerin tablets prn for
chest pain. Which statement by the client causes the practical nurse (PN) to clarify
